Derivation of islet-like cells from mesenchymal stem cells using PDX1-transducing lentiviruses

Biotechnology and Applied Biochemistry

Volumn 59, Issue 3, 2012, Pages 205-212

  Talebi, Samira ^a   Aleyasin, Ahmad ^a   Soleimani, Masoud ^b   Massumi, Mohammad ^a  

^a NATIONAL INSTITUTE OF GENETIC ENGINEERING AND BIOTECHNOLOGY   (Iran)

^b TARBIAT MODARES UNIVERSITY   (Iran)

Author keywords

Insulin producing cells; Lentivirus; Mesenchymal stem cells; PDX1

Indexed keywords

BLOOD GLUCOSE LEVEL; CELL-BASED; DIABETIC RATS; GLUCOSE SENSING; IMMUNOFLUORESCENCE ANALYSIS; INSULIN SECRETION; LENTIVIRUS; MESENCHYMAL STEM CELL; PDX1; PROTEIN LEVEL; QUANTITATIVE REVERSE TRANSCRIPTION-POLYMERASE CHAIN REACTION; RAT BONE MARROW; REGULATORY GENES; TRANSDUCING; TYPE 1 DIABETES;

CELLS; FLOWCHARTING; GENES; GLUCOSE; INSULIN; RATS; TRANSCRIPTION;

CELL CULTURE;

GLUCAGON; GLUCOSE TRANSPORTER 2; NEUROGENIN 3; TRANSCRIPTION FACTOR PDX 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW; CELL BASED GENE THERAPY; CELL ISOLATION; GENE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; INSULIN RELEASE; LENTIVIRINAE; MALE; MESENCHYMAL STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET CELL; PANCREATIC DUODENUM HOMEOBOX PROTEIN 1 GENE; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CELL DIFFERENTIATION; DIABETES MELLITUS, EXPERIMENTAL; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC VECTORS; HOMEODOMAIN PROTEINS; ISLETS OF LANGERHANS; LENTIVIRUS; MALE; MESENCHYMAL STROMAL CELLS; POLYMERASE CHAIN REACTION; RATS; TRANS-ACTIVATORS;

EID: 84862576195     PISSN: 08854513     EISSN: 14708744     Source Type: Journal    
DOI: 10.1002/bab.1013     Document Type: Article

References (45)

