Eosinophil peroxidase induces the expression and function of acid-sensing ion channel-3 in allergic rhinitis: In vitro evidence in cultured epithelial cells

Clinical and Experimental Allergy

Volumn 42, Issue 7, 2012, Pages 1028-1039

  G Khoo, S ^a   Al Alawi, M ^a   Walsh, M T ^a   Hannigan, K ^a   Glynn, S ^a   Thornton, M ^a   McQuaid, S ^b   Wang, Y ^c   Hamilton, P W ^c   Verriere, V ^a   Gleich, G J ^d   Harvey, B J ^a   Costello, R W ^a   McGarvey, L P ^c  

^a Education and Research Centre   (Ireland)

^b ROYAL GROUP OF HOSPITALS TRUST   (United Kingdom)

^c QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Acid activated ligand gated cation channels; Acid sensing ion channels; Allergic rhinitis; Eosinophil

Indexed keywords

ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL 3; AMILORIDE; EOSINOPHIL PEROXIDASE; LACTIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 3; UNCLASSIFIED DRUG;

ADULT; ALLERGIC RHINITIS; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EOSINOPHIL; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; MALE; NASAL BIOPSY; NOSE MUCOSA; NOSE MUCUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RHINORRHEA; SECRETORY CELL;

ADOLESCENT; ADULT; BIOPSY; CELLS, CULTURED; EOSINOPHIL PEROXIDASE; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; LACTIC ACID; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NASAL MUCOSA; POLYMERASE CHAIN REACTION; RHINITIS, ALLERGIC, SEASONAL; SODIUM CHANNELS;

EID: 84862561045     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2012.03980.x     Document Type: Article

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