Effect of propofol on vascular reactivity in thoracic aortas from rats with endotoxemia

Journal of the Chinese Medical Association

Volumn 75, Issue 6, 2012, Pages 262-268

  Tsao, Cheng Ming ^a   Chen, Shiu Jen ^b   Tsou, Mei Yung ^a   Wu, Chin Chen ^c  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b Kang Ning Junior College of Medical Care and Management   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

Calcium influx; Nitric oxide; Propofol; Sepsis; Vascular smooth muscle

Indexed keywords

ACETYLCHOLINE; GUANYLATE CYCLASE INHIBITOR; NITRIC OXIDE SYNTHASE INHIBITOR; NORADRENALIN; PROPOFOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DRUG EFFECT; ENDOTOXEMIA; MALE; NONHUMAN; RAT; THORACIC AORTA; VASCULAR RING; VASODILATATION;

ANIMALS; AORTA, THORACIC; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTOXEMIA; LIPOPOLYSACCHARIDES; MALE; NITRIC OXIDE; NOREPINEPHRINE; PROPOFOL; RATS; RATS, WISTAR; VASOCONSTRICTION;

EID: 84862509504     PISSN: 17264901     EISSN: 17287731     Source Type: Journal    
DOI: 10.1016/j.jcma.2012.04.009     Document Type: Article

References (35)

