Resting-state EEG study of comatose patients: A connectivity and frequency analysis to find differences between vegetative and minimally conscious states

Functional Neurology

Volumn 27, Issue 1, 2012, Pages 41-47

  Lehembre, Rémy ^a,c   Bruno, Marie Aurélie ^a   Vanhaudenhuyse, Audrey ^a   Chatelle, Camille ^a   Cologan, Victor ^a   Leclercq, Yves ^b   Soddu, Andrea ^b   Macq, Benoît ^c   Laureys, Steven ^a   Noirhomme, Quentin ^a  

^a University and University Hospital of Liège   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Connectivity; Disorders of consciousness; Imaginary part of coherency; Minimally conscious state; Phase lag index; Vegetative state

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COMA RECOVERY SCALE; COMATOSE PATIENT; ELECTROENCEPHALOGRAPHY; FEMALE; FREQUENCY ANALYSIS; HUMAN; MALE; MINIMALLY CONSCIOUS STATE; PERSISTENT VEGETATIVE STATE; POWER SPECTRUM; PROSPECTIVE STUDY; RATING SCALE; SENSE OF COHERENCE;

ADULT; AGED; ALPHA RHYTHM; CEREBRAL CORTEX; COMA; DELTA RHYTHM; DIAGNOSIS, DIFFERENTIAL; ELECTROENCEPHALOGRAPHY; FEMALE; HUMANS; MALE; MIDDLE AGED; MODELS, NEUROLOGICAL; PERSISTENT VEGETATIVE STATE; REST; THETA RHYTHM; YOUNG ADULT;

