Mini-review: New therapeutic options in hypoparathyroidism

Endocrine

Volumn 41, Issue 3, 2012, Pages 410-414

  Cusano, Natalie E ^a   Rubin, Mishaela R ^a   Sliney Jr , James ^a   Bilezikian, John P ^a  

^a New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

Hypoparathyroidism; Parathyroid hormone; PTH(1 34); PTH(1 84); Teriparatide

Indexed keywords

CALCITRIOL; CALCIUM; PARATHYROID HORMONE; PARATHYROID HORMONE[1-34]; PLACEBO; VITAMIN D;

BONE EXAMINATION; BONE METABOLISM; BONE REMODELING; BONE TURNOVER; CALCIFICATION; CALCIUM BLOOD LEVEL; CONTINUOUS INFUSION; DENSITOMETRY; DOSAGE SCHEDULE COMPARISON; HUMAN; HYPERCALCIURIA; HYPOCALCEMIA; HYPOPARATHYROIDISM; MORPHOMETRICS; NAUSEA; PRIORITY JOURNAL; QUALITY OF LIFE; REVIEW; VITAMIN SUPPLEMENTATION;

EID: 84862662423     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-012-9618-y     Document Type: Review

References (20)

1. M.R. Rubin, J.P. Bilezikian, Hypoparathyroidism: clinical features, skeletal microstructure and parathyroid hormone replacement. Arq. Bras. Endocrinol. Metab. 54, 220-226 (2010)
2. S.H. Pearce, C. Williamson, O. Kifor et al., A familial syndrome of hypocalcemia with hypercalciuria due to mutations in the calciumsensing receptor. N. Engl. J. Med. 335, 1115-1122 (1996) (Pubitemid 26330965)
3. T. Sunthornthepvarakul, S. Churesigaew, S. Ngowngarmratana, A novel mutation of the signal peptide of the preproparathyroid hormone gene associated with autosomal recessive familial isolated hypoparathyroidism. J. Clin. Endocrinol. Metab. 84, 3792-3796 (1999) (Pubitemid 30645242)
4. M.R. Rubin, D.W. Dempster, H. Zhou et al., Dynamic and structural properties of the skeleton in hypoparathyroidism. J. Bone Miner. Res. 23, 2018-2024 (2008)
5. S. Abugassa, J. Nordenstrom, S. Eriksson, G. Sjoden, Bone mineral density in patients with chronic hypoparathyroidism. J. Clin. Endocrinol. Metab. 76, 1617-1621 (1993) (Pubitemid 23164388)
6. J.S. Touliatos, J.I. Sebes, A. Hinton et al., Hypoparathyroidism counteracts risk factors for osteoporosis. Am. J. Med. Sci. 310, 56-60 (1995)
7. M.R. Rubin, D.W. Dempster, T. Kohler et al., Three dimensional cancellous bone structure in hypoparathyroidism. Bone 46, 190-195 (2010)
8. M.R. Rubin, D.W. Dempster, J. Sliney Jr. et al., PTH(1-84) administration reverses abnormal bone-remodeling dynamics and structure in hypoparathyroidism. J. Bone Miner. Res. 26, 2727-2736 (2011)
9. T. Sikjaer, L. Rejnmark, L. Rolighed et al., The effect of adding PTH(1-84) to conventional treatment of hypoparathyroidism: a randomized, placebo-controlled study. J. Bone Miner. Res. 26, 2358-2370 (2011)
10. D. Shoback, Clinical practice. Hypoparathyroidism. N. Engl. J. Med. 359, 391-403 (2008)
11. J.P. Bilezikian, A. Khan, J.T. Potts Jr. et al., Hypoparathyroidism in the adult: epidemiology, diagnosis, pathophysiology, targetorgan involvement, treatment, and challenges for future research. J. Bone Miner. Res. 26, 2317-2337 (2011)
12. W. Arlt, C. Fremerey, F. Callies et al., Well-being, mood and calcium homeostasis in patients with hypoparathyroidism receiving standard treatment with calcium and vitamin D. Eur. J. Endocrinol. 146, 215-222 (2002) (Pubitemid 34162914)
13. G. Mazziotti, J. Bilezikian, E. Canalis et al., New understanding and treatments for osteoporosis. Endocrine 41, 58-69 (2012)
14. K.K. Winer, J.A. Yanovski, G.B. Cutler Jr., Synthetic human parathyroid hormone 1-34 vs calcitriol and calcium in the treatment of hypoparathyroidism. JAMA 276, 631-636 (1996) (Pubitemid 26278069)
15. K.K. Winer, J.A. Yanovski, B. Sarani, G.B. Cutler Jr., A randomized, cross-over trial of once-daily versus twice-daily parathyroid hormone 1-34 in treatment of hypoparathyroidism. J. Clin. Endocrinol. Metab. 83, 3480-3486 (1998) (Pubitemid 28500875)
16. K.K. Winer, C.W. Ko, J.C. Reynolds et al., Long-term treatment of hypoparathyroidism: a randomized controlled study comparing parathyroid hormone-(1-34) versus calcitriol and calcium. J. Clin. Endocrinol. Metab. 88, 4214-4220 (2003) (Pubitemid 37153722)
17. K.K. Winer, N. Sinaii, J. Reynolds et al., Long-term treatment of 12 children with chronic hypoparathyroidism: a randomized trial comparing synthetic human parathyroid hormone 1-34 versus calcitriol and calcium. J. Clin. Endocrinol. Metab. 95, 2680-2688 (2010)
18. K.K. Winer, B. Zhang, J.A. Shrader et al., Synthetic human parathyroid hormone 1-34 replacement therapy: a randomized crossover trial comparing pump versus injections in the treatment of chronic hypoparathyroidism. J. Clin. Endocrinol. Metab. (2011) [Epub ahead of print]
19. M.R. Rubin, J. Sliney Jr., D.J. McMahon et al., Therapy of hypoparathyroidism with intact parathyroid hormone. Osteoporos. Int. 21, 1927-1934 (2010)
20. N.E. Cusano, M.R. Rubin, D. McMahon D et al., Treatment of Hypoparathyroidism with PTH(1-84) is safe and effective for up to 4 years. J. Bone Miner. Res. 26(Suppl 1), S34 (2011). http://www.asbmr.org/Meetings/ AnnualMeeting/Abstract:2011.aspx. Accessed 11/04/11