메뉴 건너뛰기




Volumn 21, Issue 7, 2012, Pages 1009-1017

The role of high-dose corticosteroids in the treatment of chronic lymphocytic leukemia

Author keywords

Bulky lymphadenopathy; Chronic lymphocytic leukemia; Dexamethasone; Fludarabine; Methylprednisolone; Ofatumumab; P53; Refractory disease

Indexed keywords

ACICLOVIR; ALEMTUZUMAB; BISPHOSPHONIC ACID DERIVATIVE; CHLORAMBUCIL; CIPROFLOXACIN; CORTICOTROPIN; CORTISONE; COTRIMOXAZOLE; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOXORUBICIN; FLUCONAZOLE; FLUDARABINE; GLUCOCORTICOID RECEPTOR; GRANULOCYTE COLONY STIMULATING FACTOR; HEAT SHOCK PROTEIN 90; IMMUNOGLOBULIN; ITRACONAZOLE; METHYLPREDNISOLONE; OFATUMUMAB; PREDNISOLONE; PROTEIN P53; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RITUXIMAB; VINCRISTINE;

EID: 84862287101     PISSN: 13543784     EISSN: 17447658     Source Type: Journal    
DOI: 10.1517/13543784.2012.690393     Document Type: Review
Times cited : (27)

References (69)
  • 2
    • 77949446259 scopus 로고    scopus 로고
    • Allotransplantation for chronic lymphocytic leukemia
    • Dreger P. Allotransplantation for chronic lymphocytic leukemia. Hematology Am Soc Hematol Educ Program 2009;602-9
    • (2009) Hematology Am Soc Hematol Educ Program , pp. 602-609
    • Dreger, P.1
  • 3
    • 77957664665 scopus 로고    scopus 로고
    • Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: A randomised open-label phase 3 trial
    • Hallek M, Fischer K, Fingerle-Rowson G, et al. Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: a randomised, open-label, phase 3 trial. Lancet 2010;376(9747):1164-74
    • (2010) Lancet , vol.376 , Issue.9747 , pp. 1164-1174
    • Hallek, M.1    Fischer, K.2    Fingerle-Rowson, G.3
  • 4
    • 67649600370 scopus 로고    scopus 로고
    • Treatment of fludarabine-refractory chronic lymphocytic leukemia
    • Tsimberidou AM, Keating MJ. Treatment of fludarabine-refractory chronic lymphocytic leukemia. Cancer 2009;115:2824-36
    • (2009) Cancer , vol.115 , pp. 2824-2836
    • Tsimberidou, A.M.1    Keating, M.J.2
  • 7
    • 77950502126 scopus 로고    scopus 로고
    • Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia
    • Wierda WG, Kipps TJ, Mayer J, et al. Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia. J Clin Oncol 2010;28:1749-55
    • (2010) J Clin Oncol , vol.28 , pp. 1749-1755
    • Wierda, W.G.1    Kipps, T.J.2    Mayer, J.3
  • 8
    • 33947637218 scopus 로고    scopus 로고
    • Glucocorticoid signaling: A nongenomic mechanism for T-cell immunosuppression
    • DOI 10.1016/j.molmed.2007.02.001, PII S1471491407000214
    • Lowenberg M, Verhaar AP, van den Brink GR, Hommes DW. Glucocorticoid signaling: a nongenomic mechanism for T-cell immunosuppression. Trends Mol Med 2007;13:158-63 (Pubitemid 46498830)
    • (2007) Trends in Molecular Medicine , vol.13 , Issue.4 , pp. 158-163
    • Lowenberg, M.1    Verhaar, A.P.2    Van Den Brink, G.R.3    Hommes, D.W.4
  • 9
    • 78049433704 scopus 로고    scopus 로고
    • Transcriptional control of the glucocorticoid receptor: CpG islands, epigenetics and more
