Prenatal and neonatal exposure to perfluorooctane sulfonic acid results in changes in miRNA expression profiles and synapse associated proteins in developing rat brains

Environmental Science and Technology

Volumn 46, Issue 12, 2012, Pages 6822-6829

  Wang, Faqi ^a   Liu, Wei ^a   Ma, Junsheng ^a   Yu, Mingxi ^a   Jin, Yihe ^a   Dai, Jiayin ^b  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^b INSTITUTE OF ZOOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EXPRESSION PROFILE; MICROARRAY ANALYSIS; MICRORNAS; MRNA CHANGES; NEGATIVE REGULATORS; NEONATAL RAT; NEURODEVELOPMENT; PERFLUOROOCTANE SULFONIC ACIDS; PROTEIN LEVEL; RAT BRAIN; REGULATORY EFFECTS; UNDERLYING MECHANISM;

RATS;

PROTEINS;

BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; MESSENGER RNA; MICRORNA; MICRORNA 1; MICRORNA 10B; MICRORNA 126; MICRORNA 181C; MICRORNA 204; MICRORNA 207; MICRORNA 23A; MICRORNA 25; MICRORNA 297; MICRORNA 336; MICRORNA 346; MICRORNA 363; MICRORNA 466B; MICRORNA 466C; MICRORNA 665; MICRORNA 668; MICRORNA 672; MICRORNA 674 3P; MICRORNA 764; NERVE GROWTH FACTOR RECEPTOR; NEUROTROPHIN 3 RECEPTOR; PERFLUOROOCTANESULFONIC ACID; PROTEIN; SYNAPSE ASSOCIATED PROTEIN; SYT I PROTEIN; SYT XI PROTEIN; UNCLASSIFIED DRUG; VESICULAR GLUTAMATE TRANSPORTER 2;

ARRAY; BRAIN; CALCIUM; DEVELOPMENTAL BIOLOGY; GENE EXPRESSION; ORGANIC ACID; POLLUTION EXPOSURE; PROTEIN; RNA; RODENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN DEVELOPMENT; GESTATIONAL AGE; NONHUMAN; PRENATAL EXPOSURE; PROTEIN EXPRESSION; RAT; SYNAPSE; SYNAPTIC TRANSMISSION; UPREGULATION;

ALKANESULFONIC ACIDS; BRAIN; FEMALE; FLUOROCARBONS; GENE EXPRESSION PROFILING; HUMANS; MALE; MATERNAL EXPOSURE; MICRORNAS; NERVE TISSUE PROTEINS; PREGNANCY; SYNAPSES;

EID: 84862582491     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es3008547     Document Type: Article

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