Stereological analysis of neuron, glial and endothelial cell numbers in the human amygdaloid complex

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  García Amado, María ^a   Prensa, Lucía ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGE; AGED; AGING; AMYGDALOID NUCLEUS; ANXIETY; ARTICLE; BASOLATERAL AMYGDALA; BRAIN FUNCTION; CELL COUNT; CELL DENSITY; CELL VOLUME; CENTRAL NUCLEUS (AMYGDALA); CORTICAL AMYGDALA; DEATH; ENDOTHELIUM CELL; GLIA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MEDIAL AMYGDALA; MENTAL DISEASE; NERVE CELL; NEUROLOGIC DISEASE; NISSL STAINING; REFERENCE VALUE; STEREOLOGY;

ACETYLCHOLINESTERASE; ADULT; AGED; AMYGDALA; ENDOTHELIUM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEUROGLIA; NEURONS; REFERENCE VALUES;

EID: 84862239905     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038692     Document Type: Article

References (58)

1. Schumann CM, Amaral DG, (2005) Stereological estimation of the number of neurons in the human amygdaloid complex. J Comp Neurol 491 (4): 320-329.
2. Berretta S, Pantazopoulos H, Lange N, (2007) Neuron numbers and volume of the amygdala in subjects diagnosed with bipolar disorder or schizophrenia. Biol Psychiatry 62 (8): 884-893.
3. Bezchlibnyk YB, Sun X, Wang JF, MacQueen GM, McEwen BS, et al. (2007) Neuron somal size is decreased in the lateral amygdalar nucleus of subjects with bipolar disorder. J Psychiatry Neurosci 32 (3): 203-210.
4. Bowley MP, Drevets WC, Ongur D, Price JL, (2002) Low glial numbers in the amygdala in major depressive disorder. Biol Psychiatry 52 (5): 404-412.
5. Kreczmanski P, Heinsen H, Mantua V, Woltersdorf F, Masson T, et al. (2007) Volume, neuron density and total neuron number in five subcortical regions in schizophrenia. Brain 130 (Pt 3): 678-692.
6. Pakkenberg B, (1990) Pronounced reduction of total neuron number in mediodorsal thalamic nucleus and nucleus accumbens in schizophrenics. Arch Gen Psychiatry 47 (11): 1023-1028.
7. Schumann CM, Amaral DG, (2006) Stereological analysis of amygdala neuron number in autism. J Neurosci 26 (29): 7674-7679.
8. Hamidi M, Drevets WC, Price JL, (2004) Glial reduction in amygdala in major depressive disorder is due to oligodendrocytes. Biol Psychiatry 55 (6): 563-569.
9. Kreczmanski P, Heinsen H, Mantua V, Woltersdorf F, Masson T, et al. (2009) Microvessel length density, total length, and length per neuron in five subcortical regions in schizophrenia. Acta Neuropathol 117 (4): 409-421.
10. St Jacques P, Dolcos F, Cabeza R, (2009) Effects of aging on functional connectivity of the amygdala during negative evaluation: a network analysis of fMRI data. Neurobiol Aging 31 (2): 315-327.
11. Pakkenberg B, Gundersen HJ, (1997) Neocortical neuron number in humans: effect of sex and age. J Comp Neurol 384 (2): 312-320.
12. Rubinow MJ, Drogos LL, Juraska JM, (2009a) Age-related dendritic hypertrophy and sexual dimorphism in rat basolateral amygdala. Neurobiol Aging 30 (1): 137-146.
13. Rubinow MJ, Hagerbaumer DA, Juraska JM, (2009b) The food-conditioned place preference task in adolescent, adult and aged rats of both sexes. Behav Brain Res 198 (1): 263-266.
14. Rubinow MJ, Juraska JM, (2009) Neuron and glia numbers in the basolateral nucleus of the amygdala from preweaning through old age in male and female rats: a stereological study. J Comp Neurol 512 (6): 717-725.
15. Nissl F, (1913) Die Grosshirnanteile des Kaninchens. Arch Psychiatr Nervenkr (52): 867-953.
16. Karnovsky MJ, Roots L, (1964) A "Direct-Coloring" Thiocholine Method for Cholinesterases. J Histochem Cytochem 12: 219-221.
17. Gallyas F, (1979) Silver staining of myelin by means of physical development. Neurol Res 1 (2): 203-209.
