The molecular role of Fra-1 and its prognostic significance in human esophageal squamous cell carcinoma

Cancer

Volumn 118, Issue 13, 2012, Pages 3387-3396

  Usui, Akihiro ^a   Hoshino, Isamu ^a   Akutsu, Yasunori ^a   Sakata, Haruhito ^a   Nishimori, Takanori ^a   Murakami, Kentaro ^a   Kano, Masayuki ^a   Shuto, Kiyohiko ^a   Matsubara, Hisahiro ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

Cell invasion; Cell migration; Cell proliferation; Esophageal squamous cell carcinoma; Fra 1; Prognosis

Indexed keywords

TRANSCRIPTION FACTOR FRA 1;

ADULT; AGED; ARTICLE; CANCER GROWTH; CANCER INFILTRATION; CANCER INHIBITION; CANCER LOCALIZATION; CANCER PATIENT; CANCER STAGING; CANCER SURVIVAL; CARCINOMA CELL; CELL INVASION; CELL MOTILITY; CELL PROLIFERATION; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; DOWN REGULATION; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DISEASE PROGRESSION; DOWN-REGULATION; ESOPHAGEAL NEOPLASMS; FEMALE; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; PROGNOSIS; PROTO-ONCOGENE PROTEINS C-FOS; SURVIVAL ANALYSIS;

EID: 84862519600     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.26652     Document Type: Article

References (28)

