Design and realisation of tissue-equivalent dielectric simulators for dosimetric studies on microwave antennas for interstitial ablation

Physica Medica

Volumn 28, Issue 3, 2012, Pages 245-253

  Lopresto, V ^a   Pinto, R ^a   Lodato, R ^a   Lovisolo, G A ^a   Cavagnaro, M ^b  

^a ENEA C R CASACCIA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Dielectric simulators; Interstitial antennas; Microwave ablation; Tissue equivalent material

Indexed keywords

ABLATION THERAPY; ARTICLE; DIELECTRIC SIMULATOR; DOSIMETRY; INTERSTITIAL ABLATION; KIDNEY PARENCHYMA; LIQUID; LIVER; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MEASUREMENT; MICROWAVE THERAPY; PHANTOM; POSITION; RADIOFREQUENCY; SIMULATION; SIMULATOR; TREATMENT PLANNING; VALIDATION STUDY;

ABLATION TECHNIQUES; ELECTRIC IMPEDANCE; HUMANS; KIDNEY; LIVER; MICROWAVES; PHANTOMS, IMAGING; RADIOMETRY; REPRODUCIBILITY OF RESULTS;

EID: 84862238887     PISSN: 11201797     EISSN: 1724191X     Source Type: Journal    
DOI: 10.1016/j.ejmp.2011.09.001     Document Type: Article

References (35)

