Outcomes of transplantation using organs from a donor infected with Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae

Transplant Infectious Disease

Volumn 14, Issue 3, 2012, Pages 229-236

  Ariza Heredia, E J ^a   Patel, R ^a   Blumberg, E A ^b   Walker, R C ^a   Lewis, R ^c   Evans, J ^c   Sankar, A ^c   Willliams, M D ^d   Rogers, J ^d   Milano, C ^d   Razonable, R R ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c North Austin Medical Center   (United States)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Adverse effects; Carbapenem resistance; Klebsiella pneumoniae; KPC; Solid organ transplant; Transmission

Indexed keywords

ALEMTUZUMAB; AMIKACIN; AMPHOTERICIN B; AMPICILLIN; BASILIXIMAB; CARBAPENEMASE; CEFEPIME; CEFTAZIDIME; CIPROFLOXACIN; COLISTIN; COTRIMOXAZOLE; CYCLOSPORIN A; FLUCONAZOLE; GENTAMICIN; MEROPENEM; METHYLPREDNISOLONE; MICAFUNGIN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS; TIGECYCLINE; VALACICLOVIR; VALGANCICLOVIR; VANCOMYCIN;

ABDOMINAL PAIN; ABDOMINAL TENDERNESS; ACUTE GRAFT REJECTION; ACUTE KIDNEY TUBULE NECROSIS; ADD ON THERAPY; ADULT; ALCOHOL LIVER CIRRHOSIS; ALPHA 1 ANTITRYPSIN DEFICIENCY; ANTIBIOTIC PROPHYLAXIS; ARTICLE; BILE DUCT CARCINOMA; BLOOD CULTURE; CANDIDIASIS; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; CYTOMEGALOVIRUS INFECTION; DISEASE COURSE; DRUG POTENTIATION; GRAFT RECIPIENT; HEART TRANSPLANTATION; HEMODIALYSIS; HUMAN; KIDNEY TRANSPLANTATION; KLEBSIELLA PNEUMONIAE; KLEBSIELLA PNEUMONIAE INFECTION; LAPAROTOMY; LEUKOCYTOSIS; LIVER HEMATOMA; LIVER TRANSPLANTATION; LIVING DONOR; LOADING DRUG DOSE; MALE; MENINGITIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; ORGAN TRANSPLANTATION; PERCUTANEOUS DRAINAGE; PERITONITIS; PNEUMONIA; PRIMARY SCLEROSING CHOLANGITIS; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; SUBDURAL HEMATOMA; TREATMENT OUTCOME; VEIN GRAFT;

AGED; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAMASES; DRUG RESISTANCE, MULTIPLE, BACTERIAL; DRUG THERAPY, COMBINATION; HEART TRANSPLANTATION; HEMATOMA; HUMANS; KIDNEY TRANSPLANTATION; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; LIVER TRANSPLANTATION; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; ORGAN PRESERVATION SOLUTIONS; PERITONITIS; TISSUE AND ORGAN HARVESTING; TISSUE DONORS; YOUNG ADULT;

EID: 84862217972     PISSN: 13982273     EISSN: 13993062     Source Type: Journal    
DOI: 10.1111/j.1399-3062.2012.00742.x     Document Type: Article

References (26)