    • Turner JD, Alt SR, Cao L, et al. Transcriptional control of the glucocorticoid receptor: cpG islands, epigenetics and more. Biochem Pharmacol 2010;80:1860-8
    • (2010) Biochem Pharmacol , vol.80 , pp. 1860-1868
    • Turner, J.D.1    Alt, S.R.2    Cao, L.3
  • 10
    • 18144399332 scopus 로고    scopus 로고
    • The human glucocorticoid receptor: One gene, multiple proteins and diverse responses
    • DOI 10.1016/j.steroids.2005.02.006
    • Zhou J, Cidlowski JA. The human glucocorticoid receptor: one gene, multiple proteins and diverse responses. Steroids 2005;70:407-17 (Pubitemid 40616039)
    • (2005) Steroids , vol.70 , Issue.5-7 SPEC. ISSUE , pp. 407-417
    • Zhou, J.1    Cidlowski, J.A.2
  • 12
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • Wyllie AH. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 1980;284:555-6 (Pubitemid 10070336)
    • (1980) Nature , vol.284 , Issue.5756 , pp. 555-556
    • Wyllie, A.H.1
  • 13
    • 0033982427 scopus 로고    scopus 로고
    • Therapeutically targeting lymphocyte energy metabolism by high-dose glucocorticoids
    • DOI 10.1016/S0006-2952(99)00273-7, PII S0006295299002737
    • Buttgereit F, Burmester GR, Brand MD. Therapeutically targeting lymphocyte energy metabolism by high-dose glucocorticoids. Biochem Pharmacol 2000;59:597-603. (Pubitemid 30085440)
    • (2000) Biochemical Pharmacology , vol.59 , Issue.6 , pp. 597-603
    • Buttgereit, F.1    Burmester, G.-R.2    Brand, M.D.3
  • 14
    • 34548249241 scopus 로고    scopus 로고
    • Effects of glucocorticoids on apoptosis and clearance of apoptotic cells
    • DOI 10.1100/tsw.2007.224
    • McColl A, Michlewska S, Dransfield I, Rossi AG. Effects of glucocorticoids on apoptosis and clearance of apoptotic cells. Sci World J 2007;7:1165-81 (Pubitemid 47327835)
    • (2007) TheScientificWorldJournal , vol.7 , pp. 1165-1181
    • McColl, A.1    Michlewska, S.2    Dransfield, I.3    Rossi, A.G.4
  • 15
    • 0025891044 scopus 로고
    • Characterization and purification of a functional rat glucocorticoid receptor overexpressed in a baculovirus system
    • Alnemri ES, Maksymowych AB, Robertson NM, Litwack G. Characterization and purification of a functional rat glucocorticoid receptor overexpressed in a baculovirus system. J Biol Chem 1991;266:3925-36 (Pubitemid 21909298)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.6 , pp. 3925-3936
    • Alnemri, E.S.1    Maksymowych, A.B.2    Robertson, N.M.3    Litwack, G.4
  • 16
    • 0029161862 scopus 로고
    • C-Myc and cyclin D3 (CcnD3) genes are independent targets for glucocorticoid inhibition of lymphoid cell proliferation
    • Rhee K, Bresnahan W, Hirai A, et al. c-Myc and cyclin D3 (CcnD3) genes are independent targets for glucocorticoid inhibition of lymphoid cell proliferation. Cancer Res 1995;55:4188-95
    • (1995) Cancer Res , vol.55 , pp. 4188-4195
    • Rhee, K.1    Bresnahan, W.2    Hirai, A.3
  • 17
    • 0026399712 scopus 로고
    • Similar actions of glucocorticoids and calcium on the regulation of apoptosis in S49 cells
    • Caron-Leslie LA, Cidlowski JA. Similar actions of glucocorticoids and calcium on the regulation of apoptosis in S49 cells. Mol Endocrinol 1991;5:1169-79
