A zinc(II) phthalocyanine conjugated with an oxaliplatin derivative for dual chemo- and photodynamic therapy

Journal of Medicinal Chemistry

Volumn 55, Issue 11, 2012, Pages 5446-5454

  Lau, Janet T F ^a   Lo, Pui Chi ^a   Fong, Wing Ping ^a   Ng, Dennis K P ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

OXALIPLATIN; PHTHALOCYANINE ZINC; PLATINUM COMPLEX; REACTIVE OXYGEN METABOLITE; TRIETHYLENE GLYCOL;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CELL DEATH; CELL STRAIN HT29; CELL VIABILITY; CELLULAR DISTRIBUTION; COLON ADENOCARCINOMA; CONJUGATION; CYTOSTASIS; DARKNESS; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; ILLUMINATION; IN VITRO STUDY; LYSOSOME; PHOTODYNAMIC THERAPY; PHOTODYNAMICS; PHOTOSENSITIZATION; PHOTOTOXICITY; TUMOR CELL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; COORDINATION COMPLEXES; DRUG DESIGN; HT29 CELLS; HUMANS; INDOLES; LYSOSOMES; ORGANOPLATINUM COMPOUNDS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PYRIDINES; REACTIVE OXYGEN SPECIES; STRUCTURE-ACTIVITY RELATIONSHIP; ZINC;

EID: 84862291344     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm300398q     Document Type: Article

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