Degradation in soil of precursors and by-products associated with the illicit manufacture of methylamphetamine: Implications for clandestine drug laboratory investigation

Forensic Science International

Volumn 220, Issue 1-3, 2012, Pages 245-250

  Pal, Raktim ^a   Megharaj, Mallavarapu ^a   Naidu, Ravi ^a   Klass, Gunter ^a   Cox, Matthew ^b   Kirkbride, K Paul ^c  

^a UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^b FORENSIC SCIENCE SA   (Australia)

^c Australian Federal Police   (Australia)

Author keywords

Clandestine lab; Dissolving metal reduction method; Illicit drug; Leuckardt method; Methylamphetamine; Nagai method; Nazi method

Indexed keywords

1 (1',4' CYCLOHEXADIENYL) 2 METHYLAMINOPROPANE; 1 BENZYL 3 METHYLNAPHTHALENE; CHEMICAL COMPOUND; ILLICIT DRUG; METHAMPHETAMINE; N FORMYLMETHYLAMPHETAMINE; PSEUDOEPHEDRINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CHEMICAL WASTE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG LEGISLATION; DRUG MANUFACTURE; FORENSIC SCIENCE; HALF LIFE TIME; LABORATORY TEST; LIMIT OF DETECTION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PRODUCT RECOVERY; RESIDUE ANALYSIS; SOIL ANALYSIS; SOIL DEGRADATION;

EID: 84862661743     PISSN: 03790738     EISSN: 18726283     Source Type: Journal    
DOI: 10.1016/j.forsciint.2012.03.011     Document Type: Article

References (13)

1. Janusz A., Kirkbride K.P., Scott R., Naidu R., Perkins M.V., Megharaj M. Microbial degradation of illicit drugs, their precursors, and manufacturing by-products: implications for clandestine drug laboratory investigation and environmental assessment. Forensic Sci. Int. 2003, 134:62-71.
2. Pal R., Megharaj M., Kirkbride K.P., Heinrich T., Naidu R. Biotic and abiotic degradation of illicit drugs, their precursor, and by-products in soil. Chemosphere 2011, 85:1002-1009.
3. Pal R., Megharaj M., Kirkbride K.P., Naidu R. Fate of 1-(1',4'-cyclohexadienyl)-2-methylaminopropane (CMP) in soil: route-specific by-product in the clandestine manufacture of methamphetamine. Sci. Total Environ. 2012, 416:394-399.
4. Crossley F.S., Moore M.L. Studies on the Leuckardt reaction. J. Org. Chem. 1944, 9:529-536.
5. Barron R.P., Kruegel A.V., Moore J.M., Kram T.C. Identification of impurities in illicit methamphetamine samples. J. Assoc. Off. Anal. Chem. 1974, 57:1147-1158.
6. Kirkbride K.P., Ward A.D., Jenkins N., Klass K., Coumbaros J. Synthesis of 4-methyl-5-arylpyrimidines and 4-arylpyrimidines: route specific markers for the Leuckardt preparation of amphetamine, 4-methoxyamphetamine, and 4-methylthioamphetamine. Forensic Sci. Int. 2001, 115:53-67.
7. Sinnema A., Verweij A.M.A. Impurities in illicit amphetamine: a review. Bull. Narcotics 1981, XXXIII:37-54.
8. Scott T.L., Janusz A., Perkins M.V., Megharaj M., Naidu R., Kirkbride K.P. Effect of amphetamine precursors and by-products on soil enzymes of two urban soils. Bull. Environ. Contam. Toxicol. 2003, 70:824-831.
9. Skinner H.F. Methamphetamine synthesis via hydroiodic acid/red phosphorous reduction of ephedrine. Forensic Sci. Int. 1990, 48:123-134.
10. Cantrell T.S., John B., Johnson L., Allen A.C. A study of impurities found in methamphetamine synthesized from ephedrine. Forensic Sci. Int. 1988, 39:39-53.
11. R. Pal, M. Megharaj, K.P. Kirkbride, R. Naidu, Adsorption and desorption characteristics of methamphetamine, 3,4-methylenedioxymethamphetamine, and pseudoephedrine in soils: implications for bioavailability, Sci. Total Environ., submitted for publication.
12. Ely R.A., McGrath D.C. Lithium-ammonia reduction of ephedrine to methamphetamine: an unusual clandestine synthesis. J. Forensic Sci. 1990, 35:720-723.
13. Person E.C., Meyer J.A., Vyvyan J.R. Structural determination of the principal byproduct of the lithium-ammonia reduction method of methamphetamine manufacture. J. Forensic Sci. 2005, 50:87-95.