    • (1991) Mol Endocrinol , vol.5 , pp. 1169-1179
    • Caron-Leslie, L.A.1    Cidlowski, J.A.2
  • 18
    • 49449089908 scopus 로고    scopus 로고
    • Molecular mechanisms of corticosteroid resistance
    • Adcock IM, Barnes PJ. Molecular mechanisms of corticosteroid resistance. Chest 2008;134:394-401
    • (2008) Chest , vol.134 , pp. 394-401
    • Adcock, I.M.1    Barnes, P.J.2
  • 19
    • 0036143203 scopus 로고    scopus 로고
    • Recent insights into the mechanism of glucocorticosteroid-induced apoptosis
    • DOI 10.1038/sj.cdd.4400969
    • Distelhorst CW. Recent insights into the mechanism of glucocorticosteroidinduced apoptosis. Cell Death Differ 2002;9:6-19 (Pubitemid 34071989)
    • (2002) Cell Death and Differentiation , vol.9 , Issue.1 , pp. 6-19
    • Distelhorst, C.W.1
  • 20
    • 0032580272 scopus 로고    scopus 로고
    • Apoptosis induction by the glucocorticoid hormone dexamethasone and the calcium-ATPase inhibitor thapsigargin involves Bcl-2 regulated caspase activation
    • DOI 10.1016/S0303-7207(98)00051-3, PII S0303720798000513
    • McColl KS, He H, Zhong H, et al. Apoptosis induction by the glucocorticoid hormone dexamethasone and the calcium-ATPase inhibitor thapsigargin involves Bc1-2 regulated caspase activation. Mol Cell Endocrinol 1998;139:229-38 (Pubitemid 28340074)
    • (1998) Molecular and Cellular Endocrinology , vol.139 , Issue.1-2 , pp. 229-238
    • McColl, K.S.1    He, H.2    Zhong, H.3    Whitacre, C.M.4    Berger, N.A.5    Distelhorst, C.W.6
  • 22
    • 67549135481 scopus 로고    scopus 로고
    • Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy
    • Laane E, Tamm KP, Buentke E, et al. Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy. Cell Death Differ 2009;16:1018-29
    • (2009) Cell Death Differ , vol.16 , pp. 1018-1029
    • Laane, E.1    Tamm, K.P.2    Buentke, E.3
  • 23
    • 73449085813 scopus 로고    scopus 로고
    • Autophagy as the main means of cytotoxicity by glucocorticoids in hematological malignancies
    • Grander D, Kharaziha P, Laane E, et al. Autophagy as the main means of cytotoxicity by glucocorticoids in hematological malignancies. Autophagy 2009;5:1198-200
    • (2009) Autophagy , vol.5 , pp. 1198-1200
    • Grander, D.1    Kharaziha, P.2    Laane, E.3
  • 26
    • 79953187897 scopus 로고    scopus 로고
    • Importance of genetics in chronic lymphocytic leukemia
    • Zenz T, Mertens D, Dohner H, Stilgenbauer S. Importance of genetics in chronic lymphocytic leukemia. Blood Rev 2011;25:131-7
    • (2011) Blood Rev , vol.25 , pp. 131-137
    • Zenz, T.1    Mertens, D.2    Dohner, H.3    Stilgenbauer, S.4
  • 27
    • 67650882993 scopus 로고    scopus 로고
    • Treatment resistance in chronic lymphocytic leukemia: The role of the p53 pathway
    • Zenz T, Mohr J, Edelmann J, et al. Treatment resistance in chronic lymphocytic leukemia: the role of the p53 pathway. Leuk Lymphoma 2009;50:510-13
    • (2009) Leuk Lymphoma , vol.50 , pp. 510-513
    • Zenz, T.1    Mohr, J.2    Edelmann, J.3
  • 28
    • 79954999804 scopus 로고    scopus 로고
    • Understanding and managing ultra high-risk chronic lymphocytic leukemia
