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Volumn 2012, Issue , 2012, Pages

Cell and molecular biology underpinning the effects of PEDF on cancers in general and osteosarcoma in particular

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOSTATIN; CHECKPOINT KINASE 1; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HYPOXIA INDUCIBLE FACTOR 1; MATRIGEL; MATRIX METALLOPROTEINASE; PIGMENT EPITHELIUM DERIVED FACTOR; THROMBOSPONDIN 1; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; EYE PROTEIN; NERVE GROWTH FACTOR; PIGMENT EPITHELIUM-DERIVED FACTOR; SERINE PROTEINASE INHIBITOR;

EID: 84862299043     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2012/740295     Document Type: Review
Times cited : (23)

References (62)
  • 1
    • 84862271512 scopus 로고    scopus 로고
    • Cancer Society A. 2010
    • Cancer Society American,. 2010, http://www.cancer.org/Research/ CancerFactsFigures/CancerFactsFigures/index
  • 2
    • 33748312291 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor: A multimodal tumor inhibitor
    • DOI 10.1158/1535-7163.MCT-06-0107
    • Ek E. T. H., Dass C. R., Choong P. F. M., Pigment epithelium-derived factor: a multimodal tumor inhibitor Molecular Cancer Therapeutics 2006 5 7 1641 1646 (Pubitemid 44323231)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.7 , pp. 1641-1646
    • Ek, E.T.H.1    Dass, C.R.2    Choong, P.F.M.3
  • 3
    • 33749158265 scopus 로고    scopus 로고
    • PEDF: A potential molecular therapeutic target with multiple anti-cancer activities
    • DOI 10.1016/j.molmed.2006.08.009, PII S1471491406001961
    • Ek E. T. H., Dass C. R., Choong P. F. M., PEDF: a potential molecular therapeutic target with multiple anti-cancer activities Trends in Molecular Medicine 2006 12 10 497 502 (Pubitemid 44468197)
    • (2006) Trends in Molecular Medicine , vol.12 , Issue.10 , pp. 497-502
    • Ek, E.T.H.1    Dass, C.R.2    Choong, P.F.M.3
  • 4
    • 77954411013 scopus 로고    scopus 로고
    • PEDF as a treatment for cervical cancer
    • Murray A. R., Ma J. X., PEDF as a treatment for cervical cancer Cancer Biology and Therapy 2010 9 12 975 977
    • (2010) Cancer Biology and Therapy , vol.9 , Issue.12 , pp. 975-977
    • Murray, A.R.1    Ma, J.X.2
  • 5
    • 75349111879 scopus 로고    scopus 로고
    • In vitro and in vivo biological activity of PEDF against a range of tumors
    • Broadhead M. L., Dass C. R., Choong P. F., In vitro and in vivo biological activity of PEDF against a range of tumors Expert Opinion on Therapeutic Targets 2009 13 12 1429 1438
    • (2009) Expert Opinion on Therapeutic Targets , vol.13 , Issue.12 , pp. 1429-1438
    • Broadhead, M.L.1    Dass, C.R.2    Choong, P.F.3
  • 6
    • 77953253715 scopus 로고    scopus 로고
    • Antipermeability function of PEDF involves blockade of the MAP kinase/GSK/ -catenin signaling pathway and uPAR expression
    • Yang J., Duh E. J., Caldwell R. B., Ali Behzadian M., Antipermeability function of PEDF involves blockade of the MAP kinase/GSK/ -catenin signaling pathway and uPAR expression Investigative Ophthalmology and Visual Science 2010 51 6 3273 3280
    • (2010) Investigative Ophthalmology and Visual Science , vol.51 , Issue.6 , pp. 3273-3280
    • Yang, J.1    Duh, E.J.2    Caldwell, R.B.3    Ali Behzadian, M.4
  • 7
    • 4143122398 scopus 로고    scopus 로고
    • Decreased pigment epithelium-derived factor is associated with metastatic phenotype in human and rat prostate tumors