1. Courrech Staal EF, van Coevorden F, Cats A, et al. Outcome of low-volume surgery for esophageal cancer in a high-volume referral center. Ann Surg Oncol. 2009; 16: 3219-3226.
2. Law SY, Fok M, Cheng SW, Wong J,. A comparison of outcome after resection for squamous cell carcinomas and adenocarcinomas of the esophagus and cardia. Surg Gynecol Obstet. 1992; 175: 107-112.
3. Mehlen P, Puisieux A,. Metastasis: a question of life or death. Nat Rev Cancer. 2006; 6: 449-458.
4. Curran T, Franza BR Jr,. Fos and Jun: the AP-1 connection. Cell. 1988; 55: 395-397. (Pubitemid 18261431)
5. Angel P, Karin M,. Specific members of the Jun protein family regulate collagenase expression in response to various extracellular stimuli. Matrix Suppl. 1992; 1: 156-164.
6. Eferl R, Wagner EF,. AP-1: a double-edged sword in tumorigenesis. Nat Rev Cancer. 2003; 3: 859-868. (Pubitemid 37383716)
7. Mechta F, Lallemand D, Pfarr CM, Yaniv M,. Transformation by ras modifies AP1 composition and activity. Oncogene. 1997; 14: 837-847. (Pubitemid 27100028)
8. Vial E, Sahai E, Marshall CJ,. ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility. Cancer Cell. 2003; 4: 67-79. (Pubitemid 36904162)
9. Kakumoto K, Sasai K, Sukezane T, et al. FRA1 is a determinant for the difference in RAS-induced transformation between human and rat fibroblasts. Proc Natl Acad Sci U S A. 2006; 103: 5490-5495.
10. Hu YC, Lam KY, Law S, Wong J, Srivastava G,. Identification of differentially expressed genes in esophageal squamous cell carcinoma (ESCC) by cDNA expression array: overexpression of Fra-1, Neogenin, Id-1, and CDC25B genes in ESCC. Clin Cancer Res. 2001; 7: 2213-2221. (Pubitemid 32751617)
11. Ramos-Nino ME, Scapoli L, Martinelli M, Land S, Mossman BT,. Microarray analysis and RNA silencing link fra-1 to cd44 and c-met expression in mesothelioma. Cancer Res. 2003; 63: 3539-3545. (Pubitemid 36793033)
12. Hapke S, Kessler H, Luber B, et al. Ovarian cancer cell proliferation and motility is induced by engagement of integrin alpha(v)beta3/Vitronectin interaction. Biol Chem. 2003; 384: 1073-1083. (Pubitemid 37062968)
13. Kustikova O, Kramerov D, Grigorian M, et al. Fra-1 induces morphological transformation and increases in vitro invasiveness and motility of epithelioid adenocarcinoma cells. Mol Cell Biol. 1998; 18: 7095-7105. (Pubitemid 28533029)
14. Kim YH, Oh JH, Kim NH, et al. Fra-1 expression in malignant and benign thyroid tumor. Korean J Intern Med. 2001; 16: 93-97.
15. Mangone FR, Brentani MM, Nonogaki S, et al. Overexpression of Fos-related antigen-1 in head and neck squamous cell carcinoma. Int J Exp Pathol. 2005; 86: 205-212. (Pubitemid 41074385)
16. Zhang W, Hart J, McLeod HL, Wang HL,. Differential expression of the AP-1 transcription factor family members in human colorectal epithelial and neuroendocrine neoplasms. Am J Clin Pathol. 2005; 124: 11-19. (Pubitemid 40944368)
17. Zerbini LF, Wang Y, Cho JY, Libermann TA,. Constitutive activation of nuclear factor kappaB p50/p65 and Fra-1 and JunD is essential for deregulated interleukin 6 expression in prostate cancer. Cancer Res. 2003; 63: 2206-2215. (Pubitemid 36538628)
18. Mann B, Gelos M, Siedow A, et al. Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas. Proc Natl Acad Sci U S A. 1999; 96: 1603-1608. (Pubitemid 29098498)
19. Fung LF, Lo AK, Yuen PW, Liu Y, Wang XH, Tsao SW,. Differential gene expression in nasopharyngeal carcinoma cells. Life Sci. 2000; 67: 923-936. (Pubitemid 30491086)
20. Risse-Hackl G, Adamkiewicz J, Wimmel A, Schuermann M,. Transition from SCLC to NSCLC phenotype is accompanied by an increased TRE-binding activity and recruitment of specific AP-1 proteins. Oncogene. 1998; 16: 3057-3068. (Pubitemid 28297728)
21. Debinski W, Gibo DM,. Fos-related antigen 1 modulates malignant features of glioma cells. Mol Cancer Res. 2005; 3: 237-249. (Pubitemid 40525334)
22. Sobin LH, Wittekind C, editors. TNM Classification of Malignant Tumors. 6th ed. New York, NY: John Wiley & Sons; 2002.
23. Takahashi K, Kanazawa H, Chan C-T, Hosono T, Takahara M, Sato K,. A case of esophageal carcinoma metastatic to the mandible and characterization of 2 cell lines (T.T and T. Tn) established from the oral tumor. Jpn J Oral Maxillofac Surg. 1990; 36: 67-76.
24. Nishihira T, Kasai M, Mori S, et al. Characteristics of 2 cell lines (TE-1 and TE-2) derived from human squamous cell carcinoma of the esophagus. Gann. 1979; 70: 575-584. (Pubitemid 10139660)
25. Sakai T, Furihata T, Kawamata H, et al. Molecular and genetic characterization of a non-metastatic human esophageal cancer cell line, T Tn expressing non-functional mutated p53. Int J Oncol. 2002; 21: 547-552.
26. Patterson T, Vuong H, Liaw YS, Wu R, Kalvakolanu DV, Reddy SP,. Mechanism of repression of squamous differentiation marker, SPRR1B, in malignant bronchial epithelial cells: role of critical TRE-sites and its transacting factors. Oncogene. 2001; 20: 634-644. (Pubitemid 32156188)
27. Liotta LA, Kohn EC,. The microenvironment of the tumour-host interface. Nature. 2001; 411: 375-379.
28. Adiseshaiah P, Lindner DJ, Kalvakolanu DV, Reddy SP,. FRA-1 proto-oncogene induces lung epithelial cell invasion and anchorage-independent growth in vitro, but is insufficient to promote tumor growth in vivo. Cancer Res. 2007; 67: 6204-6211. (Pubitemid 47037501)