Increased unbound drug fraction in acute carbamazepine intoxication: Suitability and effectiveness of high-flux haemodialysis

Intensive Care Medicine

Volumn 38, Issue 5, 2012, Pages 916-917

  Sikma, M A ^a   Broek, M P H Van Den ^a   Meulenbelt, J ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED CARBON; AMIODARONE; CARBAMAZEPINE;

ADULT; CASE REPORT; COMA; DRUG BLOOD LEVEL; DRUG INTOXICATION; DRUG OVERDOSE; EPILEPSY; FEMALE; HEART VENTRICLE FIBRILLATION; HEMODIALYSIS; HIGH FLUX HEMODIALYSIS; HUMAN; INTENSIVE CARE UNIT; LETTER; MORTALITY; OUTCOME ASSESSMENT; RESUSCITATION; SHOCK;

ANTICONVULSANTS; CARBAMAZEPINE; DRUG OVERDOSE; DRUG TOXICITY; FEMALE; HUMANS; INTENSIVE CARE UNITS; MIDDLE AGED; RENAL DIALYSIS; TREATMENT OUTCOME;

EID: 84862545395     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-012-2501-8     Document Type: Letter

References (4)

1. Garlich FM, Goldfarb DS (2011) Have advances in extracorporeal removal techniques changed the indications for their use in poisonings? Adv Chronic Kidney Dis 18:172-179
2. Bek K, Kocak S, Ozkaya O, Yilmaz Y, Aydin OF, Tasdoven CS (2007) Carbamazepine poisoning managed with haemodialysis and haemoperfusion in three adolescents. Nephrology (Carlton) 12:33-35
3. Tapolyai M, Campbell M, Dailey K, Udvari-Nagy S (2002) Hemodialysis is as effective as hemoperfusion for drug removal in carbamazepine poisoning. Nephron 90:213-215
4. Mouly S, Meune C, Bergmann JF (2009) Mini-series: I. Basic science. Uncertainty and inaccuracy of predicting CYPmediated in vivo drug interactions in the ICU from in vitro models: focus on CYP3A4. Intensive Care Med 35:417-429