A clinicopathological study of peripheral, small-sized high-grade neuroendocrine tumours of the lung: Differences between small-cell lung carcinoma and large-cell neuroendocrine carcinoma

European Journal of Cardio-thoracic Surgery

Volumn 41, Issue 4, 2012, Pages 841-846

  Isaka, Mitsuhiro ^a   Nakagawa, Kazuo ^a   Ohde, Yasuhisa ^a   Okumura, Takehiro ^a   Watanabe, Reiko ^a   Ito, Ichiro ^a   Nakajima, Takashi ^a   Kondo, Haruhiko ^a  

^a SHIZUOKA CANCER CENTER   (Japan)

Author keywords

High grade neuroendocrine tumour; Large cell neuroendocrine carcinoma; Prognosis; Small cell lung carcinoma; Small sized tumour; Stage IA

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; PROGASTRIN RELEASING PEPTIDE;

ADJUVANT CHEMOTHERAPY; ADULT; AGED; ARTICLE; CANCER RECURRENCE; CANCER SURVIVAL; CLINICAL ARTICLE; COMPARATIVE STUDY; FEMALE; HUMAN; LARGE CELL NEUROENDOCRINE CARCINOMA; LUNG SMALL CELL CANCER; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; TUMOR VOLUME; CANCER STAGING; CARCINOMA; LARGE CELL CARCINOMA; LUNG RESECTION; LUNG TUMOR; LYMPH NODE METASTASIS; METASTASIS; METHODOLOGY; MIDDLE AGED; PATHOLOGY; PROGNOSIS; SMALL CELL CARCINOMA; SURVIVAL; TREATMENT OUTCOME;

AGED; CARCINOMA, LARGE CELL; CARCINOMA, NEUROENDOCRINE; CARCINOMA, SMALL CELL; CHEMOTHERAPY, ADJUVANT; FEMALE; HUMANS; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM STAGING; PNEUMONECTOMY; PROGNOSIS; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 84862323231     PISSN: 10107940     EISSN: 1873734X     Source Type: Journal    
DOI: 10.1093/ejcts/ezr132     Document Type: Article

References (25)

