Implementation of an intensive risk-stratified treatment protocol for children and adolescents with acute lymphoblastic leukemia in Lebanon

American Journal of Hematology

Volumn 87, Issue 7, 2012, Pages 678-683

  Muwakkit, Samar ^a   Al Aridi, Carol ^a   Samra, Ahmad ^a   Saab, Raya ^a   Mahfouz, Rami A ^a   Farra, Chantal ^a   Jeha, Sima ^b   Abboud, Miguel R ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHYPERTENSIVE AGENT; ASPARAGINASE; CIDOFOVIR; CYCLOPHOSPHAMIDE; CYTARABINE; DAUNORUBICIN; DEXAMETHASONE; DOXORUBICIN; FOSCARNET; GANCICLOVIR; IMATINIB; MERCAPTOPURINE; METHOTREXATE; PREDNISONE; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADOLESCENT DISEASE; ADULT; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ARTICLE; ASPERGILLOSIS; BONE MARROW BIOPSY; BONE MARROW METASTASIS; CANCER COMBINATION CHEMOTHERAPY; CANCER MORTALITY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CELLULITIS; CENTRAL NERVOUS SYSTEM LEUKEMIA; CHICKENPOX; CHILD; CHILDHOOD LEUKEMIA; CLOSTRIDIUM DIFFICILE INFECTION; COMPLEX PARTIAL SEIZURE; CYTOMEGALOVIRUS INFECTION; CYTOMEGALOVIRUS RETINITIS; DIARRHEA; DOWN SYNDROME; DRUG MEGADOSE; DRUG SAFETY; DRUG WITHDRAWAL; ERYTHROCYTE CONCENTRATE; ERYTHROCYTE TRANSFUSION; EVENT FREE SURVIVAL; FEBRILE NEUTROPENIA; FEMALE; FEVER; FOLLOW UP; GIARDIASIS; GRAM NEGATIVE SEPSIS; GRAM POSITIVE INFECTION; HERPES ZOSTER; HUMAN; HUMAN TISSUE; HYPERTENSION; INAPPROPRIATE VASOPRESSIN SECRETION; INFANT; INFLUENZA A; LEBANON; LEG THROMBOSIS; LEUKEMIA RELAPSE; LEUKEMIA REMISSION; MAJOR CLINICAL STUDY; MALE; MULTIMODALITY CANCER THERAPY; NECROTIZING FASCIITIS; NEUTROPENIA; ORBIT CELLULITIS; OTITIS MEDIA; OVERALL SURVIVAL; PANCREATITIS; PHILADELPHIA CHROMOSOME POSITIVE CELL; PNEUMONIA; POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME; PRESCHOOL CHILD; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; RISK ASSESSMENT; ROTAVIRUS INFECTION; SCHOOL CHILD; SEPTIC SHOCK; SEX RATIO; SINUSITIS; SOCIAL STATUS; SURVIVAL RATE; TUMOR LYSIS SYNDROME; TYPHLITIS; VIREMIA; VIRUS PNEUMONIA;

ADOLESCENT; ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CANCER CARE FACILITIES; CHILD; CHILD, PRESCHOOL; DEVELOPING COUNTRIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; LEBANON; MALE; OPPORTUNISTIC INFECTIONS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROGNOSIS; RECURRENCE; REMISSION INDUCTION; SURVIVAL ANALYSIS; YOUNG ADULT;

EID: 84862520884     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.23222     Document Type: Article

References (32)