1. Thiemermann C. The role of the L-arginine: nitric oxide pathway in circulatory shock. Adv Pharmacol 1994, 28:45-79.
2. +-ATPase in rat aortas: pharmacological and functional evidence. Chin J Physiol 2005, 48:86-92.
3. + pump in aortas from rats with endotoxaemia. Naunyn Schmiedebergs Arch Pharmacol 2003, 368:57-62.
4. Kuo J.H., Chen S.J., Shih C.C., Lue W.M., Wu C.C. Abnormal activation of potassium channels in aortic smooth muscle of rats with peritonitis-induced septic shock. Shock 2009, 32:74-79.
5. Pagel P.S., Warltier D.C. Negative inotropic effects of propofol as evaluated by the regional preload recruitable stroke work relationship in chronically instrumented dogs. Anesthesiology 1993, 78:100-108.
6. Shafer S.L. Advances in propofol pharmacokinetics and pharmacodynamics. J Clin Anesth 1993, 5:14S-21.
7. Claeys M.A., Gepts E., Camu F. Haemodynamic changes during anaesthesia induced and maintained with propofol. Br J Anaesth 1988, 60:3-9.
8. Rouby J.J., Andreev A., Léger P., Arthaud M., Landault C., Vicaut E., et al. Peripheral vascular effects of thiopental and propofol in humans with artificial hearts. Anesthesiology 1991, 75:32-42.
9. Robinson B.J., Ebert T.J., O'Brien T.J., Colinco M.D., Muzi M. Mechanisms whereby propofol mediates peripheral vasodilation in humans: sympathoinhibition or direct vascular relaxation?. Anesthesiology 1997, 86:64-72.
10. Biddle N.L., Gelb A.W., Hamilton J.T. Propofol differentially attenuates the responses to exogenous and endogenous norepinephrine in the isolated rat femoral artery in vitro. Anesth Analg 1995, 80:793-799.
11. Gelb A.W., Zhang C., Hamilton J.T. Propofol induces dilation and inhibits constriction in guinea pig basilar arteries. Anesth Analg 1996, 83:472-476.
12. Park W.K., Lynch C., Johns R.A. Effects of propofol and thiopental in isolated rat aorta and pulmonary artery. Anesthesiology 1992, 77:956-963.
13. Forstermann U., Schmidt H.H., Pollock J.S., Sheng H., Mitchell J.A., Warner T.D., et al. Isoforms of nitric oxide synthase:characterization and purification from different cell types. Biochem Pharmacol 1991, 42:1849-1857.
14. Wang L., Wu B., Sun Y., Xu T., Zhang X., Zhou M., et al. Translocation of protein kinase C isoforms is involved in propofol-induced endothelial nitric oxide synthase activation. Br J Anaesth 2010, 104:606-612.
15. + channel blocker. Anesth Analg 1993, 76:24-32.
16. Yamanoue T., Brum J.M., Estafanous F.G. Vasodilation and mechanism of action of propofol in porcine coronary artery. Anesthesiology 1994, 81:443-451.
17. Smith I., White P.F., Nathanson M., Gouldson R. Propofol: an update on its clinical use. Anesthesiology 1994, 81:1005-1043.
18. Chen S.J., Li S.Y., Shih C.C., Liao M.H., Wu C.C. NO contributes to abnormal vascular calcium regulation and reactivity induced by peritonitis-associated septic shock in rats. Shock 2010, 33:473-478.
19. Bolton T.B. Mechanisms of action of transmitters and other substances on smooth muscle. Physiol Rev 1979, 59:606-718.
20. Karaki H., Ozaki H., Hori M., Mitsui-Saito M., Amano K., Harada K., et al. Calcium movements, distribution, and functions in smooth muscle. Pharmacol Rev 1997, 49:157-230.
21. Van Breemen C., Aaronson P., Loutzenhiser R. Sodium-calcium interactions in mammalian smooth muscle. Pharmacol Rev 1978, 30:167-208.
22. Grissom T.E., Bina S., Hart J., Muldoon S.M. Effect of halothane on phenylephrine-induced vascular smooth muscle contractions in endotoxin-exposed rat aortic rings. Crit Care Med 1996, 24:287-293.
23. Wu C.C., Chen S.J., Szabo C., Thiemermann C., Vane J.R. Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock. Br J Pharmacol 1995, 114:1666-1672.
24. +-ATPase in the aorta from rats with endotoxic shock. Shock 2005, 23:179-185.
25. Hoang L.M., Mathers D.A. Internally applied endotoxin and the activation of BK channels in cerebral artery smooth muscle via a nitric oxide-like pathway. Br J Pharmacol 1998, 123:5-12.
26. Sorrentino R. d'Emmanuele di Villa Bianca R, Lippolis L, Sorrentino L, Autore G, Pinto A. Involvement of ATP-sensitive potassium channels in a model of a delayed vascular hyporeactivity induced by lipopolysaccharide in rats. Br J Pharmacol 1999, 127:1447-1453.
27. Van Hove C.E., Van der Donckt C., Herman A.G., Bult H., Fransen P. Vasodilator efficacy of nitric oxide depends on mechanisms of intracellular calcium mobilization in mouse aortic smooth muscle cells. Br J Pharmacol 2009, 158:920-930.
28. Horibe M., Ogawa K., Sohn J.T., Murray P.A. Propofol attenuates acetylcholine-induced pulmonary vasorelaxation: role of nitric oxide and endothelium-derived hyperpolarizing factors. Anesthesiology 2000, 93:447-455.
29. Park K.W., Dai H.B., Lowenstein E., Sellke F.W. Propofol-associated dilation of rat distal coronary arteries is mediated by multiple substances, including endothelium-derived nitric oxide. Anesth Analg 1995, 81:1191-1196.
30. Nagakawa T., Yamazaki M., Hatakeyama N., Stekiel T.A. The mechanisms of propofol-mediated hyperpolarization of in situ rat mesenteric vascular smooth muscle. Anesth Analg 2003, 97:1639-1645.
31. Ca is involved in the relaxing effect of propofol on coronary arteries. Eur J Anaesthesiol 2004, 21:226-230.
32. Yamazaki M., Nagakawa T., Hatakeyama N., Shibuya N., Stekiel T.A. The effects of propofol on neural and endothelial control of in situ rat mesenteric vascular smooth muscle transmembrane potentials. Anesth Analg 2002, 94:892-897.
33. Cena J.J., Lalu M.M., Cho W.J., Chow A.K., Bagdan M.L., Daniel E.E., et al. Inhibition of matrix metalloproteinase activity in vivo protects against vascular hyporeactivity in endotoxemia. Am J Physiol Heart Circ Physiol 2010, 298:H45-H51.
34. Kirkpatrick T., Cockshott I.D., Douglas E.J., Nimmo W.S. Pharmacokinetics of propofol (Diprivan) in elderly patients. Br J Anaesth 1998, 60:146-150.
35. Servin F., Desmonts J.M., Haberer J.P., Cockshott I.D., Plummer G.F., Farinotti R. Pharmacokinetics and protein binding of propofol in patients with cirrhosis. Anesthesiology 1988, 69:887-891.