Complete absence of the αGal xenoantigen and isoglobotrihexosylceramide in α1,3galactosyltransferase knock-out pigs

Xenotransplantation

Volumn 19, Issue 3, 2012, Pages 196-206

  Puga Yung, Gisella L ^a   Li, Yunsen ^b   Borsig, Lubor ^c   Millard, Anne Laure ^d   Karpova, Maria B ^e   Zhou, Dapeng ^b   Seebach, Jörg D ^a  

^a Children's Hospital of Geneva   (Switzerland)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^e UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

1,3galactosyltransferase; Isoglobotrihexosylceramide; Knockout pigs; Transplantation; Xenoantigen

Indexed keywords

ALPHA 1,3 GALACTOSYLTRANSFERASE; ANTIGEN; GALACTOSE; GALACTOSYLGALACTOSE; GLYCOSPHINGOLIPID; ISOGLOBOTRIHEXOSYLCERAMIDE; ISOGLOBOTRIHEXOSYLCERAMIDE SYNTHASE; LECTIN; MESSENGER RNA; SYNTHETASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN DETECTION; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ANTIGEN STRUCTURE; AORTA; ARTICLE; CELL SURFACE; CELLULAR IMMUNITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME ASSAY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HYPERACUTE GRAFT REJECTION; ION TRAP MASS SPECTROMETRY; KIDNEY; KNOCKOUT GENE; LIVER; LUNG; LYMPH NODE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN; SWINE; THYMUS; WILD TYPE; XENOTRANSPLANTATION;

ACUTE DISEASE; ANIMALS; ANTIGENS, HETEROPHILE; AORTA; DISACCHARIDES; ENDOTHELIAL CELLS; FEMALE; GALACTOSYLTRANSFERASES; GENE KNOCKDOWN TECHNIQUES; GLOBOSIDES; GRAFT REJECTION; PRIMATES; RNA, MESSENGER; SWINE; SWINE, MINIATURE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84862584602     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/j.1399-3089.2012.00705.x     Document Type: Article

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