Tissue-to-cellular deformation coupling in cell-microintegrated elastomeric scaffolds

IUTAM Bookseries

Volumn 16, Issue , 2010, Pages 81-89

  Stella, J A ^a   Liao, J ^a,b   Hong, Y ^c,d   Merryman, W D ^a,e   Wagner, W R ^a,b,c   Sacks, M S ^a,b  

^a Department of Bioengineering ^*  (United States)

^b MISSISSIPPI STATE UNIVERSITY   (United States)

^c MCGOWAN INSTITUTE FOR REGENERATIVE MEDICINE   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APPLIED STRAIN; BIAXIAL STRETCH; CELL FUNCTIONS; CELLULAR DEFORMATION; CHEMICAL FACTORS; DEFORMATION COUPLINGS; DEFORMATION RESPONSE; ELASTOMERIC SCAFFOLDS; ENGINEERED TISSUES; FIBROUS SCAFFOLDS; MICRO ARCHITECTURES; MICROSTRUCTURAL CHANGES; NONLINEAR DEFORMATIONS; TISSUE DEVELOPMENT; TISSUE GROWTH; TISSUE REMODELING; TISSUE REPLACEMENT; VASCULAR SMOOTH MUSCLE CELLS;

CELL PROLIFERATION; CELLS; CYTOLOGY; DEFORMATION; THREE DIMENSIONAL; TISSUE;

SCAFFOLDS (BIOLOGY);

EID: 84862537075     PISSN: 18753507     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-90-481-3348-2_7     Document Type: Conference Paper

References (15)

1. Stella JA, Liao J, Hong Y, David Merryman W, Wagner WR, Sacks MS (2008) Tissue-tocellular level deformation coupling in cell micro-integrated elastomeric scaffolds. Biomaterials 29:3228.
2. Stella JA, Wagner WR, Sacks MS (in press) Scale dependent fiber kinematics of elastomeric electrospun scaffolds for soft tissue engineering. J Biomed Mater Res.
3. Stankus JJ, Soletti L, Fujimoto K, Hong Y, Vorp DA, Wagner WR (2007) Fabrication of cell microintegrated blood vessel constructs through electrohydrodynamic atomization. Biomaterials 28:2738.
4. Stankus JJ, Guan J, Wagner WR (2004) Fabrication of biodegradable elastomeric scaffolds with sub-micron morphologies. J Biomed Mater Res 70A:603.
5. Stankus JJ, Guan J, Fujimoto K, Wagner WR (2006) Microintegrating smooth muscle cells into a biodegradable, elastomeric fiber matrix. Biomaterials 27:735.
6. Zhong S, Teo WE, Zhu X, Beuerman RW, Ramakrishna S, Yung LY (2006) An aligned nanofibrous collagen scaffold by electrospinning and its effects on in vitro fibroblast culture. J Biomed Mater Res A 79:456.
7. Nerurkar NL, Elliott DM, Mauck RL (2007) Mechanics of oriented electrospun nanofibrous scaffolds for annulus fibrosus tissue engineering. J Orthop Res 25:1018.
8. Courtney T, Sacks MS, Stankus J, Guan J, Wagner WR (2006) Design and analysis of tissue engineering scaffolds that mimic soft tissue mechanical anisotropy. Biomaterials 27:3631.
9. Chaudhuri BB, Kundu P, Sarkar N (1993) Detection and gradation of oriented texture. Pattern Recogn Lett 14:147.
10. Karlon WJ, Covell JW, McCulloch AD, Hunter JJ, Omens JH (1998) Automated measurement of myofiber disarray in transgenic mice with ventricular expression of ras. Anat Rec 252:612.
11. Huang HY, Liao J, Sacks MS (2007) In-situ deformation of the aortic valve interstitial cell nucleus under diastolic loading. J Biomech Eng 129:880.
12. Johnson J, Anirban A, Lannutti J (2007) Microstructure-property relationships in a tissueengineering scaffold. J Appl Poly Sci 104:2919.
13. Freed LE, Vunjak-Novakovic G, Biron RJ, Eagles DB, Lesnoy DC, Barlow SK, Langer R (1994) Biodegradable polymer scaffolds for tissue engineering. Nat Biotechnol 12:689.
14. Engelmayr GC, Jr, Sales VL, Mayer JE, Jr, Sacks MS (2006) Cyclic flexure and laminar flow synergistically accelerate mesenchymal stem cell-mediated engineered tissue formation: Implications for engineered heart valve tissues. Biomaterials 27:6083.
15. Engelmayr GC, Jr, Sacks MS (2008) Prediction of extracellular matrix stiffness in engineered heart valve tissues based on nonwoven scaffolds. Biomech Model Mechanobiol 7:309.