Endothelial cell function in patients with hereditary angioedema: Elevated soluble E-selectin level during inter-attack periods

Journal of Clinical Immunology

Volumn 32, Issue 1, 2012, Pages 61-69

  Czícz, Judit ^a   Schaffer, Gyula ^a   Csuka, Dorottya ^a   Walentin, Szilvia ^b   Kunde, Jan ^c   Prohászka, Zoltán ^d   Farkas, Henriette ^a   Cervenak, László ^d  

^a SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c THERMO FISHER SCIENTIFIC   (Germany)

^d INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

C1 inhibitor; E selectin; Endothelial function; Hereditary angioedema

Indexed keywords

C REACTIVE PROTEIN; COLLAGEN; COMPLEMENT COMPONENT C1S INHIBITOR; DANAZOL; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ENDOTHELIN 1; VON WILLEBRAND FACTOR; BIOLOGICAL MARKER;

ADULT; AGE; ANGIONEUROTIC EDEMA; ARTICLE; BLOOD GROUP ABO SYSTEM; CELL FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE MARKER; ENDOTHELIAL CELL FUNCTION; ENDOTHELIUM CELL; FEMALE; GENDER; HUMAN; MALE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN INTERACTION; SMOKING; BLOOD; CASE CONTROL STUDY; KINETICS; METABOLISM; MIDDLE AGED;

ADULT; ANGIOEDEMAS, HEREDITARY; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; COMPLEMENT C1 INHIBITOR PROTEIN; E-SELECTIN; ENDOTHELIAL CELLS; FEMALE; HUMANS; KINETICS; MALE; MIDDLE AGED;

EID: 84862240839     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-011-9606-7     Document Type: Article

References (38)

