Evaluation of prognosis for carcinoma of unknown origin in elderly patients

Oncology (Switzerland)

Volumn 83, Issue 1, 2012, Pages 24-30

  Lu, Hsueh Ju ^a,b   Chen, Kuo Wei ^a,b   Tzeng, Cheng Hwai ^a,b   Liu, Jin Hwang ^a,b   Chiou, Tzeon Jye ^a,b   Yen, Chueh Chuan ^a,b   Chao, Ta Chung ^a,b   Teng, Hao Wei ^a,b   Chen, Ming Huang ^a,b   Liu, Chun Yu ^a,b   Wang, Wei Shu ^b   Chang, Peter Mu Hsin ^a,b   Yang, Muh Hwa ^a,b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Carcinoma of unknown origin; Elderly; Prognostic factor

Indexed keywords

ALBUMIN; LACTATE DEHYDROGENASE;

AGED; ALBUMIN BLOOD LEVEL; ARTICLE; BLOOD CELL COUNT; CANCER PROGNOSIS; CARCINOMA; CARCINOMA OF UNKNOWN ORIGIN; COMORBIDITY; ELDERLY CARE; FEMALE; GERIATRICS; HISTOPATHOLOGY; HUMAN; LACTATE DEHYDROGENASE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL;

AGED; AGED, 80 AND OVER; BLOOD CELL COUNT; CARCINOMA; COMORBIDITY; FEMALE; HUMANS; L-LACTATE DEHYDROGENASE; MALE; MULTIVARIATE ANALYSIS; NEOPLASM METASTASIS; NEOPLASMS, UNKNOWN PRIMARY; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; SERUM ALBUMIN; SURVIVAL RATE;

EID: 84862489120     PISSN: 00302414     EISSN: 14230232     Source Type: Journal    
DOI: 10.1159/000337983     Document Type: Article

References (29)

