High-level mucosal and systemic immune responses induced by oral administration with Lactobacillus-expressed porcine epidemic diarrhea virus (PEDV) S1 region combined with Lactobacillus-expressed N protein

Applied Microbiology and Biotechnology

Volumn 93, Issue 6, 2012, Pages 2437-2446

  Di Qiu, Liu ^a   Jun Wei, Ge ^a   Xin Yuan, Qiao ^a   Yan Ping, Jiang ^a   Song Mei, Liu ^a   Yi Jing, Li ^a  

^a NORTHEAST AGRICULTURAL UNIVERSITY   (China)

Author keywords

Combined intragastric immunization; Lactobacillus casei; N protein and S1 region; Porcine epidemic diarrhea virus

Indexed keywords

DNA FRAGMENT; ELECTROTRANSFORMATION; IMMUNE RESPONSE; IMMUNOGENICITY; IN-VITRO; INTRAGASTRIC ADMINISTRATION; LACTOBACILLUS CASEI; MUCOSAL VACCINE; NEGATIVE CONTROL; NUCLEOCAPSIDS; ORAL ADMINISTRATION; PORCINE EPIDEMIC DIARRHEA VIRUS; RECOMBINANT STRAINS; SPIKE PROTEIN; SPLENOCYTES;

EPIDEMIOLOGY; IMMUNIZATION; IMMUNOLOGY; MAMMALS; MIXTURES; VIRUSES;

RECOMBINANT PROTEINS;

DNA FRAGMENT; GAMMA INTERFERON; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 4; NUCLEOCAPSID PROTEIN; PLASMID DNA; SECRETORY IMMUNOGLOBULIN; VIRUS VACCINE; VITRONECTIN; MEMBRANE PROTEIN; NUCLEOCAPSID PROTEIN, CORONAVIRUS; SPIKE GLYCOPROTEIN, CORONAVIRUS; VIRUS ENVELOPE PROTEIN;

BACTERIUM; BIOENGINEERING; CYTOLOGY; DIARRHEAL DISEASE; DRUG DEVELOPMENT; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNIZATION; INDUCED RESPONSE; MEDICINE; MUCUS; PLASMID; PROTEIN; RODENT; TRANSFORMATION; VACCINE; VIRUS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN PRESENTING CELL; ARTICLE; CELL LYSATE; CONTROLLED STUDY; CYTOKINE RESPONSE; ELECTROTRANSFORMATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; FEMALE; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNOPROPHYLAXIS; IN VITRO STUDY; INTESTINE FLUID; LACTOBACILLUS CASEI; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PORCINE EPIDEMIC DIARRHEA VIRUS; PROTEIN EXPRESSION; RECOMBINANT PLASMID; SHUTTLE VECTOR; SPLEEN CELL; VIRUS NUCLEOCAPSID; ANIMAL; ANIMAL DISEASE; BAGG ALBINO MOUSE; CORONAVIRUS INFECTION; GENE EXPRESSION; GENETICS; IMMUNOLOGY; LACTOBACILLUS; METABOLISM; ORAL DRUG ADMINISTRATION; SWINE; SWINE DISEASE; VIROLOGY;

LACTOBACILLUS; LACTOBACILLUS CASEI; MUS; PORCINE EPIDEMIC DIARRHEA VIRUS;

ADMINISTRATION, ORAL; ANIMALS; CORONAVIRUS INFECTIONS; FEMALE; GENE EXPRESSION; IMMUNITY, MUCOSAL; LACTOBACILLUS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; NUCLEOCAPSID PROTEINS; PORCINE EPIDEMIC DIARRHEA VIRUS; SWINE; SWINE DISEASES; VIRAL ENVELOPE PROTEINS; VIRAL VACCINES;

EID: 84862286708     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3734-0     Document Type: Article

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