Asynchronous magnetic bead rotation microviscometer for rapid, sensitive, and label-free studies of bacterial growth and drug sensitivity

Analytical Chemistry

Volumn 84, Issue 12, 2012, Pages 5250-5256

  Sinn, Irene ^a   Albertson, Theodore ^a   Kinnunen, Paivo ^a   Breslauer, David N ^b   McNaughton, Brandon H ^a   Burns, Mark A ^a   Kopelman, Raoul ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b Refactored Materials Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMICROBIAL SUSCEPTIBILITY; BACTERIAL COUNT; BACTERIAL GROWTH; COMMERCIAL SYSTEMS; DRUG SENSITIVITY; DRUG SUSCEPTIBILITY; E. COLI; INITIAL CONCENTRATION; LABEL FREE; MAGNETIC BEADS; MICROBIAL STRAIN; MINIMUM INHIBITORY CONCENTRATION; UROPATHOGENIC ESCHERICHIA COLI; WIDE SPECTRUM;

ESCHERICHIA COLI;

TURNAROUND TIME;

ANTIINFECTIVE AGENT; GENTAMICIN; MICROSPHERE;

ARTICLE; DRUG EFFECT; ESCHERICHIA COLI; GROWTH, DEVELOPMENT AND AGING; INSTRUMENTATION; MAGNET; MICROTECHNOLOGY; ROTATION; TIME; VISCOSITY;

ANTI-BACTERIAL AGENTS; ESCHERICHIA COLI; GENTAMICINS; MAGNETS; MICROSPHERES; MICROTECHNOLOGY; ROTATION; TIME FACTORS; VISCOSITY;

EID: 84862555484     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac300128p     Document Type: Article

References (47)

