The association of parental fatal and non-fatal suicidal behaviour with offspring suicidal behaviour and depression: A systematic review and meta-analysis

Psychological Medicine

Volumn 42, Issue 8, 2012, Pages 1567-1580

  Geulayov, G ^a   Gunnell, D ^a   Holmen, T L ^b   Metcalfe, C ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

Meta analysis; offspring depression; offspring suicidal behaviour; parental suicidal behaviour; systematic review

Indexed keywords

ADOLESCENT; AGE; CHILD; CONFIDENCE INTERVAL; DEPRESSION; FEMALE; HUMAN; MALE; META ANALYSIS; PARENT; PARENTAL DEPRIVATION; PSYCHOLOGICAL ASPECT; REVIEW; RISK; RISK FACTOR; SEX DIFFERENCE; STATISTICS; SUICIDE; SUICIDE ATTEMPT;

ADOLESCENT; AGE FACTORS; CHILD; CHILD OF IMPAIRED PARENTS; CONFIDENCE INTERVALS; DEPRESSIVE DISORDER; FEMALE; HUMANS; MALE; ODDS RATIO; PARENTAL DEATH; PARENTS; RISK FACTORS; SEX FACTORS; SUICIDE; SUICIDE, ATTEMPTED;

EID: 84862627104     PISSN: 00332917     EISSN: 14698978     Source Type: Journal    
DOI: 10.1017/S0033291711002753     Document Type: Article

References (55)