    • DOI 10.1158/0008-5472.CAN-04-0835
    • Halin S., Wikstrm P., Rudolfsson S. H., Stattin P., Doll J. A., Crawford S. E., Bergh A., Decreased pigment epithelium-derived factor is associated with metastatic phenotype in human and rat prostate tumors Cancer Research 2004 64 16 5664 5671 (Pubitemid 39095563)
    • (2004) Cancer Research , vol.64 , Issue.16 , pp. 5664-5671
    • Halin, S.1    Wikstrom, P.2    Rudolfsson, S.H.3    Stattin, P.4    Doll, J.A.5    Crawford, S.E.6    Bergh, A.7
  • 9
    • 3042700788 scopus 로고    scopus 로고
    • Antiangiogenic property of pigment epithelium-derived factor in hepatocellular carcinoma
    • DOI 10.1002/hep.20259
    • Matsumoto K., Ishikawa H., Nishimura D., Hamasaki K., Nakao K., Eguchi K., Antiangiogenic property of pigment epithelium-derived factor in hepatocellular carcinoma Hepatology 2004 40 1 252 259 (Pubitemid 38868944)
    • (2004) Hepatology , vol.40 , Issue.1 , pp. 252-259
    • Matsumoto, K.1    Ishikawa, H.2    Nishimura, D.3    Hamasaki, K.4    Nakao, K.5    Eguchi, K.6
  • 10
    • 0037371954 scopus 로고    scopus 로고
    • Wilms' tumor growth is suppressed by antiangiogenic pigment epithelium-derived factor in a xenograft model
    • DOI 10.1053/jpsu.2003.50104
    • Abramson L. P., Stellmach V., Doll J. A., Cornwell M., Arensman R. M., Crawford S. E., Ford H., Wilms' tumor growth is suppressed by antiangiogenic pigment epithelium-derived factor in a xenograft model Journal of Pediatric Surgery 2003 38 3 336 342 (Pubitemid 36278689)
    • (2003) Journal of Pediatric Surgery , vol.38 , Issue.3 , pp. 336-342
    • Abramson, L.P.1    Stellmach, V.2    Doll, J.A.3    Cornwell, M.4    Arensman, R.M.5    Crawford, S.E.6    Ford, H.7
  • 11
    • 0030569057 scopus 로고    scopus 로고
    • Organization, evolutionary conservation, expression and unusual Alu density of the human gene for pigment epithelium-derived factor, a unique neurotrophic serpin
    • Tombran-Tink J., Mazuruk K., Rodriguez I. R., Chung D., Linker T., Englander E., Chader G. J., Organization, evolutionary conservation, expression and unusual Alu density of the human gene for pigment epithelium-derived factor, a unique neurotrophic serpin. Molecular Vision 1996 2 11
    • (1996) Molecular Vision , vol.2 , pp. 11
    • Tombran-Tink, J.1    Mazuruk, K.2    Rodriguez, I.R.3    Chung, D.4    Linker, T.5    Englander, E.6    Chader, G.J.7
  • 12
    • 31644442359 scopus 로고    scopus 로고
    • Focus on molecules: Pigment epithelium-derived factor (PEDF)
    • DOI 10.1016/j.exer.2005.10.016, PII S0014483505003489
    • Patricia Becerra S., Focus on molecules: pigment epithelium-derived factor (PEDF) Experimental Eye Research 2006 82 5 739 740 (Pubitemid 43170874)
    • (2006) Experimental Eye Research , vol.82 , Issue.5 , pp. 739-740
    • Patricia Becerra, S.1
  • 13
    • 0037465705 scopus 로고    scopus 로고
    • Dual-site recognition of different extracellular matrix components by anti-angiogenic/neurotrophic serpin, PEDF
    • DOI 10.1021/bi0206558
    • Yasui N., Mori T., Morito D., Matsushita O., Kourai H., Nagata K., Koide T., Dual-site recognition of different extracellular matrix components by anti-angiogenic/neurotrophic serpin, PEDF Biochemistry 2003 42 11 3160 3167 (Pubitemid 36348624)
    • (2003) Biochemistry , vol.42 , Issue.11 , pp. 3160-3167
    • Yasui, N.1    Mori, T.2    Morito, D.3    Matsushita, O.4    Kourai, H.5    Nagata, K.6    Koide, T.7