1. Barenfanger, J.; Drake, C.; Kacich, G. Clinical and Financial Benefits of Rapid Bacterial Identification and Antimicrobial Susceptibility Testing J. Clin. Microbiol. 1999, 37, 1415-1418 (Pubitemid 29187810)
2. Chen, C. H. Antimicrobial Susceptibility Testing Using High Surface-to-Volume Ratio Microchannels Anal. Chem. 2010, 82, 1012-1019
3. Martinez, J. L. A global view of antibiotic resistance FEMS Microbiol. Rev. 2009, 33, 44-65
4. Costelloe, C.; Metcalfe, C.; Lovering, A.; Mant, D.; Hay, A. D. Effect of antibiotic prescribing in primary care on antimicrobial resistance in individual patients: systematic review and meta-analysis BMJ 2010, 340, c2096-c2096
5. Alvarez-Lerma, F. Empiric broad-spectrum antibiotic therapy of nosocomial pneumonia in the intensive care unit: a prospective observational study Crit. Care 2006, 10, R78
6. Mach, K. E. A Biosensor Platform for Rapid Antimicrobial Susceptibility Testing Directly From Clinical Samples J. Urol. 2011, 185, 148-153
7. Jorgensen, J. H.; Ferraro, M. J. Antimicrobial Susceptibility Testing: General Principles and Contemporary Practices Clin. Infect. Dis. 1998, 26, 973-980 (Pubitemid 28180340)
8. Jorgensen, J. H.; Ferraro, M. J. Medical Microbiology: Antimicrobial Susceptibility Testing: A Review of General Principles and Contemporary Practices Clin. Infect. Dis. 2009, 49, 1749-1755
9. Goldman, E.; Green, L. H. Practical Handbook of Microbiology; CRC Press: 2008.
10. Health, C. for D. and R. Guidance Documents (Medical Devices and Radiation-Emitting Products)-Class II Special Controls Guidance Document: Antimicrobial Susceptibility Test (AST) Systems. At < http://www.fda.gov/ MedicalDevices/DeviceRegulationandGuidance/GuidanceDocuments/ucm080564.htm > (accessed May 9, 2012).
11. Andrews, J. M. Determination of minimum inhibitory concentrations J. Antimicrob. Chemother. 2001, 48, 5
12. Boedicker, J. Q.; Li, L.; Kline, T. R.; Ismagilov, R. F. Detecting bacteria and determining their susceptibility to antibiotics by stochastic confinement in nanoliter droplets using plug-based microfluidics Lab Chip 2008, 8, 1265
13. Kinnunen, P. Monitoring the growth and drug susceptibility of individual bacteria using asynchronous magnetic bead rotation sensors Biosens. Bioelectron. 2011, 26, 2751-2755
14. Sinn, I. Asynchronous magnetic bead rotation (AMBR) biosensor in microfluidic droplets for rapid bacterial growth and susceptibility measurements Lab Chip 2011, 11, 2604
15. Boedicker, J. Q.; Vincent, M. E.; Ismagilov, R. F. Microfluidic Confinement of Single Cells of Bacteria in Small Volumes Initiates High-Density Behavior of Quorum Sensing and Growth and Reveals Its Variability13 Angew. Chem. 2009, 121, 6022-6025
16. Ong, K. G.; Wang, J.; Singh, R. S.; Bachas, L. G.; Grimes, C. A. Monitoring of bacteria growth using a wireless, remote query resonant-circuit sensor: application to environmental sensing Biosens. Bioelectron. 2001, 16, 305-312 (Pubitemid 32522790)
17. Rafaï, S.; Jibuti, L.; Peyla, P. Effective Viscosity of Microswimmer Suspensions Phys. Rev. Lett. 2010, 104, 098102
18. Stoyanov, P. G.; Grimes, C. A. A remote query magnetostrictive viscosity sensor Sens. Actuators, A 2000, 80, 8-14 (Pubitemid 30556993)
19. Sokolov, A.; Aranson, I. S. Reduction of Viscosity in Suspension of Swimming Bacteria Phys. Rev. Lett. 2009, 103, 148101
20. Cui, Z. Weakly sheared active suspensions: hydrodynamics, stability, and rheology Phys. Rev. E: Stat., Nonlinear, Soft Matter Phys. 2011, 83, 031911
21. Hatwalne, Y.; Ramaswamy, S.; Rao, M.; Simha, R. A. Rheology of Active-Particle Suspensions Phys. Rev. Lett. 2004, 92, 118101
22. Saintillan, D.; Shelley, M. J. Instabilities and pattern formation in active particle suspensions: kinetic theory and continuum simulations Phys. Rev. Lett. 2008, 100, 178103
23. Toda, K.; Furuse, H.; Amari, T.; Wei, X. Cell concentration dependence of dynamic viscoelasticity of Escherichia coli culture suspensions J. Ferment. Bioeng. 1998, 85, 410-415 (Pubitemid 28215747)
