Ultraviolet a induces endoplasmic reticulum stress response in human dermal fibroblasts

Cell Structure and Function

Volumn 37, Issue 1, 2012, Pages 49-53

  Yoshida, Hiderou ^a,c   Komori, Ryota ^a   Taniguchi, Mai ^a   Ichikawa, Yoshiaki ^b   Uemura, Aya ^c   Oku, Masaya ^c   Wakabayashi, Sadao ^a   Higuchi, Kazuhiko ^b  

^a UNIVERSITY OF HYOGO   (Japan)

^b KAO CORPORATION   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

ER stress ultraviolet A ATF6 XBP1 PERK

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ACTIVATING TRANSCRIPTION FACTOR 6ALPHA; INITIATION FACTOR 2; MESSENGER RNA; PROTEIN IRE1; PROTEIN PERK; REGULATOR PROTEIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; ATF6 PROTEIN, HUMAN; ERN2 PROTEIN, HUMAN; LUCIFERASE; MEMBRANE PROTEIN; PERK KINASE; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE;

ARTICLE; CELLULAR STRESS RESPONSE; ENDOPLASMIC RETICULUM STRESS; ENVIRONMENTAL STRESS; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; ULTRAVIOLET A RADIATION; CELL CULTURE; CYTOLOGY; DERMIS; ENDOPLASMIC RETICULUM; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PROTEIN FOLDING; RADIATION EXPOSURE; REPORTER GENE; ULTRAVIOLET RADIATION; UNFOLDED PROTEIN RESPONSE;

EUKARYOTA; MAMMALIA;

ACTIVATING TRANSCRIPTION FACTOR 6; CELLS, CULTURED; DERMIS; EIF-2 KINASE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; FIBROBLASTS; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; LUCIFERASES; MEMBRANE PROTEINS; PROTEIN FOLDING; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; ULTRAVIOLET RAYS; UNFOLDED PROTEIN RESPONSE;

EID: 84862332002     PISSN: 03867196     EISSN: 13473700     Source Type: Journal    
DOI: 10.1247/csf.11041     Document Type: Article

References (25)

1. Anand, S., Chakrabarti, E., Kawamura, H., Taylor, C.R., and Maytin, E.V. 2005. Ultraviolet light (UVB and UVA) induces the damage-responsive transcription factor CHOP/gadd153 in murine and human epidermis: evidence for a mechanism specific to intact skin. J. Invest. Dermatol., 125: 323-333.
2. Anderson, R.R. and Parrish, J.A. 1981. The optics of human skin. J. Invest. Dermatol., 77: 13-19.
3. Cullinan, S.B., Zhang, D., Hannink, M., Arvisais, E., Kaufman, R.J., and Diehl, J.A. 2003. Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol. Cell. Biol., 23: 7198-7209.
4. Gruber, F., Mayer, H., Lengauer, B., Mlitz, V., Sanders, J.M., Kadl, A., Bilban, M., de Martin, R., Wagner, O., Kensler, T.W., Yamamoto, M., Leitinger, N., and Tschachler, E. 2010. NF-E2-related factor 2 regulates the stress response to UVA-1-oxidized phospholipids in skin cells. FASEB J., 24: 39-48.
5. Kohno, K. 2010. Stress-sensing mechanisms in the unfolded protein response: similarities and differences between yeast and mammals. J. Biochem., 147: 27-33.
6. Lee, A.H., Chu, G.C., Iwakoshi, N.N., and Glimcher, L.H. 2005. XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands. EMBO J., 24: 4368-4380.
7. Malhotra, J.D. and Kaufman, R.J. 2007. Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword? Antioxid. Redox Signal., 9: 2277-2293.
8. Mera, K., Kawahara, K., Tada, K., Kawai, K., Hashiguchi, T., Maruyama, I. and Kanekura, T. 2010. ER signaling is activated to protect human HaCaT keratinocytes from ER stress induced by environmental doses of UVB. Biochem. Biophys. Res. Commun., 397: 350-354.
9. Mori, K. 2010. Divest yourself of a preconceived idea: transcription factor ATF6 is not a soluble protein! Mol. Biol. Cell, 21: 1435-1438.
10. Nadanaka, S., Okada, T., Yoshida, H., and Mori, K. 2007. Role of disulfide bridges formed in the luminal domain of ATF6 in sensing endoplasmic reticulum stress. Mol. Cell. Biol., 27: 1027-1043.
11. Oku, M., Tanakura, S., Uemura, A., Sohda, M., Misumi, Y., Taniguchi, M., Wakabayashi, S., and Yoshida, H. 2011. Novel cis-acting element GASE regulates transcriptional induction by the Golgi stress response. Cell Struct. Funct., 36: 1-12.
12. Reimold, A.M., Iwakoshi, N.N., Manis, J., Vallabhajosyula, P., Szomolanyi-Tsuda, E., Gravallese, E.M., Friend, D., Grusby, M.J., Alt, F., and Glimcher, L.H. 2001. Plasma cell differentiation requires the transcription factor XBP-1. Nature, 412: 300-307.
13. Ron, D. and Walter, P. 2007. Signal integration in the endoplasmic reticu-lum unfolded protein response. Nat. Rev. Mol. Cell Biol., 8: 519-529.
14. Sakurai, A., Nishimoto, M., Himeno, S., Imura, N., Tsujimoto, M., Kunimoto, M., and Hara, S. 2005. Transcriptional regulation of thiore-doxin reductase 1 expression by cadmium in vascular endothelial cells: role of NF-E2-related factor-2. J. Cell. Physiol., 203: 529-537.
15. Scheuner, D. and Kaufman, R.J. 2008. The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetes. Endocr. Rev., 29: 317-333.
16. Tyrrell, R.M. 2004. Solar ultraviolet A radiation: an oxidizing skin carcinogen that activates heme oxygenase-1. Antioxid. Redox Signal., 6: 835-840.
17. Uemura, A., Oku, M., Mori, K., and Yoshida, H. 2009. Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response. J. Cell Sci., 122: 2877-2886.
18. Wang, Y., Shen, J., Arenzana, N., Tirasophon, W., Kaufman, R.J., and Prywes, R. 2000. Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response. J. Biol. Chem., 275: 27013-27020.
19. Wu, S., Hu, Y., Wang, J.L., Chatterjee, M., Shi, Y., and Kaufman, R.J. 2002. Ultraviolet light inhibits translation through activation of the unfolded protein response kinase PERK in the lumen of the endoplasmic reticulum. J. Biol. Chem., 277: 18077-18083.
20. Yoshida, H., Haze, K., Yanagi, H., Yura, T., and Mori, K. 1998. Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors. J. Biol. Chem., 273: 33741-33749.
21. Yoshida, H., Okada, T., Haze, K., Yanagi, H., Yura, T., Negishi, M., and Mori, K. 2000. ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response. Mol. Cell. Biol., 20: 6755-6767.
22. Yoshida, H., Okada, T., Haze, K., Yanagi, H., Yura, T., Negishi, M., and Mori, K. 2001. Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response. Mol. Cell Biol., 21: 1239-1248.
23. Yoshida, H., Matsui, T., Hosokawa, N., Kaufman, R.J., Nagata, K., and Mori, K. 2003. A time-dependent phase shift in the mammalian unfolded protein response. Dev. Cell, 4: 265-271.
24. Yoshida, H. 2007. ER stress and diseases. FEBS J., 274: 630-658.
25. Zhang, K. 2010. Integration of ER stress, oxidative stress and the inflammatory response in health and disease. Int. J. Clin. Exp. Med., 3: 33-40.