1. Agerbo E, Nordentoft M, Mortensen PB (2002). Familial, psychiatric, and socioeconomic risk factors for suicide in young people: nested case-control study. British Medical Journal 325, 74-77. (Pubitemid 34774879)
2. Brent D, Melhem N, Donohoe MB, Walker M (2009). The incidence and course of depression in bereaved youth 21 months after the loss of a parent to suicide, accident, or sudden natural death. American Journal of Psychiatry 166, 786-794.
3. Brent DA, Mann JJ (2005). Family genetic studies, suicide, and suicidal behavior. American Journal of Medical Genetics. Part C Seminars in Medical Genetics 133C, 13-24. (Pubitemid 40194125)
4. Brent DA, Oquendo M, Birmaher B, Greenhill L, Kolko D, Stanley B, Zelazny J, Brodsky B, Bridge J, Ellis S, Salazar JO, Mann JJ (2002). Familial pathways to earlyonset suicide attempt: risk for suicidal behavior in offspring of mood-disordered suicide attempters. Archives of General Psychiatry 59, 801-807. (Pubitemid 35001145)
5. Brent DA, Oquendo M, Birmaher B, Greenhill L, Kolko D, Stanley B, Zelazny J, Brodsky B, Firinciogullari S, Ellis SP, Mann JJ (2003). Peripubertal suicide attempts in offspring of suicide attempters with siblings concordant for suicidal behavior. American Journal of Psychiatry 160, 1486-1493. (Pubitemid 41070925)
6. Bronisch T, Lieb R (2008). Maternal suicidality and suicide risk in offspring. Psychiatric Clinics of North America 31, 213-221. (Pubitemid 351551420)
7. Brown AC, Sandler IN, Tein JY, Liu X, Haine RA (2007). Implications of parental suicide and violent death for promotion of resilience of parentally-bereaved children. Death Studies 31, 301-335.
8. Burke AK, Galfalvy H, Everett B, Currier D, Zelazny J, Oquendo MA, Melhem NM, Kolko D, Harkavy-Friedman JM, Birmaher B, Stanley B, Mann JJ, Brent DA (2010). Effect of exposure to suicidal behavior on suicide attempt in a high-risk sample of offspring of depressed parents. Journal of the American Academy of Child and Adolescent Psychiatry 49, 114-121.
9. Cain AC, Fast I (1966). Children's disturbed reactions to parent suicide. American Journal of Orthopsychiatry 36, 873-880.
10. Cerel J, Fristad MA, Weller EB, Weller RA (1999). Suicidebereaved children and adolescents: a controlled longitudinal examination. Journal of the American Academy of Child and Adolescent Psychiatry 38, 672-679. (Pubitemid 29250137)
11. Cerel J, Fristad MA, Weller EB, Weller RA (2000). Suicidebereaved children and adolescents: II. Parental and family functioning. Journal of the American Academy of Child and Adolescent Psychiatry 39, 437-444. (Pubitemid 30185538)
12. Christiansen E, Goldney RD, Beautrai AL, Agerbo E (2011). Youth suicide attempts and the dose-response relationship to parental risk factors: a population-based study. Psychological Medicine 41, 313-319.
13. Christoffersen MN, Poulsen HD, Nielsen A (2003). Attempted suicide among young people: risk factors in a prospective register based study of Danish children born in 1966. Acta Psychiatrica Scandinavica 108, 350-358. (Pubitemid 37305127)
14. Clark SE, Goldney RD (2000). The impact of suicide on relatives and friends. In The International Handbook of Suicide and Attempted Suicide (ed. K. Hawton and K. van Heeringen), pp. 467-484. John Wiley and Sons Ltd: Chichester.
15. Egeland JA, Sussex JN (1985). Suicide and family loading for affective disorders. JAMA 254, 915-918. (Pubitemid 15045209)
16. Fu Q, Heath AC, Bucholz KK, Nelson EC, Glowinski AL, Goldberg J, Lyons MJ, Tsuang MT, Jacob T, True MR, Eisen SA (2002). A twin study of genetic and environmental influences on suicidality in men. Psychological Medicine 32, 11-24. (Pubitemid 33150500)
17. Goodwin RD, Beautrais AL, Fergusson DM (2004). Familial transmission of suicidal ideation and suicide attempts: evidence from a general population sample. Psychiatry Research 126, 159-165. (Pubitemid 38581249)
18. Gravseth HM, Mehlum L, Bjerkedal T, Kristensen P (2010). Suicide in young Norwegians in a life course perspective: population-based cohort study. Journal of Epidemiology and Community Health 64, 407-412.
19. Grossman JA, Clark DC, Gross D, Halstead L, Pennington J (1995). Child bereavement after paternal suicide. Journal of Child and Adolescent Psychiatric Nursing 8, 5-17.
20. Hernan MA, Hernandez-Diaz S, Werler MM, Mitchell AA (2002). Causal knowledge as a prerequisite for confounding evaluation: an application to birth defects epidemiology. American Journal of Epidemiology 155, 176-184. (Pubitemid 34072741)
21. Higgins JPT, Green S (2008). Cochrane Handbook for Systematic Reviews of Interventions, version 5.0.2 (updated September 2009). The Cochrane Collaboration, 2009 (http://www.cochrane-handbook.org). Accessed 15 March 2011.
22. Hung NC, Rabin LA (2009). Comprehending childhood bereavement by parental suicide: a critical review of research on outcomes, grief processes, and interventions. Death Studies 33, 781-814.
23. Kessing LV, Agerbo E, Mortenssen PB (2004). Major stressful life events and other risk factors for first admission with mania. Bipolar Disorders 6, 122-129. (Pubitemid 38443565)
24. Kjoeller M, Helweg-Larsen M (2000). Suicidal ideation and suicide attempts among adult Danes. Scandinavian Journal of Public Health 28, 54-61.
25. Kuramoto SJ, Brent DA, Wilcox HC (2009). The impact of parental suicide on child and adolescent offspring. Suicide and Life-Threatening Behavior 39, 137-151.
26. Kuramoto SJ, Stuart EA, Runeson B, Lichtenstein P, Langstrom N, Wilcox HC (2010). Maternal or paternal suicide and offspring's psychiatric and suicide-attempt hospitalization risk. Pediatrics 126, e1026-e1032.
27. Lieb R, Bronisch T, Hofler M, Schreier A, Wittchen H-U (2005). Maternal suicidality and risk of suicidality in offspring: findings from a community study. American Journal of Psychiatry 162, 1665-1671. (Pubitemid 41318236)
28. McLeod JD (1991). Childhood parental loss and adult depression. Journal of Health and Social Behavior 32, 205-220.