  • 14
    • 0036104828 scopus 로고    scopus 로고
    • Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor
    • DOI 10.1038/nm0402-349
    • Volpert O. V., Zaichuk T., Zhou W., Reiher F., Ferguson T. A., Stuart P. M., Amin M., Bouck N. P., Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor Nature Medicine 2002 8 4 349 357 (Pubitemid 34407029)
    • (2002) Nature Medicine , vol.8 , Issue.4 , pp. 349-357
    • Volpert, O.V.1    Zaichuk, T.2    Zhou, W.3    Reiher, F.4    Ferguson, T.A.5    Stuart, P.M.6    Amin, M.7    Bouck, N.P.8
  • 15
  • 16
    • 36649003694 scopus 로고    scopus 로고
    • PEDF induces p53-mediated apoptosis through PPAR gamma signaling in human umbilical vein endothelial cells
    • Ho T. C., Chen S. L., Yang Y. C., Liao C. L., Cheng H. C., Tsao Y. P., PEDF induces p53-mediated apoptosis through PPAR gamma signaling in human umbilical vein endothelial cells Cardiovascular Research 2007 76 2 213 223
    • (2007) Cardiovascular Research , vol.76 , Issue.2 , pp. 213-223
    • Ho, T.C.1    Chen, S.L.2    Yang, Y.C.3    Liao, C.L.4    Cheng, H.C.5    Tsao, Y.P.6
  • 17
    • 35148822263 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor inhibits glioma cell growth in vitro and in vivo
    • DOI 10.1016/j.lfs.2007.08.025, PII S002432050700608X
    • Zhang T., Guan M., Xu C., Chen Y., Lu Y., Pigment epithelium-derived factor inhibits glioma cell growth in vitro and in vivo Life Sciences 2007 81 16 1256 1263 (Pubitemid 47539504)
    • (2007) Life Sciences , vol.81 , Issue.16 , pp. 1256-1263
    • Zhang, T.1    Guan, M.2    Xu, C.3    Chen, Y.4    Lu, Y.5
  • 18
    • 0033538517 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor: A potent inhibitor of angiogenesis
    • DOI 10.1126/science.285.5425.245
    • Dawson D. W., Volpert O. V., Gillis P., Crawford S. E., Xu H. J., Benedict W., Bouck N. P., Pigment epithelium-derived factor: a potent inhibitor of angiogenesis Science 1999 285 5425 245 248 (Pubitemid 29329995)
    • (1999) Science , vol.285 , Issue.5425 , pp. 245-248
    • Dawson, D.W.1    Volpert, O.V.2    Gillis, P.3    Crawford, S.E.4    Xu, H.-J.5    Benedict, W.6    Bouck, N.P.7
  • 19
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • DOI 10.1016/S0092-8674(00)80108-7
    • Hanahan D., Folkman J., Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis Cell 1996 86 3 353 364 (Pubitemid 26272076)
    • (1996) Cell , vol.86 , Issue.3 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 20
    • 11244297196 scopus 로고    scopus 로고
    • Extracellular phosphorylation converts pigment epithelium-derived factor from a neurotrophic to an antiangiogenic factor
    • DOI 10.1182/blood-2004-04-1569
    • Maik-Rachline G., Shaltiel S., Seger R., Extracellular phosphorylation converts pigment epithelium-derived factor from a neurotrophic to an antiangiogenic factor Blood 2005 105 2 670 678 (Pubitemid 40070751)
    • (2005) Blood , vol.105 , Issue.2 , pp. 670-678
    • Maik-Rachline, G.1    Shaltiel, S.2    Seger, R.3
  • 23
    • 41749104248 scopus 로고    scopus 로고
    • Tumor suppressor FUS1 signaling pathway
    • DOI 10.1097/JTO.0b013e31816bce65, PII 0124389420080400000002
    • Ji L., Roth J. A., Tumor suppressor FUS1 signaling pathway Journal of Thoracic Oncology 2008 3 4 327 330 (Pubitemid 351489470)
    • (2008) Journal of Thoracic Oncology , vol.3 , Issue.4 , pp. 327-330
    • Ji, L.1    Roth, J.A.2