1. Hutchins LF, Unger JM, Crowley JJ, Coltman CA Jr, Albain KS: Underrepresentation of patients 65 years of age or older in cancertreatmenttrials. N Engl J Med 1999; 341: 2061-2067. (Pubitemid 30035956)
2. Smith BD, Smith GL, Hurria A, Hortobagyi GN, Buchholz TA: Future of cancer incidence in the United States: burdens upon an aging, changing nation. J Clin Oncol 2009; 27: 2758-2765.
3. Chiang CJ, Chen YC, Chen CJ, You SL, Lai MS: Cancer trends in Taiwan. Jpn J Clin Oncol 2010; 40: 897-904.
4. Yancik R, Ries LG: Cancer in the aged. An epidemiologic perspective on treatment issues. Cancer 1991; 68: 2502-2510.
5. Yancik R: Cancer burden in the aged: an epidemiologic and demographic overview. Cancer 1997; 80: 1273-1283. (Pubitemid 27407230)
6. Warren JL, Mariotto AB, Meekins A, Topor M, Brown ML: Current and future utilization of services from medical oncologists. J Clin Oncol 2008; 26: 3242-3247.
7. Leung KK, Tang LY, Chie WC, Lue BH, Lee LT: Mortality trends of elderly people in Taiwan from 1974 to 1994. Age Ageing 1999; 28:199-203.
8. Balducci L, Extermann M: Management of cancer in the older person: a practical approach. Oncologist 2000; 5: 224-237. (Pubitemid 30429942)
9. Pavlidis N, Briasoulis E, Hainsworth J, Greco FA: Diagnostic and therapeutic management of cancer of an unknown primary. Eur J Cancer 2003; 39: 1990-2005. (Pubitemid 37297755)
10. van de Wouw AJ, Janssen-Heijnen ML, Coebergh JW, Hillen HF: Epidemiology of unknown primary tumours; incidence and population-based survival of 1285 patients in Southeast Netherlands, 1984-1992. Eur J Cancer 2002; 38: 409-413. (Pubitemid 34121969)
11. Havlik RJ, Yancik R, Long S, Ries L, Edwards B: The National Institute on Aging and the National Cancer Institute SEER collaborative study on comorbidity and early diagnosis of cancer in the elderly. Cancer 1994; 74: 2101-2106. (Pubitemid 24304381)
12. Yancik R, Wesley MN, Ries LA, Havlik RJ, Long S, Edwards BK, Yates JW: Comorbidity and age as predictors of risk for early mortality of male and female colon carcinoma patients: a population-based study. Cancer 1998; 82: 2123-2134. (Pubitemid 28240818)
13. Abbruzzese JL, Abbruzzese MC, Hess KR, Raber MN, Lenzi R, Frost P: Unknown primary carcinoma: natural history and prognostic factors in 657 consecutive patients. J Clin Oncol 1994; 12: 1272-1280. (Pubitemid 24173944)
14. Chen YM, Lin KC, Tsai CM, Perng RP: Survival status of veterans with lung cancer is poorer than that among civilians due to age and sex differences: a study of Chinese veterans in Taiwan. J Chin Med Assoc 2008; 71: 286-293.
15. Huo TI, Huang YH, Hsia CY, Su CW, Lin HC, Hsu CY, Lee PC, Lui WY, Loong CC, Chiang JH, Chiou YY, Lee SD: Characteristics and outcome of patients with dual hepatitis B and C-associated hepatocellular carcinoma: are they different from patients with single virus infection? Liver Int 2009; 29: 767-773.
16. Balducci L: Management of cancer in the elderly. Oncology (Williston Park) 2006; 20: 135-143, discussion 144, 146, 151, 152. (Pubitemid 46931060)
17. Kodaira M, Takahashi S, Yamada S, Ueda K, Mishima Y, Takeuchi K, Yamamoto N, Ishikawa Y, Yokoyama M, Saotome T, Terui Y, Hatake K: Bone metastasis and poor performance status are prognostic factors for survival of carcinoma of unknown primary site in patients treated with systematic chemotherapy. Ann Oncol 2010; 21: 1163-1167.
18. Seve P, Sawyer M, Hanson J, Broussolle C, Dumontet C, Mackey JR: The influence of comorbidities, age, and performance status on the prognosis and treatment of patients with metastatic carcinomas of unknown primary site: a population-based study. Cancer 2006; 106: 2058-2066. (Pubitemid 43673223)
19. Seve P, Ray-Coquard I, Trillet-Lenoir V, Sawyer M, Hanson J, Broussolle C, Negrier S, Dumontet C, Mackey JR: Low serum albumin levels and liver metastasis are powerful prognostic markers for survival in patients with carcinomas of unknown primary site. Cancer 2006; 107: 2698-2705. (Pubitemid 44845626)
20. Hines RB, Chatla C, Bumpers HL, Waterbor JW, McGwin G Jr, Funkhouser E, Coffey CS, Posey J, Manne U: Predictive capacity of three comorbidity indices in estimating mortality after surgery for colon cancer. J Clin Oncol 2009; 27: 4339-4345.
21. Al-Shaiba R, McMillan DC, Angerson WJ, Leen E, McArdle CS, Horgan P: The relationship between hypoalbuminaemia, tumour volume and the systemic inflammatory response in patients with colorectal liver metastases. Br J Cancer 2004; 91: 205-207. (Pubitemid 39037059)
22. McMillan DC, Crozier JE, Canna K, Angerson WJ, McArdle CS: Evaluation of an inflammation-based prognostic score (GPS) in patients undergoing resection for colon and rectal cancer. Int J Colorectal Dis 2007; 22: 881-886. (Pubitemid 46952036)
23. Mabuchi S, Matsumoto Y, Isohashi F, Yoshioka Y, Ohashi H, Morii E, Hamasaki T, Aozasa K, Mutch DG, Kimura T: Pretreatment leukocytosis is an indicator of poor prognosis in patients with cervical cancer. Gynecol Oncol 2011; 122: 25-32.
24. Qiu MZ, Yuan ZY, Luo HY, Ruan DY, Wang ZQ, Wang FH, Li YH, Xu RH: Impact of pretreatment hematologic profile on survival of colorectal cancer patients. Tumor Biol 2010; 31: 255-260.
25. Kasuga I, Makino S, Kiyokawa H, Katoh H, Ebihara Y, Ohyashiki K: Tumor-related leukocytosis is linked with poor prognosis in patients with lung carcinoma. Cancer 2001; 92: 2399-2405. (Pubitemid 33029085)
26. Trivanovic D, Petkovic M, Stimac D: New prognostic index to predict survival in patients with cancer of unknown primary site with unfavourable prognosis. Clin Oncol (R Coll Radiol) 2009; 21: 43-48.
27. Culine S, Kramar A, Saghatchian M, Bugat R, Lesimple T, Lortholary A, Merrouche Y, Laplanche A, Fizazi K: Development and validation of a prognostic model to predict the length of survival in patients with carcinomas of an unknown primary site. J Clin Oncol 2002; 20: 4679-4683. (Pubitemid 36025285)
28. Vigano A, Bruera E, Jhangri GS, Newman SC, Fields AL, Suarez-Almazor ME: Clinical survival predictors in patients with advanced cancer. Arch Intern Med 2000; 160: 861-868. (Pubitemid 30165248)
29. Burns EA: Effects of aging on immune function. J Nutr Health Aging 2004; 8: 9-18. (Pubitemid 38200258)