    • Stilgenbauer S, Zenz T. Understanding and managing ultra high-risk chronic lymphocytic leukemia. Hematology Am Soc Hematol Educ Program 2010;2010:481-8
    • (2010) Hematology Am Soc Hematol Educ Program , vol.2010 , pp. 481-488
    • Stilgenbauer, S.1    Zenz, T.2
  • 29
    • 77949902983 scopus 로고    scopus 로고
    • Prevention and treatment of systemic glucocorticoid side effects
    • Moghadam-Kia S, Werth VP. Prevention and treatment of systemic glucocorticoid side effects. Int J Dermatol 2010;49:239-48
    • (2010) Int J Dermatol , vol.49 , pp. 239-248
    • Moghadam-Kia, S.1    Werth, V.P.2
  • 30
    • 3042833447 scopus 로고    scopus 로고
    • Overview of the actions of glucocorticoids on the immune response: A good model to characterize new pathways of immunosuppression for new treatment strategies
    • DOI 10.1196/annals.1321.009
    • Franchimont D. Overview of the actions of glucocorticoids on the immune response: a good model to characterize new pathways of immunosuppression for new treatment strategies. Ann NY Acad Sci 2004;1024:124-37 (Pubitemid 38879597)
    • (2004) Annals of the New York Academy of Sciences , vol.1024 , pp. 124-137
    • Franchimont, D.1
  • 32
    • 0000572725 scopus 로고
    • Adrenocorticotropic hormone-and cortisone-induced regression of lymphoid tumors in man; A preliminary report
    • Pearson OH, Eliel LP, et al. Adrenocorticotropic hormone-and cortisone-induced regression of lymphoid tumors in man; a preliminary report. Cancer 1949;2:943-5
    • (1949) Cancer , vol.2 , pp. 943-945
    • Pearson, O.H.1    Eliel, L.P.2
  • 33
    • 0014494703 scopus 로고
    • Corticosteroid therapy for lymphomas and chronic lymphocytic leukemia
    • Ezdinli EZ, Stutzman L, Aungst CW, Firat D. Corticosteroid therapy for lymphomas and chronic lymphocytic leukemia. Cancer 1969;23:900-9
    • (1969) Cancer , vol.23 , pp. 900-909
    • Ezdinli, E.Z.1    Stutzman, L.2    Aungst, C.W.3    Firat, D.4
  • 34
    • 0345696332 scopus 로고
    • Weekly high-dosage glucocorticosteroid treatment of lymphocytic leukemias and lymphomas
    • Burningham RA, Restrepo A, Pugh RP, et al. Weekly high-dosage glucocorticosteroid treatment of lymphocytic leukemias and lymphomas. N Engl J Med 1964;270:1160-6
    • (1964) N Engl J Med , vol.270 , pp. 1160-1166
    • Burningham, R.A.1    Restrepo, A.2    Pugh, R.P.3
  • 35
    • 0015596378 scopus 로고
    • Chlorambucil vs. combined chlorambucil-corticosteroid therapy in chronic lymphocytic leukemia
    • Han T, Ezdinli EZ, Shimaoka K, Desai DV. Chlorambucil vs. combined chlorambucil-corticosteroid therapy in chronic lymphocytic leukemia. Cancer 1973;31:502-8
    • (1973) Cancer , vol.31 , pp. 502-508
    • Han, T.1    Ezdinli, E.Z.2    Shimaoka, K.3    Desai, D.V.4
  • 36
    • 0017730147 scopus 로고
    • Comparison of daily versus intermittent chlorambucil and prednisone therapy in the treatment of patients with chronic lymphocytic leukemia
    • Sawitsky A, Rai KR, Glidewell O, Silver RT. Comparison of daily versus intermittent chlorambucil and prednisone therapy in the treatment of patients with chronic lymphocytic leukemia. Blood 1977;50:1049-59 (Pubitemid 8245208)