1. Nzeako UC, Frigas E, Tremaine WJ. Hereditary angioedema: A broad review for clinicians. Arch Intern Med. 2001;161:2417-29. (Pubitemid 33043115)
2. Agostoni A, Aygören-Pürsün E, Binkley KE, Blanch A, Bork K, et al. Hereditary and acquired angioedema: Problems and progress: Proceedings of the third C1 esterase inhibitor deficiency workshop and Beyond. J Allergy Clin Immunol. 2004;114:S51-S131.doi:10.1016/j.jaci.2004.06.047. (Pubitemid 39200689)
3. Agostoni A, Cicardi M. Hereditary and acquired C1-inhibitor deficiency: biological and clinical characteristics in 235 patients. Medicine (Baltimore). 1992;71:206-15.
4. Bork K, Meng G, Staubach P, Hardt J. Hereditary angioedema: New findings concerning symptoms, affected organs, and course. Am J Med. 2006;119:267-74.doi: 10.1016/j.amjmed.2005.09.064. (Pubitemid 43255068)
5. Farkas H. Management of upper airway edema caused by hereditary angioedema. Allergy Asthma Clin Immunol. 2010;6:19.doi:10.1186/1710-1492-6-19.
6. Frank MM. Complement disorders and hereditary angioedema. J Allergy Clin Immunol. 2010;125:S262-71. doi:10.1016/j.jaci.2009.10.063.
7. Bowen T, Brosz J, Brosz K, Hebert J, Ritchie B. Management of hereditary angioedema: 2010 Canadian approach. Allergy Asthma Clin Immunol. 2010;6:20. doi:10.1186/1710-1492-6-20.
8. Zuraw BL. HAE therapies: past present and future. Allergy Asthma Clin Immunol. 2010;6:23. doi:10.1186/1710-1492-6-23.
9. Bygum A, Fagerberg CR, Ponard D, Monnier N, Lunardi J, et al. Mutational spectrum and phenotypes in Danish families with hereditary angioedema because of C1 inhibitor deficiency. Allergy. 2011;66:76-84. doi:10.1111/j.1398-9995.2010. 02456.x.
10. Davis AE. The pathophysiology of hereditary angioedema. Clin Immunol. 2005;114:3-9. doi:10.1016/j.clim.2004.05.007. (Pubitemid 39646476)
11. Sumpio BE, Riley JT, Dardik A. Cells in focus: endothelial cell. Int J Biochem Cell Biol. 2002;34:1508-12.
12. Constans J, Conri C. Circulating markers of endothelial function in cardiovascular disease. Clin Chim Acta. 2006;368:33-47. doi:10.1016/j.cca.2005. 12.030. (Pubitemid 43792418)
13. Roldán V, Marín F, Lip GYH, Blann AD. Soluble E-selectin in cardiovascular disease and its risk factors. A review of the literature. Thromb Haemost. 2003;90:1007-20. doi:10.1267/THRO03061007. (Pubitemid 38004418)
14. Pigott R, Dillon LP, Hemingway IH, Gearing AJ. Soluble forms of E-selectin, ICAM-1 and VCAM-1 are present in the supernatants of cytokine activated cultured endothelial cells. Biochem Biophys Res Commun. 1992;187:584-9.
15. Masaki T. Possible role of endothelin in endothelial regulation of vascular tone. Annu Rev Pharmacol Toxicol. 1995;35:235-55. doi:10.1146/annurev. pa.35.040195.001315.
16. Lip GY, Blann A. von Willebrand factor: A marker of endothelial dysfunction in vascular disorders? Cardiovasc Res. 1997;34:255-65. (Pubitemid 27241568)
17. Bowen T, Cicardi M, Farkas H, Bork K, Longhurst HJ, et al. 2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema. Allergy Asthma Clin Immunol. 2010;6:24. doi:10.1186/1710-1492-6-24.
18. Bowen T, Cicardi M, Bork K, Zuraw B, Frank M, et al. Hereditary angiodema: a current state-of-the-art review, VII: Canadian Hungarian 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema. Ann Allergy Asthma Immunol. 2008;100:S30-40.
19. Papassotiriou J, Morgenthaler NG, Struck J, Alonso C, Bergmann A. Immunoluminometric assay for measurement of the C-terminal endothelin-1 precursor fragment in human plasma. Clin Chem. 2006;52:1144-51. doi:10.1373/clinchem.2005.065581. (Pubitemid 43794428)
20. Thorand B, Baumert J, Döring A, Schneider A, Chambless L, et al. Association of cardiovascular risk factors with markers of endothelial dysfunction in middle-aged men and women. Results from the MONICA/KORA Augsburg Study. Thromb Haemost. 2006;95:134-41.
21. Bermudez EA, Rifai N, Buring JE, Manson JE, Ridker PM. Relation between markers of systemic vascular inflammation and smoking in women. Am J Cardiol. 2002;89:1117-9. (Pubitemid 34462860)