18. Prensa L, Richard S, Parent A, (2003) Chemical anatomy of the human ventral striatum and adjacent basal forebrain structures. J Comp Neurol 460 (3): 345-367.
19. Uroz V, Prensa L, Gimenez-Amaya JM, (2004) Chemical anatomy of the human paraventricular thalamic nucleus. Synapse 51 (3): 173-185.
20. Konopaske GT, Dorph-Petersen KA, Pierri JN, Wu Q, Sampson AR, et al. (2007) Effect of chronic exposure to antipsychotic medication on cell numbers in the parietal cortex of macaque monkeys. Neuropsychopharmacology 32 (6): 1216-1223.
21. Dorph-Petersen KA, Nyengaard JR, Gundersen HJ, (2001) Tissue shrinkage and unbiased stereological estimation of particle number and size. J Microsc 204 (Pt 3): 232-246.
22. Hatton WJ, von Bartheld CS, (1999) Analysis of cell death in the trochlear nucleus of the chick embryo: calibration of the optical disector counting method reveals systematic bias. J Comp Neurol 409 (2): 169-186.
23. Schmitz C, Korr H, Perl DP, Hof PR, (2001) Advanced use of 3-D methods for counting neurons. Trends Neurosci 24 (7): 377-380.
24. Sims KS, Williams RS, (1990) The human amygdaloid complex: a cytologic and histochemical atlas using Nissl, myelin, acetylcholinesterase and nicotinamide adenine dinucleotide phosphate diaphorase staining. Neuroscience 36 (2): 449-472.
25. Sorvari H, Soininen H, Paljarvi L, Karkola K, Pitkanen A, (1995) Distribution of parvalbumin-immunoreactive cells and fibers in the human amygdaloid complex. J Comp Neurol 360 (2): 185-212.
26. Mai JK, Assheuer J, Paxinos G, (2004) Atlas of the Human Brain. Second edn. Elsevier Academic Press, San Diego, California.
27. Gundersen HJ, Jensen EB, (1987) The efficiency of systematic sampling in stereology and its prediction. J Microsc 147 (Pt 3): 229-263.
28. West MJ, Gundersen HJ, (1990) Unbiased stereological estimation of the number of neurons in the human hippocampus. J Comp Neurol 296 (1): 1-22.
29. Sterio DC, (1984) The unbiased estimation of number and sizes of arbitrary particles using the disector. J Microsc 134 (Pt 2): 127-136.
30. Bermejo PE, Jimenez CE, Torres CV, Avendano C, (2003) Quantitative stereological evaluation of the gracile and cuneate nuclei and their projection neurons in the rat. J Comp Neurol 463 (4): 419-433.
31. Gundersen HJ, Jensen EB, Kieu K, Nielsen J, (1999) The efficiency of systematic sampling in stereology-reconsidered. J Microsc 193 (Pt 3): 199-211.
32. Haug H, Kuhl S, Mecke E, Sass NL, Wasner K, (1984) The significance of morphometric procedures in the investigation of age changes in cytoarchitectonic structures of human brain. J Hirnforsch 25 (4): 353-374.
33. Boonstra H, Oosterhuis JW, Oosterhuis AM, Fleuren GJ, (1983) Cervical tissue shrinkage by formaldehyde fixation, paraffin wax embedding, section cutting and mounting. Virchows Arch A Pathol Anat Histopathol 402 (2): 195-201.
34. Gardella D, Hatton WJ, Rind HB, Rosen GD, von Bartheld CS, (2003) Differential tissue shrinkage and compression in the z-axis: implications for optical disector counting in vibratome-, plastic- and cryosections. J Neurosci Methods 124 (1): 45-59.
35. Andersen BB, Gundersen HJ, (1999) Pronounced loss of cell nuclei and anisotropic deformation of thick sections. J Microsc 196 (Pt 1): 69-73.
36. Dorph-Petersen KA, Caric D, Saghafi R, Zhang W, Sampson AR, et al. (2008) Volume and neuron number of the lateral geniculate nucleus in schizophrenia and mood disorders. Acta Neuropathol 117 (4): 369-384.
37. Boyce RW, Dorph-Petersen KA, Lyck L, Gundersen HJ, (2010) Design-based stereology: introduction to basic concepts and practical approaches for estimation of cell number. Toxicol Pathol 38 (7): 1011-1025.
38. Stan AD, Ghose S, Gao XM, Roberts RC, Lewis-Amezcua K, et al. (2006) Human postmortem tissue: what quality markers matter? Brain Res 1123 (1): 1-11.
