AMG 386, a selective angiopoietin 1/2-neutralizing peptibody, inhibits angiogenesis in models of ocular neovascular diseases.

Investigative ophthalmology & visual science

Volumn 53, Issue 4, 2012, Pages 2170-2180

  Oliner, Jonathan D ^a   Bready, James ^b   Nguyen, Linh ^b   Estrada, Juan ^b   Hurh, Eunju ^b   Ma, Hongjin ^b   Pretorius, James ^b   Fanslow, William ^b   Nork, T Michael ^b   Leedle, Robert A ^b   Kaufman, Stephen ^b   Coxon, Angela ^b  

^a AMGEN INC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOPOIETIN 1; ANGIOPOIETIN 2; HYBRID PROTEIN; TREBANANIB;

ANIMAL; ARTICLE; AUTORADIOGRAPHY; C57BL MOUSE; CAPILLARY PERMEABILITY; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; EYE; FEMALE; FLUORESCENCE ANGIOGRAPHY; HUMAN; IN SITU HYBRIDIZATION; MACACA FASCICULARIS; MALE; METABOLISM; MOUSE; NEWBORN; PATHOLOGY; RETINA BLOOD VESSEL; RETINA NEOVASCULARIZATION; RETROLENTAL FIBROPLASIA; SUBRETINAL NEOVASCULARIZATION; TISSUE DISTRIBUTION;

ANGIOGENESIS INHIBITORS; ANGIOPOIETIN-1; ANGIOPOIETIN-2; ANIMALS; ANIMALS, NEWBORN; AUTORADIOGRAPHY; CAPILLARY PERMEABILITY; CHOROIDAL NEOVASCULARIZATION; DISEASE MODELS, ANIMAL; EYE; FEMALE; FLUORESCEIN ANGIOGRAPHY; HUMANS; IN SITU HYBRIDIZATION; INFANT, NEWBORN; MACACA FASCICULARIS; MALE; MICE; MICE, INBRED C57BL; RECOMBINANT FUSION PROTEINS; RETINAL NEOVASCULARIZATION; RETINAL VESSELS; RETINOPATHY OF PREMATURITY; TISSUE DISTRIBUTION;

EID: 84862634400     PISSN: None     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-7381     Document Type: Article

References (0)