1. Travis WD, Colby TV, Corrin B, Shimosato Y, Brambilla E. Histlogical Typing of Lung and Pleural Tumours. World Health Organization International Histological Classification of Tumours. Berlin: Springer, 1999.
2. Travis WD, Brambilla E, Muller-Hermelink HK, Harris CC. Pathology and Genetics of Tumors of the Lung, Pleura, Thymus and Heart. World Health Organization International Histological Classification of Tumours. Lyon: IARC Press, 2004.
3. Gustafsson BI, Kidd M, Chan A, Malfertheiner MV, Modlin IM. Bronchopulmonary neuroendocrine tumors. Cancer 2008;113:5-21.
4. Brock MV, Hooker CM, Syphard JE, Westra W, Xu L, Alberg AJ et al. Surgical resection of limited disease small cell lung cancer in the new era of platinum chemotherapy: its time has come. J Thorac Cardiovasc Surg 2005;129:64-72.
5. Tsuchiya R, Suzuki K, Ichinose Y, Watanabe Y, Yasumitsu T, Ishizuka N et al. Phase II trial of postoperative adjuvant cisplatin and etoposide in patients with completely resected stage I-IIIa small cell lung cancer: the Japan Clinical Oncology Lung Cancer Study Group Trial ( JCOG9101). J Thorac Cardiovasc Surg 2005;129:977-83.
6. Takei H, Asamura H, Maeshima A, Suzuki K, Kondo H, Niki T et al. Large cell neuroendocrine carcinoma of the lung: a clinicopathologic study of eighty-seven cases. J Thorac Cardiovasc Surg 2002;124:285-92.
7. Iyoda A, Hiroshima K, Moriya Y, Sekine Y, Shibuya K, Iizasa T et al. Prognostic impact of large cell neuroendocrine histology in patients with pathologic stage Ia pulmonary non-small cell carcinoma. J Thorac Cardiovasc Surg 2006;132:312-5.
8. Iyoda A, Hiroshima K, Moriya Y, Takiguchi Y, Sekine Y, Shibuya K et al. Prospective study of adjuvant chemotherapy for pulmonary large cell neuroendocrine carcinoma. Ann Thorac Surg 2006;82:1802-7.
9. Rossi G, Cavazza A, Marchioni A, Longo L, Migaldi M, Sartori G et al. Role of chemotherapy and the receptor tyrosine kinases KIT, PDGFRalpha, PDGFRbeta, and Met in large-cell neuroendocrine carcinoma of the lung. J Clin Oncol 2005;23:8774-85.
10. Jones MH, Virtanen C, Honjoh D, Miyoshi T, Satoh Y, Okumura S et al. Two prognostically significant subtypes of high-grade lung neuroendocrine tumours independent of small-cell and large-cell neuroendocrine carcinomas identified by gene expression profiles. Lancet 2004;363: 775-81.
11. Hiroshima K, Iyoda A, Shida T, Shibuya K, Iizasa T, Kishi H et al. Distinction of pulmonary large cell neuroendocrine carcinoma from small cell lung carcinoma: a morphological, immunohistochemical, and molecular analysis. Mod Pathol 2006;19:1358-68.
12. Nitadori J, Ishii G, Tsuta K, Yokose T, Murata Y, Kodama T et al. Immunohistochemical differential diagnosis between large cell neuroendocrine carcinoma and small cell carcinoma by tissue microarray analysis with a large antibody panel. Am J Clin Pathol 2006;125: 682-92.
13. Goldstraw P, Crowley J, Chansky K, Giroux DJ, Groome PA, Rami-Porta R et al. The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours. J Thorac Oncol 2007;2:706-14.
14. Shepherd FA, Crowley J, Van Houtte P, Postmus PE, Carney D, Chansky K et al. The International Association for the Study of Lung Cancer lung cancer staging project: proposals regarding the clinical staging of small cell lung cancer in the forthcoming (seventh) edition of the tumor, node, metastasis classification for lung cancer. J Thorac Oncol 2007;2: 1067-77.
15. Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y et al. International Association for the Study of Lung Cancer/ American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma. J Thorac Oncol 2011;6:244-85.
16. Quoix E, Fraser R, Wolkove N, Finkelstein H, Kreisman H. Small cell lung cancer presenting as a solitary pulmonary nodule. Cancer 1990;66:577-82.
17. Asamura H, Kameya T, Matsuno Y, Noguchi M, Tada H, Ishikawa Y et al. Neuroendocrine neoplasms of the lung: a prognostic spectrum. J Clin Oncol 2006;24:70-6.
18. Wojcik E, Kulpa JK, Sas-Korczynska B, Korzeniowski S, Jakubowicz J. ProGRP and NSE in therapy monitoring in patients with small cell lung cancer. Anticancer Res 2008;28:3027-33.
19. Inoue M, Miyoshi S, Yasumitsu T, Mori T, Iuchi K, Maeda H et al. Surgical results for small cell lung cancer based on the new TNM staging system. Thoracic Surgery Study Group of Osaka University, Osaka, Japan. Ann Thorac Surg 2000;70:1615-9.
20. de Antonio DG, Alfageme F, Gamez P, Cordoba M, Varela A. Results of surgery in small cell carcinoma of the lung. Lung Cancer 2006;52:299-304.
21. den Bakker MA, Willemsen S, Grunberg K, Noorduijn LA, van Oosterhout MF van Suylen RJ et al. Small cell carcinoma of the lung and large cell neuroendocrine carcinoma interobserver variability. Histopathology 2010;56:356-63.
22. Igawa S, Watanabe R, Ito I, Murakami H, Takahashi T, Nakamura Y et al. Comparison of chemotherapy for unresectable pulmonary high-grade non-small cell neuroendocrine carcinoma and small-cell lung cancer. Lung Cancer 2010;68:438-45.
23. Battafarano RJ, Fernandez FG, Ritter J, Meyers BF, Guthrie TJ, Cooper JD et al. Large cell neuroendocrine carcinoma: an aggressive form of nonsmall cell lung cancer. J Thorac Cardiovasc Surg 2005;130:166-72.
24. Mountain CF. Revisions in the International System for Staging Lung Cancer. Chest 1997;111:1710-17.
25. Rami-Porta R, Ball D, Crowley J, Giroux DJ, Jett J, Travis WD et al. The IASLC Lung Cancer Staging Project: proposals for the revision of the T descriptors in the forthcoming (seventh) edition of the TNM classification for lung cancer. J Thorac Oncol 2007;2:593-602.