  • 24
    • 38749114995 scopus 로고    scopus 로고
    • Oncogenes and cancer
    • DOI 10.1056/NEJMra072367
    • Croce C. M., Oncogenes and cancer New England Journal of Medicine 2008 358 5 502 511 (Pubitemid 351185806)
    • (2008) New England Journal of Medicine , vol.358 , Issue.5 , pp. 502-511
    • Croce, C.M.1
  • 26
    • 33845318548 scopus 로고    scopus 로고
    • What determines blood vessel structure? Genetic prespecification vs. hemodynamics
    • DOI 10.1152/physiol.00020.2006
    • Jones E. A. V., Le Noble F., Eichmann A., What determines blood vessel structure? Genetic prespecification vs. hemodynamics Physiology 2006 21 6 388 395 (Pubitemid 44879247)
    • (2006) Physiology , vol.21 , Issue.6 , pp. 388-395
    • Jones, E.A.V.1    Le Noble, F.2    Eichmann, A.3
  • 29
    • 0038376002 scopus 로고    scopus 로고
    • Molecular regulation of vessel maturation
    • DOI 10.1038/nm0603-685
    • Jain R. K., Molecular regulation of vessel maturation Nature Medicine 2003 9 6 685 693 (Pubitemid 36749217)
    • (2003) Nature Medicine , vol.9 , Issue.6 , pp. 685-693
    • Jain, R.K.1
  • 30
    • 77958605259 scopus 로고    scopus 로고
    • Basic fibroblast growth factor activates MEK/ERK cell signaling pathway and stimulates the proliferation of chicken primordial germ cells
    • Choi J. W., Kim S., Kim T. M., Kim Y. M., Seo H. W., Park T. S., Jeong J. W., Song G., Han J. Y., Basic fibroblast growth factor activates MEK/ERK cell signaling pathway and stimulates the proliferation of chicken primordial germ cells PLoS One 2010 5 9
    • (2010) PLoS One , vol.5 , Issue.9
    • Choi, J.W.1    Kim, S.2    Kim, T.M.3    Kim, Y.M.4    Seo, H.W.5    Park, T.S.6    Jeong, J.W.7    Song, G.8    Han, J.Y.9
  • 31
    • 0036318855 scopus 로고    scopus 로고
    • Complementary actions of VEGF and Angiopoietin-1 on blood vessel growth and leakage
    • DOI 10.1046/j.1469-7580.2002.00061.x
    • Thurston G., Complementary actions of VEGF and Angiopoietin-1 on blood vessel growth and leakage Journal of Anatomy 2002 200 6 575 580 (Pubitemid 34823049)
    • (2002) Journal of Anatomy , vol.200 , Issue.6 , pp. 575-580
    • Thurston, G.1
  • 32
    • 0032875460 scopus 로고    scopus 로고
    • Mechanism of action and in vivo role of platelet-derived growth factor
    • Heldin C. H., Westermark B., Mechanism of action and in vivo role of platelet-derived growth factor Physiological Reviews 1999 79 4 1283 1316 (Pubitemid 29473317)
    • (1999) Physiological Reviews , vol.79 , Issue.4 , pp. 1283-1316
    • Heldin, C.-H.1    Westermark, B.2
  • 34
    • 47549110073 scopus 로고    scopus 로고
    • TGFbeta induces apoptosis and EMT in primary mouse hepatocytes independently of p53, p21Cip1 or Rb status
    • Sheahan S., Bellamy C. O., Harland S. N., Harrison D. J., Prost S., TGFbeta induces apoptosis and EMT in primary mouse hepatocytes independently of p53, p21Cip1 or Rb status BMC Cancer 2008 8, article no. 191
    • (2008) BMC Cancer , vol.8191
    • Sheahan, S.1    Bellamy, C.O.2    Harland, S.N.3    Harrison, D.J.4    Prost, S.5
  • 35
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
    • DOI 10.1016/0092-8674(94)90200-3
    • O'Reilly M. S., Holmgren L., Shing Y., Chen C., Rosenthal R. A., Moses M., Lane W. S., Cao Y., Sage E. H., Folkman J., Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma Cell 1994 79 2 315 328 (Pubitemid 24324921)
    • (1994) Cell , vol.79 , Issue.2 , pp. 315-328