    • (1977) Blood , vol.50 , Issue.6 , pp. 1049-1059
    • Sawitsky, A.1    Rai, K.R.2    Glidewell, O.3
  • 37
    • 0022347576 scopus 로고
    • Treatment of chronic lymphocytic leukemia in advanced stages. A randomized trial comparing chlorambucil plus prednisone versus cyclophosphamide, vincristine, and prednisone
    • DOI 10.1002/1097-0142(19851115)56: 10<2369::AID-CNCR2820561004>3.0. CO;2-N
    • Montserrat E, Alcala A, Parody R, et al. Treatment of chronic lymphocytic leukemia in advanced stages. A randomized trial comparing chlorambucil plus prednisone versus cyclophosphamide, vincristine, and prednisone. Cancer 1985;56:2369-75 (Pubitemid 16202426)
    • (1985) Cancer , vol.56 , Issue.10 , pp. 2369-2375
    • Montserrat, E.1    Alcala, A.2    Parody, R.3
  • 38
    • 0018187147 scopus 로고
    • The treatment of chronic lymphocytic leukemia with COP chemotherapy
    • DOI 10.1002/1097-0142(197805)41: 5<1664::AID-CNCR2820410503>3.0. CO;2-Q
    • Liepman M, Votaw ML. The treatment of chronic lymphocytic leukemia with COP chemotherapy. Cancer 1978;41:1664-9 (Pubitemid 8335371)
    • (1978) Cancer , vol.41 , Issue.5 , pp. 1664-1669
    • Liepman, M.1    Votaw, M.L.2
  • 39
    • 0035889147 scopus 로고    scopus 로고
    • Randomized comparison of fludarabine, CAP, and ChOP in 938 previously untreated stage B and C chronic lymphocytic leukemia patients
    • Leporrier M. Randomized comparison of fludarabine, CAP, and ChOP in 938 previously untreated stage B and C chronic lymphocytic leukemia patients. Blood 2001;98:2319-25
    • (2001) Blood , vol.98 , pp. 2319-2325
    • Leporrier, M.1
  • 42
    • 0027323550 scopus 로고
    • Results of fludarabine and prednisone therapy in 264 patients with chronic lymphocytic leukemia with multivariate analysis-derived prognostic model for response to treatment
    • O'Brien S, Kantarjian H, Beran M, et al. Results of fludarabine and prednisone therapy in 264 patients with chronic lymphocytic leukemia with multivariate analysis-derived prognostic model for response to treatment. Blood 1993;82:1695-700 (Pubitemid 23278758)
    • (1993) Blood , vol.82 , Issue.6 , pp. 1695-1700
    • O'Brien, S.1    Kantarjian, H.2    Beran, M.3    Smith, T.4    Koller, C.5    Estey, E.6    Robertson, L.E.7    Lerner, S.8    Keating, M.9
  • 43
    • 0034667537 scopus 로고    scopus 로고
    • Cladribine with prednisone versus chlorambucil with prednisone as first-line therapy in chronic lymphocytic leukemia: Report of a prospective, randomized, multicenter trial
    • Robak T, Blonski JZ, Kasznicki M, et al. Cladribine with prednisone versus chlorambucil with prednisone as first-line therapy in chronic lymphocytic leukemia: report of a prospective, randomized, multicenter trial. Blood 2000;96:2723-9
    • (2000) Blood , vol.96 , pp. 2723-2729
    • Robak, T.1    Blonski, J.Z.2    Kasznicki, M.3
  • 44
    • 0842301554 scopus 로고    scopus 로고
    • Pentostatin, chlorambucil and prednisone therapy for B-chronic lymphocytic leukemia: A phase I/II study by the Eastern Cooperative Oncology Group study E1488
    • DOI 10.1080/1042819031000151897
