A detailed re-assessment supports the conclusion of the Calabrese et al. (2011) paper that hormesis is commonly observed in the Ames assay

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 747, Issue 1, 2012, Pages 157-

  Calabrese, Edward J ^a   Stanek, Edward J ^a   Nascarella, Marc A ^b  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b GRADIENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMES TEST; HORMESIS; LETTER; MUTAGENICITY; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; STATISTICAL ANALYSIS; TOXICITY TESTING;

HORMESIS; MUTAGENICITY TESTS; MUTAGENS;

EID: 84862327730     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2012.04.008     Document Type: Letter

References (3)

1. Calabrese E.J., Stanek E.J., Nascarella M.A. Evidence for hormesis in mutagenicity dose-response relationships. Mutat. Res. 2011, 726:91-97.
2. Margolin B.H., Kaplan N., Zeiger E. Statistical analysis of Ames Salmonella/microsome test. Proc. Natl. Acad. Sci. U.S.A. 1981, 78:3779-3783.
3. Zieger E., Hoffmann G.R. An illusion of hormesis in the Ames test: statistical significance is not equivalent to biological significance. Mutat. Res. 2012.