1. Halban, P. A., Kahn, S. E., Lernmark, A., and Rhodes, C. J. (2001) Diabetes 50, 2181-2191.
2. Zhou, Q., Brown, J., Kanarek, A., Rajagopal, J., and Melton, D. A. (2008) Nature 455, 627-632.
3. Cao, H., Chul, Y., Zhu, H., Sun, J., Pu, Y., Gao, Z., Yang, C., Peng, S., Dou, Z., and Hua, J. (2011) Cell Prolif. 44, 19-32.
4. Seymour, P. A., Hsu, W., Dor, Y., Hsu W., Dor, Y., Sander, M., Magnuson, M. A., Serup, P., and Gu, G. (2009) Proc. Natl. Acad. Sci. U. S. A. 106, 9715-9720.
5. Zhu, F. F., Zhang, P. B., Zhang, D. H., Sui, X., Yin, M., Xiang, T. T., Shi, Y., Ding, M. X., and Deng, H. (2011) Diabetologia 54, 2325-2336.
6. Patricia, A. (2010) Mol. Biol. Cell 21, 1783-1787.
7. Soria, B., Roche, E., Berna, G., León-Quinto, T., Reig, J. A., and Martín, F. (2000) Diabetes 49, 157-162.
8. Kodama, S., Davis, M., and Faustman, D. (2010) Int. J. Biochem. Cell Biol. 42, 1576-1579.
9. Toma, J., Akhavan, M., Fernandes, K., Barnabé-Heider, F., Sadikot, A., Kaplan, D. R., and Miller, F. D. (2001) Nat. Cell Biol. 3, 778-784.
10. Okumura, K., Nakamura, K., Hisatomi, Y., Nagano, K., Tanaka, Y., Terada, K., Sugiyama, T., Umeyama, K., Matsumoto, K., Yamamoto, T., and Endo, F. (2003) Hepatology 38, 104-113.
11. Tropel, P., Noël, D., Platet, N., Legrand, P., Benabid, A. L., and Berger, F. (2004) Exp. Cell Res. 295, 395-406.
12. Hassan, T., and El-Sheemy, M. (2004) J. R. Soc. Med. 97, 465-471.
13. Wang, H., Hung, S., Peng, S., Huang, C. C., Wei, H. M., Guo, Y. J., Fu, Y. S., Lai, M. C., and Chen, C. C. (2004) Stem Cells 22, 1330-1337.
14. Kadner, A., Hoerstrup, S., Tracy, J., Breymann, C., Maurus, C. F., Melnitchouk, S., Kadner, G., Zund, G., and Turina, M. (2002) Ann. Thorac. Surg. 74, S1422-S1428.
15. Kadner, A., Zund, G., Maurus, C., Breymann C., Yakarisik, S., Kadner, G., Turina, M., and Hoerstrup, S. P. (2004) Eur. J. Cardiothorac. Surg. 25, 635-641.
16. Scharfmann, R. (2003) Eur. J. Clin. Invest. 33, 595-600.
17. Steve, K. (2006) Clin. Exp. Pharmacol. Physiol. 33, 489-495.
18. Lee, K., Kuo, T., Whang-Peng, J., Chung, Y. F., Lin, C. T., Chou, S. H., Chen, J. R., Chen, Y. P., and Lee, O. K. (2004) Hepatology 40, 1275-1284.
19. Woodlbury, D., Schwarz, E., Prockop, D., and Black, I. B. (2000) J. Neurosci. Res. 61, 364-370.
20. Edwin M. (2003) Arch. Med. Res. 34, 6, 600-606.
21. Qian, H., Zhang, X., Xu, W., Zhu, W., Cao, H., Chen, Y., Xu, X., Wang, M., Xie, Y., and Sun, J. (2010) Biotechnol. Appl. Biochem. 55, 53-62.
22. Scharfmann, R. (2000) Diabetologia 43, 1083-1092.
23. Hebrok, M. (2003) Mech. Dev. 120, 45-57.
24. Mashima, H., Ohnishi, H., Wakabayashi, K., Mine, T., Miyagawa, J., Hanafusa, T., Seno, M., Yamada, H., and Kojima, I. (1996) J. Clin. Invest. 97, 1647-1654.
25. Miller, C., McGehee, R., and Habener, J. (1994) EMBO J. 13, 1145-1156.
26. Watada, H., Kajimoto, Y., and Umayahara, Y. (1996) Diabetes 45, 1478-1488.
27. Li, Y., Zhang, R., Qiao, H., Zhang, H., Wang, Y., Yuan, H., Liu, Q., Liu, D., Chen, L., and Pei, X. (2007) J. Cell Physiol. 211, 36-44.
28. Pear, W. S., Nolan, G. P., Scott, M. L., and Baltimore, D. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 8392-8396.
29. Klages, N., Zufferey, R., and Trono, D. (2000) Mol. Ther. 2, 170-176.
30. Livak, K., and Schmittgen, T. (2001) Methods 25, 402-408.
31. Dhasarathan, P., and Theriappan, P. (2011) J. Med. Med. Sci. 2, 670-674.
32. Wang, H., Shyu, J., and Shen, W. (2011) Cell Transplant. 20, 455-466.
33. Kim, J., Shin, K., Li, T., and Suh, H. (2011) J. Tissue Eng. Regen. Med. 5, 761-769.
34. Douglas, J. (2007) Mol. Biotechnol. 36, 71-80.
35. Horwitz, E. M. (2003) Arch. Med. Res. 34, 600-606.
36. Pittenger, M. F., and Martin, B. J. (2004) Circ. Res. 95, 9-20.
37. Hare, J. M., Traverse, J. H., Henry, T. D., Dib, N., Strumpf, R. K., Schulman, S. P., Gerstenblith, G., DeMaria, A. N., Denktas, A. E., Gammon, R. S., Hermiller, J. B., Reisman, M. A., Schaer, G. L., and Sherman, W. (2009) J. Am. Coll. Cardiol. 54, 2277-2286.
38. Blanc, K. L., Samuelsson, H., Gustafsson B., Remberger, M., Sundberg, B., Arvidson, J., Ljungman, P., Lönnies, H., Nava, S., and Ringdén, O. (2007) Leukemia 21, 1733-1738.
39. MacMillan, M. L., Blazar, B. R., DeFor, T. E., and Wagner, J. E. (2009) Bone Marrow Transplant. 43, 447-454.
40. McMahon, J. M., Conroy, S., Lyons, M., Greiser, U., O'shea, C., Strappe, P., Howard, L., Murphy, M., Barry, F., and O'Brien, T. (2006) Stem Cells Dev. 15, 87-96.
41. Schmidt-Wolf, G., and Schmidt-Wolf, I. (2003) Trends Mol. Med. 9, 67-72.
42. Yuan, H., Li, J., Xin, N., Zhao, Z., and Qin, G. (2010) Mol. Biol. Rep. 37, 4023-4031.
43. Kazuo, N., Masashi, A., Norimichi, K., Watanabe, A., Ikeda, Y., Miyoshi, H., and Kurabayashi, M. (2008) Mol. Ther. 166, 1026-1032.
44. Moriscot, C., de Fraipont, F., Richard, M. J., Marchand, M., Savatier, P., Bosco, D., Favrot,M., and Benhamou, P. Y. (2005) Stem Cells 23, 594-603.
45. Gradwohl, G., Dierich, A., LeMeur, M., and Guillemot, F. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 1607-1611.