Discovering associative long-term synaptic modification and timing dependence of plasticity - A very brief and personal history

Frontiers in Synaptic Neuroscience

Volumn , Issue DEC, 2010, Pages

  Levy, William B ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COGNITION; DENTATE GYRUS; ENTORHINAL CORTEX; HIPPOCAMPAL CA1 REGION; LONG TERM DEPRESSION; LONG TERM POTENTIATION; NERVE CELL PLASTICITY; SPIKE TIMING DEPENDENT PLASTICITY;

EID: 84862206628     PISSN: None     EISSN: 16633563     Source Type: Journal    
DOI: 10.3389/fnsyn.2010.00149     Document Type: Article

References (15)

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2. Bliss, T. V. P., and Lømo, T. (1973). Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J. Physiol. 232, 331-356.
3. Desmond, N. L., Colbert, C. M., Zhang, D. X., and Levy, W. B. (1991). NMDA receptor antagonists block the induction of long-term depression in the hippocampal dentate gyrus of the anesthetized rat. Brain Res. 552, 93-98.
4. Gustafsson, B., Wigström, H., Abraham, W. C., and Huang, Y.-Y. (1987). Long-term potentiation in the hippocampus using depolarizing current pulses as the conditioning stimulus to single volley synaptic potentials. J. Neurosci. 7, 774-780.
5. Holmes, W. R., and Levy, W. B. (1990). Insights into associative long-term potentiation from computational models of NMDA receptor-mediated calcium influx and intracellular calcium concentration changes. J. Neurophysiol. 63, 1148-1168.
6. Levy, W. B. (1985). "Associative changes at the synapse: LTP in the hippocampus," in Synaptic Modification, Neuron Selectivity and Nervous System Organization, eds W. B Levy, J. Anderson, and S. Lehmkuhle (Hillsdale, NJ: Lawrence Erlbaum Assoc., Inc.), 5-33.
7. Levy, W. B. (1989). "A computational approach to hippocampal function," in Computational Models of Learning in Simple Neural Systems, eds R. D. Hawkins and G. H. Bower (New York: Academic Press), 243-305.
8. Levy, W. B., Colbert, C. M., and Desmond, N. L. (1990). "Elemental adaptive processes of neurons and synapses: a statistical/computational perspective," in: Neuroscience and Connectionist Models, eds M. A. Gluck and D. E. Rumelhart (Hillsdale, NJ: Lawrence Erlbaum Assoc., Inc.), 187-235.
9. Levy, W. B., and Desmond, N. L. (1985). "The rules of elemental synaptic plasticity," in Synaptic Modification, Neuron Selectivity and Nervous System Organization, eds W. B Levy, J. Anderson, and S. Lehmkuhle (Hillsdale, NJ: Lawrence Erlbaum Assoc., Inc.), 105-121.
10. Levy, W. B., and Steward, O. (1979). Synapses as associative memory elements in the hippocampal formation. Brain Res. 175, 233-245.
11. Levy, W. B., and Steward, O. (1983). Temporal contiguity requirements for long-term associative potentiation/depression in the hippocampus. Neuroscience 8, 791-797.
12. Lopez, H. S., Burger, B., Dickstein, R., Desmond, N. L., and Levy, W. B. (1990). Associative synaptic potentiation and depression: quantification of dissociable modifications in the hippocampal dentate gyrus favors a particular class of synaptic modification equations. Synapse 5, 33-47.
13. McNaughton, B. L. (1977). Dissociation of short-and long-lasting modification of synaptic efficacy at the terminals of the perforant path. Seventh Annual Meeting of the Society for Neuroscience, Anaheim, CA, Abstract.
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15. White, G., Levy, W. B., and Steward, O. (1990). Spatial overlap between populations of synapses determines the extent of their associative interaction during the induction of long term potentiation and depression. J. Neurophysiol. 64, 1186-1198.