    • O'Reilly, M.S.1    Holmgren, L.2    Shing, Y.3    Chen, C.4    Rosenthal, R.A.5    Moses, M.6    Lane, W.S.7    Cao, Y.8    Helene Sage, E.9    Folkman, J.10
  • 36
    • 78149484706 scopus 로고    scopus 로고
    • The orientation-dependent expression of angiostatin-endostatin hybrid proteins and their characterization for the synergistic effects of antiangiogenesis
    • Paek S. Y., Kim Y. S., Choi S. G., The orientation-dependent expression of angiostatin-endostatin hybrid proteins and their characterization for the synergistic effects of antiangiogenesis Journal of Microbiology and Biotechnology 2010 20 10 1430 1435
    • (2010) Journal of Microbiology and Biotechnology , vol.20 , Issue.10 , pp. 1430-1435
    • Paek, S.Y.1    Kim, Y.S.2    Choi, S.G.3
  • 37
    • 79955681281 scopus 로고    scopus 로고
    • Checkpoint recovery in cells: How a molecular understanding can help in the fight against cancer
    • Article no. 10
    • Medema R. H., Macrek L., Checkpoint recovery in cells: how a molecular understanding can help in the fight against cancer F1000 Biology Reports 2011 3 1, article no. 10
    • (2011) F1000 Biology Reports , vol.3 , Issue.1
    • Medema, R.H.1    MacRek, L.2
  • 38
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner M. O., The biochemistry of apoptosis Nature 2000 407 6805 770 776
    • (2000) Nature , vol.407 , Issue.6805 , pp. 770-776
    • Hengartner, M.O.1
  • 39
    • 79959196445 scopus 로고    scopus 로고
    • A trigger model of apoptosis induced by tumor necrosis factor signaling
    • Article no. 13
    • Gu C., Zhang J., Chen Y., Lei J., A trigger model of apoptosis induced by tumor necrosis factor signaling BMC Systems Biology 2011 5 1, article no. 13
    • (2011) BMC Systems Biology , vol.5 , Issue.1
    • Gu, C.1    Zhang, J.2    Chen, Y.3    Lei, J.4
  • 40
    • 33751252276 scopus 로고    scopus 로고
    • Cancer Metastasis: Building a Framework
    • DOI 10.1016/j.cell.2006.11.001, PII S0092867406014140
    • Gupta G. P., Massagué J., Cancer metastasis: building a framework Cell 2006 127 4 679 695 (Pubitemid 44781029)
    • (2006) Cell , vol.127 , Issue.4 , pp. 679-695
    • Gupta, G.P.1    Massague, J.2
  • 41
    • 33747893515 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor downregulates vascular endothelial growth factor (VEGF) expression and inhibits VEGF-VEGF receptor 2 binding in diabetic retinopathy
    • DOI 10.1677/jme.1.02008
    • Zhang S. X., Wang J. J., Gao G., Parke K., Ma J. X., Pigment epithelium-derived factor downregulates vascular endothelial growth factor (VEGF) expression and inhibits VEGF-VEGF receptor 2 binding in diabetic retinopathy Journal of Molecular Endocrinology 2006 37 1 1 12 (Pubitemid 44288601)
    • (2006) Journal of Molecular Endocrinology , vol.37 , Issue.1 , pp. 1-12
    • Zhang, S.X.1    Wang, J.J.2    Gao, G.3    Parke, K.4    Ma, J.-X.5
  • 45
    • 77953380246 scopus 로고    scopus 로고
    • Compound K inhibits basic fibroblast growth factor-induced angiogenesis via regulation of p38 mitogen activated protein kinase and AKT in human umbilical vein endothelial cells
    • Jeong A., Lee H. J., Jeong S. J., Lee H. J., Lee E. O., Bae H., Kim S. H., Compound K inhibits basic fibroblast growth factor-induced angiogenesis via regulation of p38 mitogen activated protein kinase and AKT in human umbilical vein endothelial cells Biological and Pharmaceutical Bulletin 2010 33 6 945 950
