Assessment and validation of US EPA's OncoLogic® expert system and analysis of its modulating factors for structural alerts

Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology Reviews

Volumn 30, Issue 2, 2012, Pages 152-173

  Benigni, Romualdo ^a   Bossa, Cecilia ^a   Alivernini, Silvia ^a   Colafranceschi, Mauro ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Carcinogens; Potency; Predictive toxicology; Structural alert; Structure activity

Indexed keywords

MODULATING FACTOR; POTENCY; PREDICTIVE TOXICOLOGY; PREDICTIVITY; SOFTWARE PROGRAM; STRUCTURAL ALERT; STRUCTURE-ACTIVITY; STRUCTURE-ACTIVITY RELATIONSHIPS; TOXICOLOGICAL EFFECTS;

BIOASSAY; CARCINOGENS; CHEMICAL COMPOUNDS; EXPERT SYSTEMS; MAMMALS; STRUCTURAL ANALYSIS;

FACTOR ANALYSIS;

CARCINOGEN;

AMES TEST; ARTICLE; BIOASSAY; CARCINOGENICITY; CHEMICAL CARCINOGENESIS; CHEMICAL STRUCTURE; COMPUTER PROGRAM; CORRELATION ANALYSIS; DATA BASE; ECOTOXICOLOGY; ENVIRONMENTAL PROTECTION; EXPERT SYSTEM; GOVERNMENT; HEALTH HAZARD; MOUSE; NONHUMAN; PREDICTIVE VALUE; RAT; RODENT; STRUCTURE ACTIVITY RELATION; UNITED STATES; VALIDATION STUDY;

ANIMALS; BIOLOGICAL ASSAY; CARCINOGENICITY TESTS; CARCINOGENS; EXPERT SYSTEMS; MICE; PREDICTIVE VALUE OF TESTS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; UNITED STATES; UNITED STATES ENVIRONMENTAL PROTECTION AGENCY;

EID: 84862528518     PISSN: 10590501     EISSN: 15324095     Source Type: Journal    
DOI: 10.1080/10590501.2012.681486     Document Type: Article

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