The clinical utility of chromosomal microarray in childhood neurological disorders

Developmental Medicine and Child Neurology

Volumn 54, Issue 7, 2012, Pages 582-583

  Kurian, Manju A ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AUTISM; CHILDHOOD DISEASE; CHROMOSOMAL MICROARRAY; COPY NUMBER VARIATION; DNA MICROARRAY; EPILEPSY; GENE DELETION; HUMAN; INTELLECTUAL IMPAIRMENT; MOTOR DYSFUNCTION; NEUROIMAGING; NEUROLOGIC DISEASE; NOTE; PATHOGENESIS; PRIORITY JOURNAL;

CHROMOSOME DELETION; FEMALE; GENE DELETION; HUMANS; MALE; MOVEMENT DISORDERS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS;

EID: 84862310330     PISSN: 00121622     EISSN: 14698749     Source Type: Journal    
DOI: 10.1111/j.1469-8749.2012.04304.x     Document Type: Note

References (7)

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3. Mefford HC, Yendle SC, Hsu C, et al. Rare copy number variants are an important cause of epileptic encephalopathies. Ann Neurol 2011; 70: 974-85.
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5. Hochstenbach R, Buizer-Voskamp JE, Vorstman JA, Ophoff RA. Genome arrays for the detection of copy number variations in idiopathic mental retardation, idiopathic generalized epilepsy and neuropsychiatric disorders: lessons for diagnostic workflow and research. Cytogenet Genome Res 2011; 135: 174-202.
6. Dale RC, Grattan-Smith P, Nicholson M, Peters GB. Microdeletions detected using chromosomal microarray in children with suspected genetic movement disorders: a single-centre study. Dev Med Child Neurol 2012; 54: 618-3.
7. Kurian MA, Meyer E, Vassallo G, et al. Phospholipase C beta 1 deficiency is associated with early-onset epileptic encephalopathy. Brain 2010; 133: 2964-70.