Electrophysiological models for the heterogeneous canine atria: Computational platform for studying rapid atrial arrhythmias

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

Volumn , Issue , 2011, Pages 1693-1696

  Aslanidi, Oleg V ^a   Butters, Timothy D ^a   Ren, Christopher X ^a   Ryecroft, Gareth ^a   Zhang, Henggui ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTION POTENTIALS; ATRIAL ARRHYTHMIA; ATRIAL CELLS; COMPUTATIONAL PLATFORMS; CONDUCTION BLOCK; ELECTROPHYSIOLOGICAL MODELS; LEFT ATRIUMS; NEW MODEL; PULMONARY VEINS; RAPID PACING;

ELECTRIC PROPERTIES; ELECTROPHYSIOLOGY; SUBSTRATES; TISSUE;

MODELS;

ACTION POTENTIAL; ANIMAL; ARTICLE; BIOLOGICAL MODEL; COMPUTER SIMULATION; DOG; HEART ATRIUM; HEART ATRIUM FIBRILLATION; HEART MUSCLE CONDUCTION SYSTEM; PATHOPHYSIOLOGY; PULMONARY VEIN;

ACTION POTENTIALS; ANIMALS; ATRIAL FIBRILLATION; COMPUTER SIMULATION; DOGS; HEART ATRIA; HEART CONDUCTION SYSTEM; MODELS, CARDIOVASCULAR; PULMONARY VEINS;

EID: 84862252308     PISSN: 1557170X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/IEMBS.2011.6090486     Document Type: Conference Paper

References (23)

1. E. Anter E, M. Jessup, and D.J. Callans. "Atrial fibrillation and heart failure: treatment considerations for a dual epidemic." Circulation, vol. 119, pp. 2516-2525, 2009.
2. E.J. Benjamin, P.A. Wolf, R.B. D'Agostino, et al. "Impact of atrial fibrillation on the risk of death: the Framingham Heart Study." Circulation, vol. 98, pp. 946-952, 1998.
3. P.A. Wolf, R.D. Abbott, and W.B. Kannel. "Atrial fibrillation as an independent risk factor for stroke: the Framingham Study." Stroke, vol. 22, pp. 983-988, 1991.
4. A. Harada, K. Sasaki, T. Fukushima, et al. "Atrial activation during chronic atrial fibrillation in patients with isolated mitral valve disease." Ann. Thorac. Surg., vol. 61, pp. 104-111, 1996.
5. S. Nattel, A. Shiroshita-Takeshita, B.J. Brundel, and L. Rivard. "Mechanisms of atrial fibrillation: lessons from animal models." Prog. Cardiovasc. Dis., vol. 48, pp. 9-28, 2005.
6. J. Jalife, O. Berenfeld, and M. Mansour. "Mother rotors and fibrillatory conduction: a mechanism of atrial fibrillation." Cardiovasc. Res., vol. 54, pp. 204-16, 2002.
7. M.S. Spach, P.C. Dolber, and J.F. Heidlage. "Interaction of inhomogeneities of repolarization with anisotropic propagation in dog atria: a mechanism for both preventing and initiating reentry." Circ. Res., vol. 65, pp. 1612-1631, 1989.
8. D. Li, L. Zhang, J. Kneller, and S. Nattel. "Potential ionic mechanism for repolarization differences between canine right and left atrium." Circ. Res., vol. 88, pp. 1168-1175, 2001.
9. J.R. Ehrlich, T.J. Cha, L. Zhang, D. Chartier, L. Villeneuve, T.E. Hebert, and S. Nattel. "Characterization of a hyperpolarizationactivated time-dependent potassium current in canine cardiomyocytes from pulmonary vein myocardial sleeves and left atrium." J. Physiol., vol. 557, pp. 583-597, 2004.
10. R.J. Ramirez, S. Nattel, and M. Courtemanche. "Mathematical analysis of canine atrial action potentials: rate, regional factors, and electrical remodeling." Am. J. Physiol., vol. 279, pp. H1767-85, 2000.
11. Y. Rudy. "From genome to physiome: integrative models of cardiac excitation." Ann. Biomed. Eng, vol. 28, pp. 945-950, 2000.
12. O.V. Aslanidi, M.R. Boyett, H. Dobrzynski, J. Li, and H. Zhang. "Mechanisms of transition from normal to reentrant electrical activity in a model of rabbit atrial tissue: interaction of tissue heterogeneity and anisotropy." Biophys. J., vol. 96, pp. 798-817, 2009.
13. O.V. Aslanidi, R. Robinson, D. Cheverton, M.R. Boyett, and H. Zhang. "Electrophysiological substrate for a dominant reentrant source during atrial fibrillation." In Conf. Proc. 2009 IEEE Eng. Med. Biol. Soc., pp. 2819-2822.
14. F. Ravelli, and M. Allessie. "Effects of atrial dilatation on refractory period and vulnerability to atrial fibrillation in the isolated Langendorff-perfused rabbit heart." Circulation, vol. 96, pp. 1686-1695, 1997.
15. A. Burashnikov, S. Mannava, and C. Antzelevitch. "Transmembrane action potential heterogeneity in the canine isolated arterially perfused right atrium: effect of IKr and IKur/Ito block." Am. J. Physiol., vol. 286, pp. H2393-400, 2004.
16. Y.J. Chen, S.A. Chen, M.S. Chang, and C.I. Lin. "Arrhythmogenic activity of cardiac muscle in pulmonary veins of the dog: implication for the genesis of atrial fibrillation." Cardiovasc. Res., vol. 48, pp. 265-273, 2000.
17. D. O'Donnell, J.P. Bourke, and S.S. Furniss. "Interatrial transseptal electrical conduction: comparison of patients with atrial fibrillation and normal controls." J. Cardiovasc. Electrophysiol., vol. 13, pp. 1111-1117, 2002.
18. O.V. Aslanidi, P. Stewart, M.R. Boyett, and H. Zhang. "Optimal velocity and safety of discontinuous conduction through the heterogeneous Purkinje-ventricular junction." Biophys. J., vol. 97, pp. 20-39, 2009.
19. S. Sakamoto, T. Nitta, Y. Ishii, Y. Miyagi, H. Ohmori, and K. Shimizu. "Interatrial electrical connections: the precise location and preferential conduction." J. Cardiovasc. Electrophysiol., vol. 16, pp. 1077-1186, 2005.
20. J. Sahadevan, K. Ryu, L. Peltz., et al. "Epicardial mapping of chronic atrial fibrillation in patients: preliminary observations." Circulation, vol. 110, pp. 3293-3299, 2004.
21. R. Arora, S. Verheule, L. Scott, et al. "Arrhythmogenic substrate of the pulmonary veins assessed by high-resolution optical mapping." Circulation, vol. 107, pp. 1816-1821, 2003.
22. G. Seemann, C. Hoper, F.B. Sachse, O. Dossel, A.V. Holden, and H. Zhang. "Heterogeneous three-dimensional anatomical and electrophysiological model of human atria." Phil. Trans. Roy. Soc. A, vol. 364, pp. 1465-1481, 2006.
23. M. Ridler, D.M. McQueen, C.S. Peskin, and E. Vigmond. "Action potential duration gradient protects the right atrium from fibrillating." In Conf. Proc. 2006 IEEE Eng. Med. Biol. Soc., pp. 3978-3981.