    • (2010) Biological and Pharmaceutical Bulletin , vol.33 , Issue.6 , pp. 945-950
    • Jeong, A.1    Lee, H.J.2    Jeong, S.J.3    Lee, H.J.4    Lee, E.O.5    Bae, H.6    Kim, S.H.7
  • 48
    • 34548715240 scopus 로고    scopus 로고
    • Cell cycle genes PEDF and CDKN1C in growing Deer antlers
    • Lord E. A., Martin S. K., Gray J. P., Li C., Clark D. E., Cell cycle genes PEDF and CDKN1C in growing Deer antlers Anatomical Record 2007 290 8 994 1004
    • (2007) Anatomical Record , vol.290 , Issue.8 , pp. 994-1004
    • Lord, E.A.1    Martin, S.K.2    Gray, J.P.3    Li, C.4    Clark, D.E.5
  • 50
    • 0038649218 scopus 로고    scopus 로고
    • Resistance of epiphyseal cartilage to invasion by osteosarcoma is likely to be due to expression of antiangiogenic factors
    • DOI 10.1159/000071277
    • Quan G. M. Y., Ojaimi J., Nadesapillai A. P. W., Zhou H., Choong P. F. M., Resistance of epiphyseal cartilage to invasion by osteosarcoma is likely to be due to expression of antiangiogenic factors Pathobiology 2002 70 6 361 367 (Pubitemid 36829012)
    • (2002) Pathobiology , vol.70 , Issue.6 , pp. 361-367
    • Quan, G.M.Y.1    Ojaimi, J.2    Nadesapillai, A.P.W.3    Zhou, H.4    Choong, P.F.M.5
  • 51
    • 34250352217 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor overexpression inhibits orthotopic osteosarcoma growth, angiogenesis and metastasis
    • DOI 10.1038/sj.cgt.7701044, PII 7701044
    • Ek E. T. H., Dass C. R., Contreras K. G., Choong P. F. M., Pigment epithelium-derived factor overexpression inhibits orthotopic osteosarcoma growth, angiogenesis and metastasis Cancer Gene Therapy 2007 14 7 616 626 (Pubitemid 46912035)
    • (2007) Cancer Gene Therapy , vol.14 , Issue.7 , pp. 616-626
    • Ek, E.T.H.1    Dass, C.R.2    Contreras, K.G.3    Choong, P.F.M.4
  • 52
    • 34247621392 scopus 로고    scopus 로고
    • Inhibition of orthotopic osteosarcoma growth and metastasis by multitargeted antitumor activities of pigment epithelium-derived factor
    • DOI 10.1007/s10585-007-9062-1
    • Ek E. T. H., Dass C. R., Contreras K. G., Choong P. F. M., Inhibition of orthotopic osteosarcoma growth and metastasis by multitargeted antitumor activities of pigment epithelium-derived factor Clinical and Experimental Metastasis 2007 24 2 93 106 (Pubitemid 46669247)
    • (2007) Clinical and Experimental Metastasis , vol.24 , Issue.2 , pp. 93-106
    • Ek, E.T.H.1    Dass, C.R.2    Contreras, K.G.3    Choong, P.F.M.4
  • 53
    • 33846651513 scopus 로고    scopus 로고
    • A novel orthotopic murine model provides insights into cellular and molecular characteristics contributing to human osteosarcoma
    • DOI 10.1007/s10585-006-9046-6
    • Dass C. R., Ek E. T., Contreras K. G., Choong P. F., A novel orthotopic murine model provides insights into cellular and molecular characteristics contributing to human osteosarcoma Clinical and Experimental Metastasis 2006 23 7-8 367 380 (Pubitemid 46197119)
    • (2006) Clinical and Experimental Metastasis , vol.23 , Issue.7-8 , pp. 367-380
    • Dass, C.R.1    Ek, E.T.2    Contreras, K.G.3    Choong, P.F.4
  • 54
    • 80755128482 scopus 로고    scopus 로고
    • Systemically administered PEDF against primary and secondary tumours in a clinically relevant osteosarcoma model
    • Broadhead M. L., Dass C. R., Choong P. F. M., Systemically administered PEDF against primary and secondary tumours in a clinically relevant osteosarcoma model British Journal of Cancer 2011 105 10 1503 1511