29. Melhem NM, Brent DA, Ziegler M, Iyengar S, Kolko D, Oquendo M, Birmaher B, Burke A, Zelazny J, Stanley B, Mann JJ (2007). Familial pathways to early-onset suicidal behavior: familial and individual antecedents of suicidal behavior. American Journal of Psychiatry 164, 1364-1370. (Pubitemid 47461136)
30. Melhem NM, Walker M, Moritz G, Brent DA (2008). Antecedents and sequelae of sudden parental death in offspring and surviving caregivers. Archives of Pediatrics and Adolescent Medicine 162, 403-410. (Pubitemid 351656555)
31. Mitchell AM, Wesner S, Garand L, Gale DD, Havill A, Brownson L (2007). A support group intervention for children bereaved by parental suicide. Journal of Child and Adolescent Psychiatric Nursing 20, 3-13.
32. Mittendorfer-Rutz E, Rasmussen F, Wasserman D (2008). Familial clustering of suicidal behaviour and psychopathology in young suicide attempters. Social Psychiatry and Psychiatric Epidemiology 43, 28-36.
33. Niederkrotenthaler T, Floderus B, Alexanderson K, Rasmussen F, Mittendorfer-Rutz E (2010). Exposure to parental mortality and markers of morbidity, and the risks of attempted and completed suicide in offspring: an analysis of sensitive life periods. Journal of Epidemiology and Community Health. Published online: 5 October 2010. doi:10.1136/jech.2010.109595.
34. Nordentoft M, Sogaard M (2005). Registration, psychiatric evaluation and adherence to psychiatric treatment after suicide attempt. Nordic Journal of Psychiatry 59, 213-216. (Pubitemid 40946282)
35. Papadimitriou GN, Linkowski P, Delarbre C, Mendlewicz J (1991). Suicide on the paternal and maternal sides of depressed patients with a lifetime history of attempted suicide. Acta Psychiatrica Scandinavica 83, 417-419.
36. Pfeffer CR (1981). Parental suicide: an organising event in the development of latency age children. Suicide and Life-Threatening Behavior 11, 43-50. (Pubitemid 11084273)
37. Pfeffer CR (2000). Children bereaved after suicide: the need for a clinical and research agenda. In Lifesavers, vol. 12, no. 3 (ed. Anonymous), pp. 1, 6-7, 1. Canadian Mental Health Association: Ottawa.
38. Pfeffer CR, Karus D, Siegel K, Jiang H (2000). Child survivors of parental death from cancer or suicide: depressive and behavioral outcomes. Psycho-oncology 9, 1-10. (Pubitemid 30110385)
39. Pfeffer CR, Klerman GL, Hurt SW, Lesser M, Peskin JR, Siefker CA (1991). Suicidal children grow up: demographic and clinical risk factors for adolescent suicide attempts. Journal of the American Academy of Child and Adolescent Psychiatry 30, 609-616.
40. Pfeffer CR, Normandin L, Kakuma T (1994). Suicidal children grow up: suicidal behavior and psychiatric disorders among relatives. Journal of the American Academy of Child and Adolescent Psychiatry 33, 1087-1097. (Pubitemid 24296826)
41. Pfeffer CR, Normandin L, Kakuma T (1998). Suicidal children grow up: relations between family psychopathology and adolescents' lifetime suicidal behavior. Journal of Nervous and Mental Disease 186, 269-275. (Pubitemid 28232959)
42. Qin P, Agerbo E, Mortensen PB (2002). Suicide risk in relation to family history of completed suicide and psychiatric disorders: a nested case-control study based on longitudinal registers. Lancet 360, 1126-1130. (Pubitemid 35246486)
43. Roy A (1983). Family history of suicide. Archives of General Psychiatry 40, 971-974. (Pubitemid 13049072)
44. Roy A, Nielsen D, Rylander G, Sarchiapone M (2000). The genetics of suicidal behaviour. In The International Handbook of Suicide and Attempted Suicide (ed. K. Hawton and K. van Heeringen), pp. 209-221. John Wiley and Sons Ltd: Chichester.
45. Schulsinger F, Kety SS, Rosenthal D, Wender PH (1979). A family study of suicide. In Origin, Prevention and Treatment of Affective Disorders (ed. M. Schou and E. Tromgren), pp. 277-287. Academic Press: London.
46. Shepherd DM, Barraclough BM (1976). The aftermath of parental suicide for children. British Journal of Psychiatry 129, 267-276.
47. Sorensen HJ, Mortensen EL, Wang AG, Juel K, Silverton L, Mednick SA (2009). Suicide and mental illness in parents and risk of suicide in offspring. Social Psychiatry and Psychiatric Epidemiology 44, 748-751.
48. Sorenson SB, Rutter CM (1991). Transgenerational patterns of suicide attempt. Journal of Consulting and Clinical Psychology 59, 861-866.
49. Statham DJ, Heath AC, Madden PAF, Bucholz KK, Bierut L, Dinwiddie SH, Slutske WS, Dunne MP, Martin NG (1998). Suicidal behaviour: an epidemiological and genetic study. Psychological Medicine 28, 839-855. (Pubitemid 28393563)
50. Stenager K, Qin P (2008). Individual and parental psychiatric history and risk for suicide among adolescents and young adults in Denmark: a populationbased study. Social Psychiatry and Psychiatric Epidemiology 43, 920-926.
51. Suvisaari J, Hakkinen L, Haukka J, Lonnqvist J (2008). Mortality in offspring of mothers with psychotic disorder. Psychological Medicine 38, 1203-1210. (Pubitemid 351950147)
52. Tsuchiya KJ, Agerbo E, Mortensen PB (2005). Parental death and bipolar disorder: a robust association was found in early maternal suicide. Journal of Affective Disorders 86, 151-159. (Pubitemid 40780027)
53. Weller RA, Weller EB, Fristad MA, Bawa PK (2001). Suicidal behavior and parental psychopathology in hospitalized depressed children. Depression and Anxiety 14, 183-185. (Pubitemid 33097046)
54. Wender PH, Kety SS, Rosenthal D, Schulsinger F, Ortmann J, Lunde I (1986). Psychiatric disorders in the biological and adoptive families of adopted individuals with affective disorders. Archives of General Psychiatry 43, 923-929. (Pubitemid 17168411)
55. Wilcox HC, Kuramoto SJ, Lichtenstein P, Langstrom N, Brent DA, Runeson B (2010). Psychiatric morbidity, violent crime, and suicide among children and adolescents exposed to parental death. Journal of the American Academy of Child and Adolescent Psychiatry 49, 514-523.