    • Oken MM, Lee S, Kay NE, et al. Pentostatin, chlorambucil and prednisone therapy for B-chronic lymphocytic leukemia: a phase I/II study by the Eastern Cooperative Oncology Group study E1488. Leuk Lymphoma 2004;45:79-84 (Pubitemid 38181397)
    • (2004) Leukemia and Lymphoma , vol.45 , Issue.1 , pp. 79-84
    • Oken, M.M.1    Lee, S.2    Kay, N.E.3    Knospe, W.4    Cassileth, P.A.5
  • 45
    • 33845805249 scopus 로고    scopus 로고
    • The multicenter trial SAKK 37/95 of cladribine, cyclophosphamide and prednisone in the treatment of chronic lymphocytic leukemias and low-grade non-Hodgkin's lymphomas
    • DOI 10.1159/000096787
    • Laurencet F, Ballabeni P, Rufener B, et al. The multicenter trial SAKK 37/95 of cladribine, cyclophosphamide and prednisone in the treatment of chronic lymphocytic leukemias and low-grade non-Hodgkin's lymphomas. Acta Haematol 2007;117:40-7 (Pubitemid 46012423)
    • (2007) Acta Haematologica , vol.117 , Issue.1 , pp. 40-47
    • Laurencet, F.1    Ballabeni, P.2    Rufener, B.3    Hess, U.4    Cerny, T.5    Fey, M.6    Luthi, J.-M.7    Plancherel, C.8    Zulian, G.B.9
  • 46
    • 0033583824 scopus 로고    scopus 로고
    • Chemotherapeutic options in chronic lymphocytic leukemia: A meta-analysis of the randomized trials
    • CLL Trialists' Collaborative Group
    • CLL Trialists' Collaborative Group. Chemotherapeutic options in chronic lymphocytic leukemia: a meta-analysis of the randomized trials. J Natl Cancer Inst 1999;91:861-8.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 861-868
  • 47
    • 33646477111 scopus 로고    scopus 로고
    • Autoimmune complications of chronic lymphocytic leukemia
    • Hamblin TJ. Autoimmune complications of chronic lymphocytic leukemia. Semin Oncol 2006;33:230-9
    • (2006) Semin Oncol , vol.33 , pp. 230-239
    • Hamblin, T.J.1
  • 48
    • 77956625856 scopus 로고    scopus 로고
    • Autoimmune complications in chronic lymphocytic leukaemia (CLL)
    • Zent CS, Kay NE. Autoimmune complications in chronic lymphocytic leukaemia (CLL). Best Pract Res Clin Haematol 2010;23:47-59
    • (2010) Best Pract Res Clin Haematol , vol.23 , pp. 47-59
    • Zent, C.S.1    Kay, N.E.2
  • 51
    • 70349390630 scopus 로고    scopus 로고
    • Dexamethasone-based therapy for childhood acute lymphoblastic leukaemia: Results of the prospective Dutch Childhood Oncology Group (DCOG) protocol ALL-9 (1997-2004)
    • Childhood Oncology Group.
    • Veerman AJ, Kamps WA, van den Berg H, et al. Childhood Oncology Group. Dexamethasone-based therapy for childhood acute lymphoblastic leukaemia: results of the prospective Dutch Childhood Oncology Group (DCOG) protocol ALL-9 (1997-2004). Lancet Oncol 2009;10:957-66
    • (2009) Lancet Oncol , vol.10 , pp. 957-966
    • Veerman, A.J.1    Kamps, W.A.2    Van Den Berg, H.3
  • 53
    • 0029094664 scopus 로고
    • Methylprednisolone in advanced chronic lymphocytic leukaemia: Rationale for, and effectiveness of treatment suggested by DiSC assay
    • Bosanquet AG, McCann SR, Crotty GM, et al. Methylprednisolone in advanced chronic lymphocytic leukaemia: rationale for, and effectiveness of treatment suggested by DiSC assay. Acta Haematol 1995;93:73-9.