EID: 84862588464     PISSN: 03935264     EISSN: 19713274     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Laureys S, Celesia GG, Cohadon F et al. Unresponsive wakefulness syndrome: a new name for the vegetative state or apallic syndrome. BMC Med 2010;8:68
2. Jennett B, Plum F. Persistent vegetative state after brain damage. A syndrome in search of a name. Lancet 1972;1:734-737
3. Giacino JT, Ashwal S, Childs N, Cranford MR, Jennett B, Katz DI, et al. The minimally conscious state: definition and diagnostic criteria. Neurology 2002;58:349-353
4. Giacino J, Kalmar K. The vegetative and minimally conscious states: a comparison of clinical features and functional outcome. J Head Trauma Rehabil 1997;12:36-54
5. Majerus S, Gill-Thwaites H, Andrews K, Laureys S. Behavioral evaluation of consciousness in severe brain damage. Prog Brain Res 2005;150:397-413
6. Teasdale G, Jennett B. Assessment of coma and impaired consciousness. A practical scale. Lancet 1974;2:81-84
7. Giacino JT, Kalmar K, Whyte J. The JFK Coma Recovery Scale-Revised: measurement characteristics and diagnostic utility. Arch Phys Med Rehabil 2004;85:2020-2029
8. Schnakers C, Vanhaudenhuyse A, Giacino J, Ventura M, Boly M, Majerus S, et al. Diagnostic accuracy of the vegetative and minimally conscious state: clinical consensus versus standardized neurobehavioral assessment. BMC Neurol 2009;9:35
9. Luauté J, Maucort-Boulch D, Tell L et al. Long-term outcomes of chronic minimally conscious and vegetative states. Neurology 2010;75:246-252
10. Schiff ND, Rodriguez-Moreno D, Kamal A et al. fMRI reveals large-scale network activation in minimally conscious patients. Neurology 2005; 64:514-523
11. Boly M, Faymonville ME, Peigneux P et al. Auditory processing in severely brain injured patients-differences between the minimally conscious state and the persistent vegetative state. Arch Neurol 2004;61:233-238
12. Wijnen VJ, van Boxtel GJ, Eilander HJ, de Gelder B. Mismatch negativity predicts recovery from the vegetative state. Clin Neurophysiol 2007;118:597-605
13. Kotchoubey B, Lang S, Mezger G et al. Information processing in severe disorders of consciousness: vegetative state and minimally conscious state. Clin Neurophysiol 2005;116:2441-2453
14. Daltrozzo J, Wioland N, Mutschler V, Kotchoubey B. Predicting coma and other low responsive patients outcome using event-related brain potentials: a meta-analysis. Clin Neurophysiol 2007; 118:606-614
15. Coleman MR, Rodd JM, Davis MH et al. Do vegetative patients retain aspects of language comprehension? Evidence from fMRI. Brain 2007; 130:2494-2507
16. Monti MM, Vanhaudenhuyse A, Coleman MR et al. Willful modulation of brain activity in disorders of consciousness. N Engl J Med 2010;362:579-589
17. Owen AM, Coleman MR, Boly M, Davis MH, Laureys S, Pickard JD. Detecting awareness in the vegetative state. Science 2006;313:1402
18. Schnakers C, Perrin F, Schabus M et al. Voluntary brain processing in disorders of consciousness. Neurology 2008;71:1614-1620
19. Schnakers C, Ledoux D, Majerus S et al. Diagnostic and prognostic use of bispectral index in coma, vegetative state and related disorders. Brain Inj 2008;22:926-931
20. Nunez PL, Srinivasan R, Westdorp AF et al. EEG coherency I: statistics, reference electrode, volume conduction, Laplacians, cortical imaging, and interpretation at multiple scales. Electroencephalogr Clin Neurophysiol 1997;103:499-515
21. Srinivasan R, Nunez PL, Silberstein RB. Spatial filtering and neocortical dynamics: estimates of EEG coherence. IEEE Trans Biomed Eng 1998;45:814-826
22. Fein G, Raz J, Brown FF, Merrin EL. Common reference coherence data are confounded by power and phase effects. Electroencephalogr Clin Neurophysiol 1988;69:581-584
23. Florian G, Andrew C, Pfurtscheller G. Do changes in coherence always reflect changes in functional coupling? Electroencephalogr Clin Neurophysiol 1998;106:87-91
24. Lachaux JP, Rodriguez E, Martinerie J, Varela FJ. Measuring phase synchrony in brain signals. Hum Brain Mapp 1999;8:194-208
25. Mormann F, Lehnertz K, David P, Elger CE. Mean phase coherence as a measure for phase synchronization and its application to the EEG of epilepsy patients. Physica D 2000;144:358-369
26. Nolte G, Bai O, Wheaton L, Mari Z, Vorbach S, Hallett M. Identifying true brain interaction from EEG data using the imaginary part of coherency. Clin Neurophysiol 2004;115:2292-2307
27. Stam CJ, Nolte G, Daffertshofer A. Phase lag index: assessment of functional connectivity from multi channel EEG and MEG with diminished bias from common sources. Hum Brain Mapp 2007;28:1178-1193
28. Schnakers C, Majerus S, Giacino J, Vanhaudenhuyse A, Bruno MA, Boly M, et al. A French validation study of the Coma Recovery Scale-Revised (CRS-R). Brain Inj 2008;22:786-792
29. Leclercq Y, Maquet P, Noirhomme Q, Phillips C. fMRI Artefact rejection and Sleep Scoring Toolbox (FAST). http://www.montefiore.ulg.ac.be/phillips/toolbox.html: Cyclotron Research Centre, University of Liege, Belgium, 2009
30. Percival DB, Walden AT. Spectral Analysis for Physical Applications: Multitaper and Conventional Univariate Techniques. Cambridge; Cambridge University Press 1993
31. Leon-Carrion J, Martin-Rodriguez JF, Damas-Lopez J, Barrosoy Martin JM, Dominguez-Morales MR. Brain function in the minimally conscious state: A quantitative neurophysiological study. Clin Neurophysiol 2008;119:1506-1514
32. Brenner RP. The interpretation of the EEG in stupor and coma. Neurologist 2005;11:271-284
33. Thatcher R. EEG database-guided neurotherapy. In: Evans JR, Abarbanel A eds Introduction to Quantitative EEG and Neurofeedback. San Diego; Academic Press 1999: 29-60
34. Pollonini L, Pophale S, Situ N et al. Information communication networks in severe traumatic brain injury. Brain Topogr 2010;23:221-226.