1. Ison MG, Nalesnik MA. An update on donor-derived disease transmission in organ transplantation. Am J Transplant 2011; 11 (6): 1123-1130.
2. Johnston L, Chui L, Chang N, et al. Cross-Canada spread of methicillin-resistant Staphylococcus aureus via transplant organs. Clin Infect Dis 1999; 29 (4): 819-823.
3. Nelson PW, Delmonico FL, Tolkoff-Rubin NE, et al. Unsuspected donor Pseudomonas infection causing arterial disruption after renal transplantation. Transplantation 1984; 37 (3): 313-314.
4. Grossi PA. Clinical aspects of invasive candidiasis in solid organ transplant recipients. Drugs 2009; 69 (Suppl 1): 15-20.
5. Little DM, Farrell JG, Cunningham PM, Hickey DP. Donor sepsis is not a contraindication to cadaveric organ donation. QJM 1997; 90 (10): 641-642.
6. Kubak BM, Gregson AL, Pegues DA, et al. Use of hearts transplanted from donors with severe sepsis and infectious deaths. J Heart Lung Transplant 2009; 28 (3): 260-265.
7. Freeman RB, Giatras I, Falagas ME, et al. Outcome of transplantation of organs procured from bacteremic donors. Transplantation 1999; 68 (8): 1107-1111.
8. Hirsch EB, Tam VH. Detection and treatment options for Klebsiella pneumoniae carbapenemases (KPCs): an emerging cause of multidrug-resistant infection. J Antimicrob Chemother 2010; 65 (6): 1119-1125.
9. Mathers AJ, Cox HL, Bonatti H, et al. Fatal cross infection by carbapenem-resistant Klebsiella in two liver transplant recipients. Transpl Infect Dis 2009; 11 (3): 257-265.
10. TM Assay for the Rapid Detection of KPC Producing Enterobacteriaceae from Cultured Isolates. Infectious Diseases Society of America Annual Meeting, Washington, DC, October 2008.
11. Doig RL, Boyd PJ, Eykyn S. Staphylococcus aureus transmitted in transplanted kidneys. Lancet 1975; 2 (7928): 243-245.
12. Nery JR, Weppler D, Ketchum P, et al. Donor infection and primary nonfunction in liver transplantation. Transplant Proc 1997; 29 (1-2): 481-483.
13. Fischer SA, Graham MB, Kuehnert MJ, et al. Transmission of lymphocytic choriomeningitis virus by organ transplantation. N Engl J Med 2006; 354 (21): 2235-2249.
14. Bronnert J, Wilde H, Tepsumethanon V, Lumlertdacha B, Hemachudha T. Organ transplantations and rabies transmission. J Travel Med 2007; 14 (3): 177-180.
15. Centers for Disease Control and Prevention (CDC). Balamuthia mandrillaris transmitted through organ transplantation - Mississippi, 2009. MMWR Morb Mortal Wkly Rep 2010; 59 (36): 1165-1170.
16. Rhee C, Eaton EF, Concepcion W, Blackburn BG. West Nile virus encephalitis acquired via liver transplantation and clinical response to intravenous immunoglobulin: case report and review of the literature. Transpl Infect Dis 2011; 13 (3): 312-317.
17. Ison MG, Llata E, Conover CS, et al. Transmission of human immunodeficiency virus and hepatitis C virus from an organ donor to four transplant recipients. Am J Transplant 2011; 11 (6): 1218-1225.
18. Centers for Disease Control and Prevention (CDC). Transmission of multidrug-resistant Escherichia coli through kidney transplantation - California and Texas, 2009. MMWR Morb Mortal Wkly Rep 2010; 59 (50): 1642-1646.
19. Mai H, Champion L, Ouali N, et al. Candida albicans arteritis transmitted by conservative liquid after renal transplantation: a report of four cases and review of the literature. Transplantation 2006; 82 (9): 1163-1167.
20. Albano L, Bretagne S, Mamzer-Bruneel MF, et al. Evidence that graft-site candidiasis after kidney transplantation is acquired during organ recovery: a multicenter study in France. Clin Infect Dis 2009; 48 (2): 194-202.
21. Tascini C, Urbani L, Biancofiore G, et al. Colistin in combination with rifampin and imipenem for treating a blaVIM-1 metallo-beta-lactamase-producing Enterobacter cloacae disseminated infection in a liver transplant patient. Minerva Anestesiol 2008; 74 (1-2): 47-49.
22. Rasheed J, Newton D. Detection of the Klebsiella pneumoniae carbapenemase type 2 carbapenem-hydrolyzing enzyme in clinical isolates of Citrobacter freundii and K. oxytoca carrying a common plasmid. J Clin Microbiol 2008; 46 (6): 2066-2069.
23. Anthony KB, Fishman NO, Linkin DR, Gasink LB, Edelstein PH, Lautenbach E. Clinical and microbiological outcomes of serious infections with multidrug-resistant gram-negative organisms treated with tigecycline. Clin Infect Dis 2008; 46 (4): 567-570.
24. Al Qadheeb NS, Althawadi S, Alkhalaf A, Hosaini S, Alrajhi AA. Evolution of tigecycline resistance in Klebsiella pneumoniae in a single patient. Ann Saudi Med 2010; 30 (5): 404-407.
25. De Soyza A, Meachery G, Hester KL, et al. Lung transplantation for patients with cystic fibrosis and Burkholderia cepacia complex infection: a single-center experience. J Heart Lung Transplant 2010; 29 (12): 1395-1404.
26. Centers for Disease Control and Prevention (CDC). Guidance for control of infections with carbapenem-resistant or carbapenemase-producing Enterobacteriaceae in acute care facilities. MMWR Morb Mortal Wkly Rep 2009; 58 (10); 256-260.