Multiple birthdating analyses in adult neurogenesis: A line-up of the usual suspects

Frontiers in Neuroscience

Volumn , Issue MAY, 2011, Pages 1-8

  Llorens Martín, María ^a   Trejo, José L ^a  

^a INSTITUTO CAJAL   (Spain)

Author keywords

BrdU; CldU; Dentate gyrus; Dual birthdating; IdU; Neurogenesis

Indexed keywords

BROXURIDINE; CELL MARKER; THYMIDINE DERIVATIVE;

BRAIN NERVE CELL; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL LABELING; CELL SUBPOPULATION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; NERVE CELL STIMULATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEUROBLAST; NEUROPHYSIOLOGY; REVIEW; SENSITIVITY AND SPECIFICITY;

EID: 84862183647     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2011.00076     Document Type: Review

References (34)

1. Aimone, J. B., Deng, W., and Gage, F. H. (2010). Adult neurogenesis: integrat-ing theories and separating func-tions. Trends Cogn. Sci. (Regul. Ed.) 14, 325-337.
2. Aten, J. A., Bakker, P. J., Stap, J., Boschman, G. A., and Veenhof, C. H. (1992). DNA dual labelling with IdUrd and CldUrd for spatial and temporal analysis of cell proliferation and DNA replication. Histochem. J. 24, 251-259.
3. Bakker, P. J., Stap, J., Tukker, C. J., van Oven, C. H., Veenhof, C. H., and Aten, J. (1991). An indirect immuno-fluorescence dual staining procedure for the simultaneous flow cytometric measurement of iodo- and chlorode-oxyuridine incorporated into DNA. Cytometry 12, 366-372.
4. Bauer, S., and Patterson, P. H. (2005). The cell cycle-apoptosis connection revis-ited in the adult brain. J. Cell Biol. 171, 641-650.
5. Bauer, S., and Patterson, P. H. (2006). Leukemia inhibitory factor pro-motes neural stem cell self-renewal in the adult brain. J. Neurosci. 26, 12089-12099.
6. Bonaguidi, M. A., Peng, C. Y., McGuire, T., Falciglia, G., Gobeske, K. T., Czeisler, C., and Kessler, J. A. (2008). Noggin expands neural stem cells in the adult hippocampus. J. Neurosci. 28, 9194-9204.
7. Bradford, J. A., and Clarke, S. T. (2011). Dual-pulse labeling using 5-ethynyl- 2'-deoxyuridine (EdU) and 5-bromo- 2'-deoxyuridine (BrdU) in flow cytometry. Curr. Protoc. Cytom. Chapter 7, Unit7 38, PMID 21207361.
8. Brandt, M. D., Maass, A., Kempermann, G., and Storch, A. (2010). Physical exercise increases Notch activity, pro-liferation and cell cycle exit of type-3 progenitor cells in adult hippocam-pal neurogenesis. Eur. J. Neurosci. 32, 1256-1264.
9. Breunig, J. J., Silbereis, J., Vaccarino, F. M., Sestan, N., and Rakic, P. (2007). Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus. Proc. Natl. Acad. Sci. U.S.A. 104, 20558-20563.
10. Burns, K. A., and Kuan, C. Y. (2005). Low doses of bromo- and iododeoxyu-ridine produce near-saturation labe-ling of adult proliferative populations in the dentate gyrus. Eur. J. Neurosci. 21, 803-807.
11. Burns, T. C., Ortiz-Gonzalez, X. R., Gutierrez-Perez, M., Keene, C. D., Sharda, R., Demorest, Z. L., Jiang, Y., Nelson-Holte, M., Soriano, M., Nakagawa, Y., Luquin, M. R., Garcia- Verdugo, J. M., Prosper, F., Low, W. C., and Verfaillie, C. M. (2006). Thymidine analogues are transferred from prelabeled donor to host cells in the central nervous system after transplantation: a word of caution. Stem Cells 24, 1121-1127.
12. Chehrehasa, F., Meedeniya, A. C., Dwyer, P., Abrahamsen, G., and Mackay-Sim, A. (2009). EdU, a new thymidine ana-logue for labelling proliferating cells in the nervous system. J. Neurosci. Methods 177, 122-130.
13. Deng, W., Aimone, J. B., and Gage, F. H. (2010). New neurons and new memo-ries: how does adult hippocampal neu-rogenesis affect learning and memory? Nat. Rev. Neurosci. 11, 339-350.
14. Dupret, D., Fabre, A., Dobrossy, M. D., Panatier, A., Rodriguez, J. J., Lamarque, S., Lemaire, V., Oliet, S. H., Piazza, P. V., and Abrous, D. N. (2007). Spatial learning depends on both the addition and removal of new hippocampal neu-rons. PLoS Biol. 5, e214. doi: 10.1371/ journal.pbio.0050214