22. Paterson AD, Lopes-Virella MF, Waggott D, Boright AP, Hosseini SM, et al. Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble Eselectin. Arterioscler Thromb Vasc Biol. 2009;29:1958-67. doi:10.1161/ATVBAHA.109.192971.
23. Cai S, Davis AE. Complement regulatory protein C1 inhibitor binds to selectins and interferes with endothelial-leukocyte adhesion. J Immunol. 2003;171:4786-91. (Pubitemid 37310598)
24. Cai S, Dole VS, Bergmeier W, Scafidi J, Feng H, et al. A direct role for C1 inhibitor in regulation of leukocyte adhesion. J Immunol. 2005;174:6462-6. (Pubitemid 40663841)
25. Edgar JDM, Gabriel V, Gallimore JR, McMillan SA, Grant J. A prospective study of the sensitivity, specificity and diagnostic performance of soluble intercellular adhesion molecule 1, highly sensitive C-reactive protein, soluble E-selectin and serum amyloid A in the diagnosis of neonatal infection. BMC Pediatr. 2010;10:22. doi:10.1186/1471-2431-10-22.
26. Reynolds HR, Buyon J, Kim M, Rivera TL, Izmirly P, et al. Association of plasma soluble E-selectin and adiponectin with carotid plaque in patients with systemic lupus erythematosus. Atherosclerosis. 2010;210:569-74. doi:10.1016/j.atherosclerosis.2009.12.007.
27. Nasuno A, Matsubara T, Hori T, Higuchi K, Imai S, et al. Levels of soluble E-selectin and ICAM-1 in the coronary circulation of patients with stable coronary artery disease: Association with the severity of coronary atherosclerosis. Jpn Heart J. 2002;43:93-101. (Pubitemid 41518848)
28. Suefuji H, Ogawa H, Yasue H, Sakamoto T, Miyao Y, et al. Increased plasma level of soluble E-selectin in acute myocardial infarction. Am Heart J. 2000;140:243-8. doi:10.1067/mhj.2000.107544. (Pubitemid 30641586)
29. Stancanelli B, Malatino LS, Cataliotti A, Bellanuova I, Mallamaci F, et al. Soluble e-selectin is an inverse and independent predictor of left ventricular wall thickness in endstage renal disease patients. Nephron Clin Pract. 2010;114:c74-80. doi:10.1159/000252806.
30. Hayashi S, Abe K, Matsuoka H, Goya S, Morishita H, et al. Increased level of soluble E-selectin in the serum from patients with idiopathic pulmonary fibrosis. Inflammation. 2004;28:1-5. (Pubitemid 38249273)
31. Széplaki G, Varga L, Valentin S, Kleiber M, Karádi I, et al. Adverse effects of danazol prophylaxis on the lipid profiles of patients with hereditary angioedema. J Allergy Clin Immunol. 2005;115:864-9. doi:10.1016/j.jaci.2004.12.1130. (Pubitemid 40460866)
32. Szegedi R, Széplaki G, Varga L, Prohászka Z, Széplaki Z, et al. Long-term danazol prophylaxis does not lead to increased carotid intima-media thickness in hereditary angioedema patients. Atherosclerosis. 2008;198:184-91. doi:10.1016/j.atherosclerosis.2007.09.025. (Pubitemid 351406371)
33. Nozawa F, Hirota M, Okabe A, Shibata M, Iwamura T, et al. Elastase activity enhances the adhesion of neutrophil and cancer cells to vascular endothelial cells. J Surg Res. 2000;94:153-8. doi:10.1006/jsre.2000.6002.
34. Ruchaud-Sparagano MH, Walker TR, Rossi AG, Haslett C, Dransfield I. Soluble E-selectin acts in synergy with plateletactivating factor to activate neutrophil beta 2-integrins. Role of tyrosine kinases and Ca2+ mobilization. J Biol Chem. 2000;275:15758-64. doi:10.1074/jbc.M907390199. (Pubitemid 30366874)
35. Kumar P, Hosaka S, Koch AE. Soluble E-selectin induces monocyte chemotaxis through Src family tyrosine kinases. J Biol Chem. 2001;276:21039-45. doi:10.1074/jbc.M009099200.
36. Ulich TR, Howard SC, Remick DG, Yi ES, Collins T, et al. Intratracheal administration of endotoxin and cytokines: VIII. LPS induces E-selectin expression; anti-E-selectin and soluble E-selectin inhibit acute inflammation. Inflammation. 1994;18:389-98. (Pubitemid 24268123)
37. Sung BH, Kim SH, Yeo MG, Kim J-K, Song WK. Human soluble E-selectin immunoadhesin inhibits leukemic monocyte adhesion to endothelial cells. Cell Biochem Funct. 2007;25:585-9. doi:10.1002/cbf.1361. (Pubitemid 47436101)
38. Kelemen Z, Moldovan D, Mihály E, Visy B, Széplaki G, et al. Baseline level of functional C1-inhibitor correlates with disease severity scores in hereditary angioedema. Clin Immunol. 2010;134:354-8. doi:10.1016/j.clim.2009.11.002.