    • (1995) Acta Haematol , vol.93 , pp. 73-79
    • Bosanquet, A.G.1    McCann, S.R.2    Crotty, G.M.3
  • 56
    • 77955713977 scopus 로고    scopus 로고
    • High-dose methylprednisolone can induce remissions in patients with fludarabine-refractory chronic lymphocytic leukaemia
    • Xu W, Miao KR, Hong M, et al. High-dose methylprednisolone can induce remissions in patients with fludarabine-refractory chronic lymphocytic leukaemia. Eur J Cancer 2010;46:2145-9
    • (2010) Eur J Cancer , vol.46 , pp. 2145-2149
    • Xu, W.1    Miao, K.R.2    Hong, M.3
  • 57
    • 0036721023 scopus 로고    scopus 로고
    • Glucocorticoids and rituximab in vitro: Synergistic direct antiproliferative and apoptotic effects
    • Rose AL, Smith BE, Maloney DG. Glucocorticoids and rituximab in vitro: synergistic direct antiproliferative and apoptotic effects. Blood 2002;100:1765-73 (Pubitemid 34925155)
    • (2002) Blood , vol.100 , Issue.5 , pp. 1765-1773
    • Rose, A.L.1    Smith, B.E.2    Maloney, D.G.3
  • 58
    • 37149029392 scopus 로고    scopus 로고
    • Methylprednisolone-rituximab is an effective salvage therapy for patients with relapsed chronic lymphocytic leukemia including those with unfavorable cytogenetic features
    • DOI 10.1080/10428190701724801, PII 788239125
    • Bowen DA, Call TG, Jenkins GD, et al. Methylprednisolone-rituximab is an effective salvage therapy for patients with relapsed chronic lymphocytic leukemia including those with unfavorable cytogenetic features. Leuk Lymphoma 2007;48:2412-17 (Pubitemid 350253473)
    • (2007) Leukemia and Lymphoma , vol.48 , Issue.12 , pp. 2412-2417
    • Bowen, D.A.1    Call, T.G.2    Jenkins, G.D.3    Zent, C.Z.4    Schwager, S.M.5    Van Dyke, D.L.6    Jelinek, D.F.7    Kay, N.E.8    Shanafelt, T.D.9
  • 59
    • 40849094878 scopus 로고    scopus 로고
    • High dose methylprednisolone and rituximab is an effective therapy in advanced refractory chronic lymphocytic leukemia resistant to fludarabine therapy
    • DOI 10.3324/haematol.11903
    • Dungarwalla M, Evans SO, Riley U, et al. High dose methylprednisolone and rituximab is an effective therapy in advanced refractory chronic lymphocytic leukemia resistant to fludarabine therapy. Haematologica 2008;93(3):475-6 (Pubitemid 351398657)
    • (2008) Haematologica , vol.93 , Issue.3 , pp. 475-476
    • Dungarwalla, M.1    Evans, S.O.2    Riley, U.3    Catovsky, D.4    Dearden, C.E.5    Matutes, E.6
  • 60
    • 56249095457 scopus 로고    scopus 로고
    • Rituximab in combination with high-dose methylprednisolone for the treatment of fludarabine refractory high-risk chronic lymphocytic leukemia
    • Castro JE, Sandoval-Sus JD, Bole J, et al. Rituximab in combination with high-dose methylprednisolone for the treatment of fludarabine refractory high-risk chronic lymphocytic leukemia. Leukemia 2008;22:2048-53
    • (2008) Leukemia , vol.22 , pp. 2048-2053
    • Castro, J.E.1    Sandoval-Sus, J.D.2    Bole, J.3
  • 61
    • 79957456534 scopus 로고    scopus 로고
    • Dose-dense high-dos methylprednisolone and rituximab in the treatment of relapsed orrefractory high-risk chronic lymphocytic leukemia
    • Pileckyte R, Jurgutis M, Valceckiene V, et al. Dose-dense high-dos methylprednisolone and rituximab in the treatment of relapsed orrefractory high-risk chronic lymphocytic leukemia. Leuk Lymphoma 2011;52:1055-65
    • (2011) Leuk Lymphoma , vol.52 , pp. 1055-1065
    • Pileckyte, R.1    Jurgutis, M.2    Valceckiene, V.3
  • 63
    • 0021322023 scopus 로고
    • Effective treatment of advanced multiple myeloma refractory to alkylating agents
    • Barlogie B, Smith L, Alexanian R. Effective treatment of advanced multiple myeloma refractory to alkylating agents. N Engl J Med 1984;24310:1353-6 (Pubitemid 14149087)
    • (1984) New England Journal of Medicine , vol.310 , Issue.21 , pp. 1353-1356
    • Barlogie, B.1    Smith, L.2    Alexanian, R.3
  • 64
    • 55049110133 scopus 로고    scopus 로고
    • Efficacy of rituximab in combination with steroids in refractory chronic lymphocytic leukemia
    • Quinn JP, Mohamedbhai S, Chipperfield K, et al. Efficacy of rituximab in combination with steroids in refractory chronic lymphocytic leukemia. Leuk Lymphoma 2008;49:1995-8.
