Low-grade, low-stage endometrioid endometrial adenocarcinoma: A clinicopathologic analysis of 324 cases focusing on frequency and pattern of myoinvasion

International Journal of Gynecological Pathology

Volumn 31, Issue 4, 2012, Pages 337-343

  Quick, Charles M ^a   May, Taymaa ^a   Horowitz, Neil S ^a   Nucci, Marisa R ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Endometrioid carcinoma; Invasion; Low grade; Outcome; Pattern

Indexed keywords

ADENOMA; ADENOMYOSIS; ADULT; AGED; ARTICLE; CANCER GRADING; CANCER GROWTH; CANCER INFILTRATION; CANCER INVASION; CANCER RECURRENCE; CANCER STAGING; CORRELATION ANALYSIS; ENDOMETRIUM CARCINOMA; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; HYSTERECTOMY; LYMPH VESSEL METASTASIS; LYMPHADENECTOMY; MAJOR CLINICAL STUDY; MYOMETRIUM; OUTCOME ASSESSMENT; PATIENT IDENTIFICATION; PRIORITY JOURNAL; SALPINGOOOPHORECTOMY;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, ENDOMETRIOID; ENDOMETRIAL NEOPLASMS; FEMALE; HISTOCYTOCHEMISTRY; HUMANS; MIDDLE AGED; MYOMETRIUM; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; RETROSPECTIVE STUDIES;

EID: 84862280029     PISSN: 02771691     EISSN: 15387151     Source Type: Journal    
DOI: 10.1097/PGP.0b013e31823ff422     Document Type: Article

References (21)

1. Ries LAG, Melbert D, Krapcho M, et al, eds. SEER Cancer Statistics Review, 1975-2005. Bathesda National Cancer Institute. 2008; Online.
2. De Palo G, Kenda R, Andreola A, et al. Endometrial carcinoma: stage I. A retrospective analysis of 262 patients. Obstet Gynecol 1982;60:225-31.
3. Abeler VM, Kjorstad KE. Endometrial adenocarcinoma in Norway: A study of a total population. Cancer 1991;67:3093-103.
4. Abeler VM, Kjorstad KE, Berle E. Carcinoma of the endometrium in Norway: A histopathological and prognostic survey of a total population. Int J Gynecol Cancer 1992;2:9-22.
5. Cornelison TL, Trimble EL, Kosary CL. SEER data, corpus uteri cancer: Treatment trends versus survival for FIGO stage II, 1988-1994. Gynecol Oncol 1999;74:35-355.
6. Chan JK, Kapp DS, Cheung MK, et al. Prognostic factors and risk of extrauterine metastases in 3867 women with grade 1 endometrioid corpus cancer. Am J Obstet Gynecol 2008;198: 216.e1-5.
7. Sorbe Nordstram B, Maenpaa J, Kuhelj J, et al. Intravaginal brachytherapy in FIBO stage I low-risk endometrial cancer: A controlled randomized study. Int J Gynecol Cancer 2009;19:873-8.
8. Murray SK, Young RH, Scully RE. Unusual epithelial and stromal changes in myoinvasive endometrioid adenocarcinoma: A study of their frequency, associated diagnostic problems, and prognostic significance. Int J Gynecol Pathol 2003;22: 324-33.
9. Longacre TA, Hendrickson MR. Diffusely infiltrative endometrial adenocarcinoma. Am J Surg Pathol 1999;23:69-78.
10. Eichhorn JH, Young RH, Clement PB. Sertoliform endometrial adenocarcinoma: A study of four cases. Int J Gynecol Pathol 1996;15:119-126.
11. Murray SK, Young RH, Scully RE. Uterine endometrioid carcinoma with small nonvillous papillae: An analysis of 26 cases of a favorable-prognosis tumor to be distinguished from serous carcinoma. Int J Surg Pathol 2000;8:279-89.
12. Murray SK, Clement PB, Young RH. Endometrioid carcinomas of the uterine corpus with sex cord-like formations, hyalinization, and other unusual morphologic features: A report of 31 cases of a neoplasm that may be confused with carcinosarcoma and other uterine neoplasms. Am J Surg Pathol 2005;29:157-166.
13. Clement PB, Young RH. Endometrioid carcinoma of the uterine corpus: A review of its pathology with emphasis on recent advances and problematic aspects. Adv Anat Pathol 2002;9:145-84.
14. Crum CP, Nucci MR, Lee KR, eds. Diagnostic Gynecologic Surgical Pathology. Philadelphia; Elsevier Saunders.
15. Kurman RJ, Norris HJ. Evaluation of criteria for distinguishing atypical endometrial hyperplasia from well-differentiated carcinoma. Cancer 1982;49:2547-59.
16. Del Carmen MG, Boruta DM, Shorge JO. Recurrent endometrial cancer. Clin Obstet Gynecol 2011;53:266-77.
17. Gadducci A, Cosio S, Fanucchi A, et al. An intensive followup does not change survival of patients with clinical stage I endometrial cancer. Anticancer Res 2000;20:(3B): 1977-84.
18. Ali A, Black D, Soslow RA. Difficulties in assessing the depth of myometrial invasion in endometrial carcinoma. Int J Surg Pathol 2007;26:115-23.
19. Kizer NT, Gao F, Guntupalli S, et al. Lower uterine segment involvement is associated with poor outcomes in early-stage endometrioid endometrial carcinoma. Ann Surg Oncol 2011; 18:1419-24.
20. Chen S, Leitao MM, Tornos C, et al. Invasion patterns in stage I endometrioid and mucinous ovarian carcinomas: A clinicopathologic analysis emphasizing favorable outcomes in carcinomas without destructive stromal invasion and the occasional malignant course of carcinomas with limited destructive stromal invasion. Mod Pathol 2005;18:903-11.
21. Ambrose RA, Kurman RJ. Combined assessment of vascular and myometrial invasion as a model to predict prognosis in stage I endometrioid adenocarcinoma of the uterine corpus. Cancer 1992;69:1424-31.