39. Chance SA, Esiri MM, Crow TJ, (2002) Amygdala volume in schizophrenia: post-mortem study and review of magnetic resonance imaging findings. Br J Psychiatry 180: 331-338.
40. Heckers S, Heinsen H, Heinsen YC, Beckmann H, (1990) Limbic structures and lateral ventricle in schizophrenia. A quantitative postmortem study. Arch Gen Psychiatry 47 (11): 1016-1022.
41. Hajek T, Kopecek M, Kozeny J, Gunde E, Alda M, et al. (2008) Amygdala volumes in mood disorders-meta-analysis of magnetic resonance volumetry studies. J Affect Disord 115 (3): 395-410.
42. Decampo DM, Fudge JL, (2012) Where and what is the paralaminar nucleus? A review on a unique and frequently overlooked area of the primate amygdala. Neurosci Biobehav Rev 36: 520-535.
43. Yachnis AT, Roper SN, Love A, Fancey JT, Muir D, (2000) Bcl-2 immunoreactive cells with immature neuronal phenotype exist in the nonepileptic adult human brain. J Neuropathol Exp Neurol 59 (2): 113-119.
44. Zhang X-M, Cai Y, Chu Y, Chen E-Y, Feng J-C, et al. (2009) Doublecortin-expressing cells persist in the associative cerebral cortex and amygdala in aged nonhuman primates. Frontiers in Neuroanatomy 3: 17. doi 10.3389/neuro.05.017.2009.
45. Carlo CN, Stefanacci L, Semendeferi K, Stevens CF, (2010) Comparative analyses of the neuron numbers and volumes of the amygdaloid complex in old and new world primates. J Comp Neurol 518 (8): 1176-1198.
46. Price JL, (2003) Comparative aspects of amygdala connectivity. Ann N Y Acad Sci 985: 50-58.
47. Sherwood CC, Stimpson CD, Raghanti MA, Wildman DE, Uddin M, et al. (2006) Evolution of increased glia-neuron ratios in the human frontal cortex. PNAS 37 (3): 13606-13611.
48. Kaye JA, Swihart T, Howieson D, Dame A, Moore MM, et al. (1997) Volume loss of the hippocampus and temporal lobe in healthy elderly persons destined to develop dementia. Neurology 48 (5): 1297-1304.
49. Lehericy S, Baulac M, Chiras J, Pierot L, Martin N, et al. (1994) Amygdalohippocampal MR volume measurements in the early stages of Alzheimer disease. AJNR Am J Neuroradiol 15 (5): 929-937.
50. Grieve SM, Korgaonkar MS, Clark CR, Williams LM, (2011) Regional heterogeneity in limbic maturational changes: Evidence from integrating cortical thickness, volumetric and diffusion tensor imaging measures. Neuroimage 55(3): 868-79.
51. Mu Q, Xie J, Wen Z, Weng Y, Shuyun Z, (1999) A quantitative MR study of the hippocampal formation, the amygdala, and the temporal horn of the lateral ventricle in healthy subjects 40 to 90 years of age. AJNR Am J Neuroradiol 20 (2): 207-211.
52. Beach TG, Walker R, McGeer EG, (1989) Patterns of gliosis in Alzheimer's disease and aging cerebrum. Glia 2 (6): 420-436.
53. Burzynska AZ, Preuschhof C, Backman L, Nyberg L, Li SC, et al. (2010) Age-related differences in white matter microstructure: region-specific patterns of diffusivity. Neuroimage 49 (3): 2104-2112.
54. Kushner PD, Stephenson DT, Wright S, (1991) Reactive astrogliosis is widespread in the subcortical white matter of amyotrophic lateral sclerosis brain. J Neuropathol Exp Neurol 50 (3): 263-277.
55. Middeldorp J, Hol EM, (2011) GFAP in health and disease. Prog Neurobiol 93(3): 421-43.
56. Muramori F, Kobayashi K, Nakamura I, (1998) A quantitative study of neurofibrillary tangles, senile plaques and astrocytes in the hippocampal subdivisions and entorhinal cortex in Alzheimer's disease, normal controls and non-Alzheimer neuropsychiatric diseases. Psychiatry Clin Neurosci 52 (6): 593-599.
57. Asllani I, Habeck C, Borogovac A, Brown TR, Brickman AM, et al. (2009) Separating function from structure in perfusion imaging of the aging brain. Hum Brain Mapp 30 (9): 2927-2935.
58. LaManna JC, Chavez JC, Pichiule P, (2004) Structural and functional adaptation to hypoxia in the rat brain. J Exp Biol 207 (Pt 18): 3163-3169.