Genomics and Proteomics in Reverse Vaccines

Microbial Proteomics: Functional Biology of Whole Organisms

Volumn , Issue , 2005, Pages 379-393

  Grandi, Guido ^a  

^a CHIRON VACCINES   (Italy)

Author keywords

Additional gene selection criteria in reverse vaccinology; Genomics and proteomics in reverse vaccines; Reverse vaccinology with transcriptomic and proteomic analysis

Indexed keywords

EID: 84862311826     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/0471973165.ch20     Document Type: Chapter

References (35)

1. Grandi, G., Antibacterial vaccine design using genomics and proteomics, Trends Biotechnol. 2001, 19, 181-188.
2. Hoffman, S. L., Subramanian, G. M., Collins, F. H., and Venter, J. C., Plasmodium, human and Anopheles genomics and malaria, Nature 2002, 415, 702-709.
3. Pizza, M., Scarlato, V., Masignani, V., Giuliani, M. M., Aricò, B., Comanducci, M., Jennings, G. T., Baldi, L., Bartolini, E., Capecchi, B., Galeotti, C. L., Luzzi, E., Manetti, R., Marchetti, E., Mora, M., Nuti, S., Ratti, G., Santini, L., Savino, S., Scarselli, M., Storni, E., Zuo, P., Broecker, M., Hundt, E., Knapp, B., Blair, E., Mason, T., Tettelin, H., Hood, D. W., Jeffries, A. C., Saunders, N. J., Granoff, D. M., Venter, J. C., Moxon, E. R., Grandi, G., and Rappuoli, R., Identification of vaccine candidates against serogroup B meningococcus genome sequencing, Science 2000, 287, 1816-1820.
4. Rappuoli, R., Reverse vaccinology, Curr. Opin. Microbiol. 2000, 3, 445-450.
5. Grandi, G., Bioinformatics, DNA microarrays and proteomics in baccine discovery: Competing or complementary technologies?, in G. Grandi (Ed.), Genomics, Proteomics and Vaccines, Wiley, New York, 2004.
6. Gotschlich, E. C., Liu, T. Y., and Artenstein, M. S., Human immunity to the Meningococcus. 3. Preparation and immunochemical properties of the group A, group B and group C meningococcal polysaccharides, J. Exp. Med. 1969, 129, 1349-1365.
7. Gotschlich, E. C., Goldschneider, I., and Artenstein, M. S., Human immunity to the meningococcus. IV. Immunogenicity of group A and group C meningococcal polysaccharides in human volunteers, J. Exp. Med 1969, 129, 1367-1384.
8. Scholten, R. J., Bijlmer, H. A., Poolman, J. T., Kuipers, B., Caugant, D. A., Van Alphen, L., Dankert, J., and Valkenburg, H. A., Meningococcal disease in The Netherlands, 1958-1990: A steady increase in the incidence since 1982 partially caused by new serotypes and subtypes of Neisseria meningitidis. Clin. Infect. Dis. 1993, 16, 237-246.
9. Hayrinen, J., Jennings, H., Raff, H. V., Rougon, G., Hanai, N., Gerardy-Schahn, R., and Finne, J., Antibodies to polysialic acid and its N-propyl derivative: Binding properties and interaction with human embryonal brain glycopeptides, J. Infect. Dis. 1995, 171, 1481-1490.
10. Finne, J., Bitter-Suermann, D., Goridis, C., and Finne, U., AnIgG monoclonal antibody to group B meningococci cross-reacts with developmentally regulated polysialic acid units of glycoproteins in neural and extraneural tissues, J. Immunol. 1987, 138, 4402-4407.
11. Poolman, J. T., Development of a meningococcal vaccine, Infect. Agents Dis. 1995, 4, 13-28.
12. Martin, D., Cadieux, N., Hamel, J., and Brodeur, B. R., Highly conserved Neisseria meningitidis surface protein confers protection against experimental infection, J. Exp. Med. 1997, 185, 1173-1183.
13. Tettelin, H., Saunders, N. J., Nelson, K. E., Jeffries, A. C., Heidelberg, J., Eisen, J. A., Ketchum, K. A., Hood, D. W., Dodson, R. J., Nelson, W. C., Gwinn, M. L., DeBoy, R., Peterson, J. D., Hickey, E. K., Haft, D. H., Salzberg, S. L., White, O., Fleischmann, R. D., Dougherty, B. A., Mason, T., Ciecko, A., Parksey, D. S., Blair, E., Cittone, H., Clark, E. B., Cotton, M. D., Utterback, T. R., Khouri, H., Qin, H., Vamathevan, J., Gill, J., Scarlato, V., Masignani, V., Pizza, M., Grandi, G., Sun, L., Smith, H. O., Fraser, C. M., Moxon, E. R., Rappuoli, R., and Venter, J. C., Complete genome sequence of Neisseria meningitidis serotype B strain MC58. Science 2000, 287, 1809-1815.
14. Goldscheider, I., Gotschlich, E. C., and Artenstein, M.S., Human immunity to meningococcus. I. The role of humoral antibodies. J. Exp. Med. 1969, 129, 1307-1326.
15. Schuchat, A., Epidemiology of group B streptococcal disease in the United States: Shifting paradigms, Clin. Microbiol. Rev. 1998, 11, 497-513.
16. Paoletti, L. C., Wessels, M. R., Rodewald, A. K., Shroff, A. A., Jennings, H. J., and Kasper, D. L., Neonatal mouse protection against infection with multiple group B streptococcal (GBS) serotypes by maternal immunization with a tetravalent GBS polysaccharide-tetanus toxoid conjugate vaccine, Infect. Immun. 1994, 62, 3236-3243.