1. Diederich C.J. Thermal ablation and high-temperature thermal therapy: overview of technology and clinical implementation. Int J Hyperthermia 2005, 21(8):745-753.
2. Haemmerich D., Laeseke P.F. Thermal tumour ablation: devices, clinical applications and future directions. Int J Hyperthermia 2005, 21(8):755-760.
3. Ryan T.P., Turner P.F., Hamilton B. Interstitial microwave transition from hyperthermia to ablation: historical perspectives and current trends in thermal therapy. Int J Hyperthermia 2010, 26(5):415-433.
4. Sato M., Watanabe Y., Ueda S., Iseki S., Abe Y., Sato N., et al. Microwave coagulation therapy for Hepatocellular Carcinoma. Gastroenterology 1996, 110:1507-1514.
5. Martin R.C.G., Scoggins C.R., McMasters K.M. Safety and efficacy of microwave ablation of hepatic tumors: a prospective review of a 5-year experience. Ann Surg Oncol 2010, 17:171-178.
6. Brace C.L., Laeseke P.F., van der Weide D.W., Lee F.T. Microwave ablation with a triaxial antenna: results in ex vivo Bovine liver. IEEE Trans Microw Theory Techn 2005, 53(1):215-220.
7. Bertram J.M., Yang D., Converse M.C., Webster J.G., Mahvi D.M. A review of coaxial-based interstitial antennas for hepatic microwave ablation. Crit Rev Biomed Eng 2006, 34(3):187-213.
8. Yeh M.M., Trembly S., Douple E.B., Ryan T.P., Hoopes P.J., Jonsson E., et al. Theoretical and experimental analysis of air cooling for intracavitary microwave hyperthermia applicators. IEEE Trans Biomed Eng 1994, 41(9):874-882.
9. Wright A.S., Lee F.T., Mahvi D.M. Hepatic microwave ablation with multiple antennae results in synergistically larger zones of coagulation necrosis. Ann Surg Oncol 2002, 10(3):275-283.
10. Federal Communications Commission (FCC) Office of Engineering & Technology (OET). Evaluating compliance with FCC guidelines for human exposure to radiofrequency electromagnetic fields - Additional information for evaluating compliance of mobile and portable devices with FCC limits for human exposure to radiofrequency emissions. Supplement C (Ed. 01-01) to OET Bulletin 65 (Ed. 97-01), 2001.
11. Institute of Electrical and Electronic Engineers (IEEE). Recommended Practice for determining the peak spatial-average specific absorption rate (SAR) in the human head from wireless communications devices: measurement techniques. IEEE Stand 1528, 2003.
12. European Committee for Electrotechnical Standardization (CENELEC). Human exposure to radio frequency fields from hand-held and body-mounted wireless communication devices - Human models, instrumentation, and procedures - part 2: procedure to determine the specific absorption rate (SAR) for mobile wireless communication devices used in close proximity to the human body (frequency range of 30 MHz to 6 GHz). IEC Standard 62209 ed. 1.0, 2010.
13. Guy W. Analyses of electromagnetic fields induced in biological tissues by thermographic studies on equivalent phantom models. IEEE Trans Microw Theory Techn 1971, 19(2):205-214.
14. Lovisolo G.A., Pinto R., Ardoino L., Mancini S. Dosimetric techniques for the evaluation of the em power absorption induced by cellular phones. Radiat Prot Dosim 2001, 97(4):369-374.
15. Leonard J.B., Foster K.R., Athey T.W. Thermal properties of tissue equivalent phantom materials. IEEE Trans Biomed Eng 1984, 31(7):533-536.
16. Ito K., Furuya K., Okano Y., Hamada L. Development and characteristics of a biological tissue-equivalent phantom for microwaves. Electronics Commun Jpn Part 1 2001, 84(4):67-77.
17. Kato H., Ishida T. Development of an agar phantom adaptable for simulation of various tissues in the range 5-40 MHz. Phys Med Biol 1987, 32(2):221-226.
18. Robinson M.P., Richardson M.J., Greent J.L., Preece A.W. New materials for dielectric simulation of tissues. Phys Med Biol 1991, 36(12):1565-1571.
19. Chou C.K., Chen G.W., Guy A.W., Luk K.H. Formulas for preparing phantom muscle tissue at various radiofrequenciesm. Bioelectromagnetics 1984, 5:435-441.
20. Bini M., Ignesti A., Millanta L., Olmi R., Rubino N., Vanni R. The polyacrylamide as a phantom material for electromagnetic hyperthermia studies. IEEE Trans Biomed Eng 1984, 31:317-322.
21. Andreuccetti D., Bini M., Ignesti A., Olmi R., Rubino N., Vanni R. Use of polyacrylamide as a tissue-equivalent material in the microwave range. IEEE Trans Biomed Eng 1988, 35(4):275-277.
22. Fukunaga K., Watanabe K.S., Yamanaka Y. Dielectric properties of tissue-equivalent liquids and their Effects on specific absorption rate. IEEE Trans Biomed Eng 2004, 46(1):126-129.
23. Hartsgrove G., Kraszewski A., Surowiec A. Simulated biological materials for electromagnetic radiation absorption studies. Bioelectromagnetics 1987, 8:29-36.
24. Kanda M.Y., Ballen M., Salins S., Chou C.K., Balzano Q. Formulation and characterisation of tissue equivalent liquids used for RF densitometry and dosimetry measurements. IEEE Trans Microw Theory Techn 2004, 52(8):2046-2056.
25. Stauffer P.R., Rossetto F., Prakash M., Neuman D.G., Lee T. Phantom and animal tissues for modelling the electrical properties of human liver. Int J Hyperthermia 2003, 19(1):89-101.
26. Prakash P., Converse M.C., Mahvi D.M., Webster J.G. Measurement of the specific heat capacity of liver phantom. Physiol Meas 2006, 27:41-46.
27. Fukunaga K., Watanabe S., Asou H., Sato K. Dielectric properties of non-toxic tissue-equivalent liquids for radiowave safety tests. IEEE Int Conf Dielectric Liquids 2005, 26:425-428.
28. Gabriel C. Compilation of the dielectric properties of body tissues at RF and microwave frequencies 1996, U.S. Air Force, Report AFOSR-TR-96. Available on-line at:, or at:. http://niremf.ifac.cnr.it/tissprop/.
29. User's Manual: HP 85070B dielectric probe kit. Hewlett-Packard 85070-90009, Santa Rosa, April 1993.
30. Taflove A., Hagness S.C. Computational Electrodynamics: the finite-difference time-domain method 2000, Artech House, Boston.
31. Bernardi P., Cavagnaro M., Lin J.C., Pisa S., Piuzzi E. Distribution of SAR and temperature elevation induced in a phantom by a microwave cardiac ablation catheter. IEEE Trans Microw Theory Techn 2004, 52(8):1978-1986. SI.
32. Cavagnaro M., Amabile C., Bernardi P., Pisa S., Tosoratti N. A minimally invasive antenna for microwave ablation therapies: design, performances, and experimental assessment. IEEE Trans Biomed Eng 2011, 58(4):949-959.
33. Longo I. C.N.R. Industrial Patent N. PI/2001/A/000 006 2001.
34. Lazebnik M., Converse M.C., Booske J.H., Hagness S.C. Ultrawideband temperature-dependent dielectric properties of animal liver tissue in the microwave frequency range. Phys Med Biol 2006, 51:1941-1955.
35. O'Rourke A.P., Lazebnik M., Bertram J.M., Converse M.C., Hagness S.C., Webster J.G., et al. Dielectric properties of human normal, malignant and cirrhotic liver tissue: in vivo and ex vivo measurements from 0.5 to 20 GHz using a precision open-ended coaxial probe. Phys Med Biol 2007, 52:4707-4719.