Construction of paclitaxel-loaded poly (2-hydroxyethyl methacrylate)-g-poly (lactide)- 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine copolymer nanoparticle delivery system and evaluation of its anticancer activity

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 1313-1328

  Ma, Xiaowei ^a,b   Wang, Huan ^a,b   Jin, Shubin ^a,b   Wu, Yan ^a,b   Liang, Xing Jie ^a,b  

^a NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

1,2 dipalmitoyl sn glycero 3 phosphoethanolamine; Antitumor activity; Biocompatibility; Controlled release; Nanoparticles; Poly (2 hydroxyethyl methacrylate)

Indexed keywords

NANOPARTICLE; PACLITAXEL; POLY(2 HYDROXYETHYL METHACRYLATE) G POLY(LASCTIDE) 1,2 DIPALMITOYL SN GLYCERO 3 PHOSPHOETHANOLAMINE COPOLYMER NANOPARTICLE; UNCLASSIFIED DRUG; 1,2-DIPALMITOYL-3-PHOSPHATIDYLETHANOLAMINE; 2 HYDROXYETHYL METHACRYLATE; ANTINEOPLASTIC AGENT; DIPALMITOYLPHOSPHATIDYLETHANOLAMINE; DRUG CARRIER; METHACRYLIC ACID DERIVATIVE; PHOSPHATIDYLETHANOLAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CANCER REGRESSION; CELL STRAIN MCF 7; CONCENTRATION RESPONSE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG FORMULATION; DRUG LOADING CONTENT; DRUG SCREENING; DRUG TARGETING; FEMALE; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; MOUSE; NANOENCAPSULATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; PH; PHARMACEUTICS; SYNTHESIS; THERMOGRAVIMETRY; THERMOSTABILITY; TUMOR XENOGRAFT; ANIMAL; BREAST TUMOR; CELL PROLIFERATION; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG EFFECT; METABOLISM; NUDE MOUSE; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; METHACRYLATES; MICE; MICE, NUDE; NANOPARTICLES; PACLITAXEL; PHOSPHATIDYLETHANOLAMINES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84862316936     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S29371     Document Type: Article

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