17. Berg, S., Trollfors, B., Lagergard, T., Zackrisson, G., and Claesson, B. A., Serotypes and clinical manifestations of group B streptococcal infections in western Sweden, Clin. Microbiol. Infect. 2000, 6, 9-13.
18. Davies, H. D., Raj, S., Adair, C., Robinson, J., and McGeer, A., Population-based active surveillance for neonatal group B streptococcal infections in Alberta, Canada: Implications for vaccine formulation, Pediatr. Infect. Dis. J. 2001, 20, 879-884.
19. Hickman, M. E., Rench, M. A., Ferrieri, P., and Baker, C. J., Changing epidemiology of group B streptococcal colonization, Pediatrics 1999, 104, 203-209.
20. Lin, F. Y., Clemens, J. D., Azimi, P. H., Regan, J. A., Weisman, L. E., Philips, J. B. 3rd, Rhoads, G. G., Clark, P., Brenner, R. A., and Ferrieri, P., Capsular polysaccharide types of group B streptococcal isolates from neonates with early-onset systemic infection. J. Infect. Dis., 1998, 177, 790-792.
21. Suara, R. O., Adegbola, R. A., Mulholland, E. K., Greenwood, B. M., and Baker, C. J., Seroprevalence of antibodies to group B streptococcal polysaccharides in Gambian mothers and their newborns, J. Natl. Med. Assoc. 1998, 90, 109-114.
22. Tettelin, H., Masignani, V., Cieslewicz, M. J., Eisen, J. A., Peterson, S., Wessels, M. R., Paulsen, I. T., Nelson, K. E., Margarit, I., Read, T. D., Madoff, L. C., Wolf, A. M., Beanan, M. J., Brinkac, L. M., Daugherty, S. C., DeBoy, R. T., Durkin, A. S., Kolonay, J. F., Madupu, R., Lewis, M. R., Radune, D., Fedorova, N. B., Scanlan, D., Khouri, H., Mulligan, S., Carty, H. A., Cline, R. T., Van Aken, S. E., Gill, J., Scarselli, M., Mora, M., Iacobini, E. T., Brettoni, C., Galli, G., Mariani, M., Vegni, F., Maione, D., Rinaudo, D., Rappuoli, R., Telford, J. L., Kasper, D. L., Grandi, G., and Fraser, C.M., Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae, Proc. Natl. Acad. Sci. USA 2002, 99, 12391-12396.
23. Cunningham, M. W., Pathogenesis of group A streptococcal infections, Clin. Microbiol. Rev. 2000, 13, 470-511.
24. Dale, J. B., Group A streptococcal vaccines, Infect. Dis. Clin. North. Am. 1999, 13, 227-243, viii.
25. Hu, M. C., Walls, M. A., Stroop, S. D., Reddish, M. A., Beall, B., and Dale, J.B., Immunogenicity of a 26-valent group A streptococcal vaccine, Infect. Immun. 2002, 70, 2171-2177.
26. Baltimore, R. S., Kasper, D. L., Baker, C. J., and Goroff, D. K., Antigenic specificity of opsonophagocytic antibodies in rabbit anti-sera to group B streptococci, J. Immunol. 1977, 118, 673-678.
27. Stephers, R. S. (Ed.), Chlamydia. Intracellular Biology, Pathogenesis, and Immunity, ASM Press, Washington, DC, 1999.
28. Ho, J.L., He, S., Hu, A., Geng, J., Basile, F.G., Almeida, M.G., Saito, A. Y., Laurence, J., and Johnson, W. D. Jr., Neutrophils from human immunodeficiency virus (HIV)-seronegative donors induce HIV replication from HIV-infected patients' mononuclear cells and cell lines: An in vitro model of HIV transmission facilitated by Chlamydia trachomatis, J. Exp. Med. 1995, 181, 1493-1505.
29. Ramsey, K. H., Cotter, T. W., Salyer, R. D., Miranpuri, G. S., Yanez, M. A., Poulsen, C. E., DeWolfe, J. L., and Byrne, G. I., Prior genital tract infection with a murine or human biovar of Chlamydia trachomatis protects mice against heterotypic challenge infection, Infect. Immun. 1999, 67, 3019-3025.
30. Bonci et al., submitted for publication.
31. Montigiani, S., Falugi, F., Scarselli, M., Finco, O., Petracca, R., Galli, G., Mariani, M., Manetti, R., Agnusdei, M., Cevenini, R., Donati, M., Nogarotto, R., Norais, N., Garaguso, I., Nuti, S., Saletti, G., Rosa, D., Ratti, G., and Grandi, G., Genomic approach for analysis of surface proteins in Chlamydia pneumoniae, Infect. Immun. 2002, 70, 368-379.
32. Finco et al., Vaccine, in press.
33. Grifantini, R., Bartolini, E., Muzzi, A., Draghi, M., Frigimelica, E., Berger, J., Ratti, G., Petracca, R., Galli, G., Agnusdei, M., Giuliani, M. M., Santini, L., Brunelli, B., Tettelin, H., Rappuoli, R., Randazzo, F., and Grandi, G., Previously unrecognized vaccine candidates against group B meningococcus identified by DNA microarrays, Nat. Biotechnol. 2002, 20, 914-921.
34. Molloy, M. P., Herbert, B. R., Slade, M. B., Rabilloud, T., Nouwens, A. S., Williams, K. L., and Gooley, A. A., Proteomic analysis of the Escherichia coli outer membrane, Eur. J. Biochem. 2000, 267, 2871-2881.
35. Lei, B., Liu, M., Chesney, G. L., and Musser, J. M., Identification of new candidate vaccine antigens made by Streptococcus pyogenes: Purification and characterization of 16 putative extracellular lipoproteins, J. Infect. Dis. 2004, 189, 79-89.