    • (2011) British Journal of Cancer , vol.105 , Issue.10 , pp. 1503-1511
    • Broadhead, M.L.1    Dass, C.R.2    Choong, P.F.M.3
  • 55
    • 77955420345 scopus 로고    scopus 로고
    • Anti-chondrosarcoma effects of PEDF mediated via molecules important to apoptosis, cell cycling, adhesion and invasion
    • Tan M. L., Choong P. F. M., Dass C. R., Anti-chondrosarcoma effects of PEDF mediated via molecules important to apoptosis, cell cycling, adhesion and invasion Biochemical and Biophysical Research Communications 2010 398 4 613 618
    • (2010) Biochemical and Biophysical Research Communications , vol.398 , Issue.4 , pp. 613-618
    • Tan, M.L.1    Choong, P.F.M.2    Dass, C.R.3
  • 56
    • 79960107886 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor blocks tumor extravasation by suppressing amoeboid morphology and mesenchymal proteolysis1,2
    • Ladhani O., Snchez-Martinez C., Orgaz J. L., Jimenez B., Volpert O. V., Pigment epithelium-derived factor blocks tumor extravasation by suppressing amoeboid morphology and mesenchymal proteolysis1,2 Neoplasia 2011 13 7 633 642
    • (2011) Neoplasia , vol.13 , Issue.7 , pp. 633-642
    • Ladhani, O.1    Snchez-Martinez, C.2    Orgaz, J.L.3    Jimenez, B.4    Volpert, O.V.5
  • 58
    • 33747602349 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor is estrogen sensitive and inhibits the growth of human ovarian cancer and ovarian surface epithelial cells
    • DOI 10.1210/en.2006-0168
    • Cheung L. W. T., Au S. C. L., Cheung A. N. Y., Ngan H. Y. S., Tombran-Tink J., Auersperg N., Wong A. S. T., Pigment epithelium-derived factor is estrogen sensitive and inhibits the growth of human ovarian cancer and ovarian surface epithelial cells Endocrinology 2006 147 9 4179 4191 (Pubitemid 44268369)
    • (2006) Endocrinology , vol.147 , Issue.9 , pp. 4179-4191
    • Cheung, L.W.T.1    Au, S.C.L.2    Cheung, A.N.Y.3    Ngan, H.Y.S.4    Tombran-Tink, J.5    Auersperg, N.6    Wong, A.S.T.7
  • 60
    • 37349015911 scopus 로고    scopus 로고
    • PEDF-derived synthetic peptides exhibit antitumor activity in an orthotopic model of human osteosarcoma
    • DOI 10.1002/jor.20434
    • Ek E. T. H., Dass C. R., Contreras K. G., Choong P. F. M., PEDF-derived synthetic peptides exhibit antitumor activity in an orthotopic model of human osteosarcoma Journal of Orthopaedic Research 2007 25 12 1671 1680 (Pubitemid 350293816)
    • (2007) Journal of Orthopaedic Research , vol.25 , Issue.12 , pp. 1671-1680
    • Ek, E.T.H.1    Dass, C.R.2    Contreras, K.G.3    Choong, P.F.M.4
  • 62
    • 43749124451 scopus 로고    scopus 로고
    • The constitutively active orphan G-protein-coupled receptor GPR39 protects from cell death by increasing secretion of pigment epithelium-derived growth factor
    • Dittmer S., Sahin M., Pantlen A., Saxena A., Toutzaris D., Pina A. L., Geerts A., Golz S., Methner A., The constitutively active orphan G-protein-coupled receptor GPR39 protects from cell death by increasing secretion of pigment epithelium-derived growth factor Journal of Biological Chemistry 2008 283 11 7074 7081
    • (2008) Journal of Biological Chemistry , vol.283 , Issue.11 , pp. 7074-7081
    • Dittmer, S.1    Sahin, M.2    Pantlen, A.3    Saxena, A.4    Toutzaris, D.5    Pina, A.L.6    Geerts, A.7    Golz, S.8    Methner, A.9


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