    • (2008) Leuk Lymphoma , vol.49 , pp. 1995-1998
    • Quinn, J.P.1    Mohamedbhai, S.2    Chipperfield, K.3
  • 65
    • 83255170348 scopus 로고    scopus 로고
    • Ofatumumab and high-dose methylprednisolone is an effective salvage treatment for heavily pretreated, unfit or refractory patients with chronic lymphocytic leukemia: Single institution experience
    • Castro JE, Barajas-Gamboa JS, Melo-Cardenas J, et al. Ofatumumab and high-dose methylprednisolone is an effective salvage treatment for heavily pretreated, unfit or refractory patients with chronic lymphocytic leukemia: single institution experience. ASH Annual Meeting Abstracts 2010;116:4638
    • (2010) ASH Annual Meeting Abstracts , vol.116 , pp. 4638
    • Castro, J.E.1    Barajas-Gamboa, J.S.2    Melo-Cardenas, J.3
  • 66
    • 84872486370 scopus 로고    scopus 로고
    • Efficacy of ofatumumab and high-dose methylprednisolone for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL)
    • Teichman ML, Ho VQ, Balducci L, et al. Efficacy of ofatumumab and high-dose methylprednisolone for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL). ASH Annual Meeting Abstracts 2011;118:4619
    • (2011) ASH Annual Meeting Abstracts , vol.118 , pp. 4619
    • Teichman, M.L.1    Ho, V.Q.2    Balducci, L.3
  • 67
    • 84862296694 scopus 로고    scopus 로고
    • Oral high-dose glucocorticoids and Ofatumumab in fludarabine-resistant chronic lymphocytic leukemia
    • [Epub ahead of print]
    • Spaner DE. Oral high-dose glucocorticoids and Ofatumumab in fludarabine-resistant chronic lymphocytic leukemia. Leukemia 2011: [Epub ahead of print]
    • (2011) Leukemia
    • Spaner, D.E.1
  • 68
    • 85044557864 scopus 로고    scopus 로고
    • Alemtuzumab in combination with high-dose methylprednisolone is a logical, feasible and highly active therapeutic regimen in chronic lymphocytic leukaemia patients with p53 defects
    • Pettitt AR, Matutes E, Oscier D. Alemtuzumab in combination with high-dose methylprednisolone is a logical, feasible and highly active therapeutic regimen in chronic lymphocytic leukaemia patients with p53 defects. Leukemia 2006;201:441-5.
    • (2006) Leukemia , vol.201 , pp. 441-445
    • Pettitt, A.R.1    Matutes, E.2    Oscier, D.3
  • 69
    • 84861343178 scopus 로고    scopus 로고
    • Alemtuzumab plus oral dexamethasone, followed by alemtuzumab maintenance or allogeneic transplantation in ultra high-risk CLL: Interim Analysis of a Phase II Study of the GCLLSG and fcgcll/MW
    • Stilgenbauer S, Cymbalista F, Leblond V, et al. Alemtuzumab plus oral dexamethasone, followed by alemtuzumab maintenance or allogeneic transplantation in ultra high-risk CLL: interim Analysis of a Phase II Study of the GCLLSG and fcgcll/MW. ASH Annual Meeting Abstracts 2011;118:2854
    • (2011) ASH Annual Meeting Abstracts , vol.118 , pp. 2854
    • Stilgenbauer, S.1    Cymbalista, F.2    Leblond, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.