1. Stanulla M, Schrappe M. Treatment of childhood acute lymphoblastic leukemia. Semin Hematol 2009; 46: 52-63.
2. Gurney JG, Severson RK, Davis S, et al. Incidence of cancer in children in the United States. Sex-, race-, and 1-year age-specific rates by histologic type. Cancer 1995; 75: 2186-2195.
3. Steliarova-Foucher E, Stiller C, Kaatsch P, et al. Geographical patterns and time trends of cancer incidence and survival among children and adolescents in Europe since the 1970s (the ACCISproject): an epidemiological study. Lancet 2004; 364: 2097-2105.
4. Pui CH, Evans WE. Treatment of acute lymphoblastic leukemia. N Engl J Med 2006; 354: 166-178.
5. Arico M, Valsecchi MG, Rizzari C, et al. Long-term results of the AIEOP-ALL-95 Trial for Childhood Acute Lymphoblastic Leukemia: Insight on the prognostic value of DNA index in the framework of Berlin-Frankfurt-Muenster based chemotherapy. J Clin Oncol 2008; 26: 283-289.
6. Gaynon PS, Trigg ME, Heerema NA, et al. Children's Cancer Group trials in childhood acute lymphoblastic leukemia: 1983-1995. Leukemia 2000; 14: 2223-2233.
7. Pui CH, Sandlund JT, Pei D, et al. Improved outcome for children with acute lymphoblastic leukemia: results of Total Therapy Study XIIIB at St Jude Children's Research Hospital. Blood 2004; 104: 2690-2696.
8. Moricke A, Reiter A, Zimmermann M, et al. Risk-adjusted therapy of acute lymphoblastic leukemia can decrease treatment burden and improve survival: Treatment results of 2169 unselected pediatric and adolescent patients enrolled in the trial ALL-BFM 95. Blood 2008; 111: 4477-4489.
9. Campbell M, Salgado C, Quintana J, et al. Improved outcome for acute lymphoblastic leukemia in children of a developing country: Results of the Chilean National Trial PINDA 87. Med Pediatr Oncol 1999; 33: 88-94.
10. Bonilla M, Moreno N, Marina N, et al. Acute lymphoblastic leukemia in a developing country: preliminary results of a nonrandomized clinical trial in El Salvador. J Pediatr Hematol Oncol 2000; 22: 495-501.
11. Magrath I, Shanta V, Advani S, et al. Treatment of acute lymphoblastic leukaemia in countries with limited resources; lessons from use of a single protocol in India over a twenty year period [corrected]. Eur J Cancer 2005; 41: 1570-1583.
12. Dabbous IA, Dbouk H, Sibai AM, et al. Childhood acute lymphoblastic leukemia managed in tertiary care center in a developing country. Med Pediatr Oncol 2003; 41: 83-84.
13. Bitar J. Acute leukemia in childhood. J Med Liban 1970; 23: 223-231.
14. Pui CH, Campana D, Pei D, et al. Treating childhood acute lymphoblastic leukemia without cranial irradiation. N Engl J Med 2009; 360: 2730-2741.
15. Bennett JM, Catovsky D, Daniel MT, et al. Proposals for the classification of the acute leukaemias. French-American-British (FAB) co-operative group. Br J Haematol 1976; 33: 451-458.
16. Coustan-Smith E, Ribeiro RC, Stow P, et al. A simplified flow cytometric assay identifies children with acute lymphoblastic leukemia who have a superior clinical outcome. Blood 2006; 108: 97-102.
17. Kaplan E, Meier P. Non-parametric estimation from in complete observations. J Am Stat Assoc 1958; 53: 457-481.
18. Advani S, Pai S, Venzon D, et al. Acute lymphoblastic leukemia in India: An analysis of prognostic factors using a single treatment regimen. Ann Oncol 1999; 10: 167-176.
19. Pui CH, Pei D, Sandlund JT, et al. Long-term results of St Jude Total Therapy Studies 11, 12, 13A, 13B, and 14 for childhood acute lymphoblastic leukemia. Leukemia 2010; 24: 371-382.
20. Bajel A, George B, Mathews V, et al. Treatment of children with acute lymphoblastic leukemia in India using a BFM protocol. Pediatr Blood Cancer 2008; 51: 621-625.
21. Hussein H, Sidhom I, Naga SA, et al. Outcome and prognostic factors of acute lymphoblastic leukemia in children at the National Cancer Institute, Egypt. J Pediatr Hematol Oncol 2004; 26: 507-514.
22. Halalsheh H, Abuirmeileh N, Rihani R, et al. Outcome of childhood acute lymphoblastic leukemia in Jordan. Pediatr Blood Cancer 2011; 57: 385-391.
23. Shing MM, Li CK, Chik KW, et al. Outcomes and prognostic factors of Chinese children with acute lymphoblastic leukemia in Hong Kong: Preliminary results. Med Pediatr Oncol 1999; 32: 117-123.
24. Hunger SP, Sung L, Howard SC. Treatment strategies and regimens of graduated intensity for childhood acute lymphoblastic leukemia in low-income countries: A proposal. Pediatr Blood Cancer 2009; 52: 559-565.
25. Pui CH, Ribeiro RC. International collaboration on childhood leukemia. Int J Hematol 2003; 78: 383-389.
26. Howard SC, Pedrosa M, Lins M, et al. Establishment of a pediatric oncology program and outcomes of childhood acute lymphoblastic leukemia in a resource-poor area. JAMA 2004; 291: 2471-2475.
27. Liu Y, Chen J, Tang J, et al. Cost of childhood acute lymphoblastic leukemia care in Shanghai, China. Pediatr Blood Cancer 2009; 53: 557-562.
28. Pui CH, Boyett JM, Rivera GK, et al. Long-term results of Total Therapy studies 11, 12 and 13A for childhood acute lymphoblastic leukemia at St Jude Children's Research Hospital. Leukemia 2000; 14: 2286-2294.
29. Schrappe M, Reiter A, Zimmermann M, et al. Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995. Berlin-Frankfurt-Munster. Leukemia 2000; 14: 2205-2222.
30. Kulkarni KP, Marwaha RK, Trehan A, et al. Survival outcome in childhood ALL: Experience from a tertiary care centre in North India. Pediatr Blood Cancer 2009; 53: 168-173.
31. Stark B, Nirel R, Avrahami G, et al. Long-term results of the Israeli National Studies in childhood acute lymphoblastic leukemia: INS 84, 89 and 98. Leukemia 2010; 24: 419-424.
32. El-Hajj Fuleihan G, Muwakkit S, Arabi A, et al. Predictors of bone loss in childhood hematologic malignancies: a prospective study. Osteoporos Int 2012; 23: 665-674.