24. Suresh Kumar, A.; Mody, K.; Jha, B. Bacterial exopolysaccharides - a perception J. Basic Microbiol. 2007, 47, 103-117 (Pubitemid 46953809)
25. Furuse, H.; Amari, T.; Miyawaki, O.; Asakura, T.; Toda, K. Characteristic behavior of viscosity and viscoelasticity of Aureobasidium pullulans culture fluid J. Biosci. Bioeng. 2002, 93, 411-415 (Pubitemid 34971761)
26. Sutherland, I. W. Biofilm exopolysaccharides: a strong and sticky framework Microbiology 2001, 147, 3-9 (Pubitemid 32094304)
27. Pang, P.; Cai, Q.; Yao, S.; Grimes, C. A. The detection of Mycobacterium tuberculosis in sputum sample based on a wireless magnetoelastic-sensing device Talanta 2008, 76, 360-364
28. Kinnunen, P.; Sinn, I.; McNaughton, B. H.; Kopelman, R. High frequency asynchronous magnetic bead rotation for improved biosensors Appl. Phys. Lett. 2010, 97, 223701
29. McNaughton, B. H.; Agayan, R. R.; Clarke, R.; Smith, R. G.; Kopelman, R. Single bacterial cell detection with nonlinear rotational frequency shifts of driven magnetic microspheres Appl. Phys. Lett. 2007, 91, 224105
30. McNaughton, B. H.; Agayan, R. R.; Wang, J. X.; Kopelman, R. Physiochemical microparticle sensors based on nonlinear magnetic oscillations Sens. Actuators, B 2007, 121, 330-340 (Pubitemid 46123907)
31. McNaughton, B. H.; Kehbein, K. A.; Anker, J. N.; Kopelman, R. Sudden Breakdown in Linear Response of a Rotationally Driven Magnetic Microparticle and Application to Physical and Chemical Microsensing J. Phys. Chem. B 2006, 110, 18958-18964 (Pubitemid 44547282)
32. McNaughton, B. H. Compact sensor for measuring nonlinear rotational dynamics of driven magnetic microspheres with biomedical applications J. Magn. Magn. Mater. 2009, 321, 1648-1652
33. Hecht, A.; Kinnunen, P.; McNaughton, B.; Kopelman, R. Label-acquired magnetorotation for biosensing: An asynchronous rotation assay J. Magn. Magn. Mater. 2011, 323, 272-278
34. Hecht, A.; Kumar, A. A.; Kopelman, R. Label-Acquired Magnetorotation As a Signal Transduction Method for Protein Detection: Aptamer-Based Detection of Thrombin Anal. Chem. 2011, 83, 7123-7128
35. Behrend, A. J.; McNaughton, B.; Kopelman, R. Microrheology with modulated optical nanoprobes (MOONs) J. Magn. Magn. Mater. 2005, 293, 663-670 (Pubitemid 40608993)
36. Riesch, C.; Reichel, E. K.; Keplinger, F.; Jakoby, B. Characterizing Vibrating Cantilevers for Liquid Viscosity and Density Sensing J. Sens. 2008, 697062
37. Kuntner, J.; Stangl, G.; Jokoby, B. Characterizing the rheological behavior of oil-based liquids: microacoustic sensors versus rotational viscometers Sens. J., IEEE 2005, 5, 850-856 (Pubitemid 41583921)
38. Sanchez, F. G.; Diaz, A. N.; Ruiz, C. C.; Guerrero, M. M. L. Fluid viscosity determination based on frequency domain time-resolved fluorescence anisotropy J. Mol. Liq. 2010, 155, 121-126
39. Pal, R. An integrated microfluidic device for influenza and other genetic analyses Lab Chip 2005, 5, 1024-1032 (Pubitemid 41452991)
40. Sinn, I. Magnetically uniform and tunable Janus particles Appl. Phys. Lett. 2011, 98, 024101
41. McNaughton, B. H. Fabrication of Nanoparticles and Microspheres with Uniform Magnetic Half-Shells. MRS Proceedings, 899E 988, (2006).
42. Anker, J. N.; Kopelman, R. Magnetically modulated optical nanoprobes Appl. Phys. Lett. 2003, 82, 1102
43. Shankar, P. N.; Kumar, M. Experimental Determination of the Kinematic Viscosity of Glycerol-Water Mixtures Proc. R. Soc. London, Ser. A 1994, 444, 573-581 (Pubitemid 280659)
44. Sakai, K.; Hirano, T.; Hosoda, M. Electromagnetically Spinning Sphere Viscometer Appl. Phys. Express 2010, 3, 016602
45. Hosoda, M.; Hirano, T.; Sakai, K. Extension of Measurement Viscosity Range of EMS System Proc. Symp. Ultrasonic Electronics 2010, 31, 293-294
46. D'Avino, G.; Cicale, G.; Hulsen, M. A.; Greco, F.; Maffettone, P. L. Effects of confinement on the motion of a single sphere in a sheared viscoelastic liquid J. Non-Newtonian Fluid Mech. 2009, 157, 101-107
47. Teyssandier, F.; Love, B. J. MMA bulk polymerization and its influence on in situ resin viscosity comparing several chemorheological models J. Appl. Polym. Sci. 2011, 120, 1367-1371