15. Eisch, A. J., and Mandyam, C. D. (2007). Adult neurogenesis: can analysis of cell cycle proteins move us "Beyond BrdU" ? Curr. Pharm. Biotechnol. 8, 147-165.
16. Gobeske, K. T., Das, S., Bonaguidi, M. A., Weiss, C., Radulovic, J., Disterhoft, J. F., and Kessler, J. A. (2009). BMP sign-aling mediates effects of exercise on hippocampal neurogenesis and cogni-tion in mice. PLoS One 4, e7506. doi: 10.1371/journal.pone.0007506
17. Hoshino, T., Ito, S., Asai, A., Shibuya, M., Prados, M. D., Dodson, B. A., Davis, R. L., and Wilson, C. B. (1992). Cell kinetic analysis of human brain tumors by in situ dual labelling with bromodeoxyuridine and iododeoxyu-ridine. Int. J. Cancer 50, 1-5.
18. Kempermann, G. (2006). Adult Neurogenesis. New York: Oxford University Press.
19. Landgren, H., and Curtis, M. A. (2010). Locating and labeling neural stem cells in the brain. J. Cell. Physiol. 226, 1-7.
20. Leuner, B., Glasper, E. R., and Gould, E. (2009). Thymidine analogue methods for studies of adult neurogenesis are not equally sensitive. J. Comp. Neurol. 517, 123-133.
21. Llorens-Martin, M., Tejeda, G. S., and Trejo, J. L. (2010). Differential regu-lation of the variations induced by environmental richness in adult neurogenesis as a function of time: a dual birthdating analysis. PLoS One 5, e12188. doi: 10.1371/journal. pone.0012188
22. Llorens-Martin, M. V., Rueda, N., Martinez- Cue, C., Torres-Aleman, I., Florez, J., and Trejo, J. L. (2007). Both increases in immature dentate neuron number and decreases of immobility time in the forced swim test occurred in parallel after environmental enrichment of mice. Neuroscience 147, 631-638.
23. Lugert, S., Basak, O., Knuckles, P., Haussler, U., Fabel, K., Gotz, M., Haas, C. A., Kempermann, G., Taylor, V., and Giachino, C. (2010). Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and patho-logical stimuli and aging. Cell Stem Cell 6, 445-456.
24. Manders, E. M., Stap, J., Brakenhoff, G. J., van Driel, R., and Aten, J. A. (1992). Dynamics of three-dimensional rep-lication patterns during the S-phase, analysed by dual labelling of DNA and confocal microscopy. J. Cell. Sci. 103, 857-862.
25. Maslov, A. Y., Barone, T. A., Plunkett, R. J., and Pruitt, S. C. (2004). Neural stem cell detection, characterization, and age-related changes in the subven-tricular zone of mice. J. Neurosci. 24, 1726-1733.
26. Mira, H., Andreu, Z., Suh, H., Lie, D. C., Jessberger, S., Consiglio, A., San Emeterio, J., Hortiguela, R., Marques- Torrejon, M. A., Nakashima, K., Colak, D., Gotz, M., Farinas, I., and Gage, F. H. (2010). Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus. Cell Stem Cell 7, 78-89.
27. Shibui, S., Hoshino, T., Vanderlaan, M., and Gray, J. W. (1989). Dual labeling with iodo- and bromodeoxyuridine for cell kinetics studies. J. Histochem. Cytochem. 37, 1007-1011.
28. Stone, S. S., Teixeira, C. M., Zaslavsky, K., Wheeler, A. L., Martinez-Canabal, A., Wang, A. H., Sakaguchi, M., Lozano, A. M., and Frankland, P. W. (2010). Functional convergence of develop-mentally and adult-generated gran-ule cells in dentate gyrus circuits supporting hippocampus-dependent memory. Hippocampus, doi: 10.1002/ hipo.20845. [Epub ahead of print].
29. Thomas, R. M., Hotsenpiller, G., and Peterson, D. A. (2007). Acute psycho-social stress reduces cell survival in adult hippocampal neurogenesis with-out altering proliferation. J. Neurosci. 27, 2734-2743.
30. Tronel, S., Fabre, A., Charrier, V., Oliet, S. H., Gage, F. H., and Abrous, D. N. (2010). Spatial learning sculpts the dendritic arbor of adult-born hip-pocampal neurons. Proc. Natl. Acad. Sci. U.S.A. 107, 7963-7968.
31. Tuttle, A. H., Rankin, M. M., Teta, M., Sartori, D. J., Stein, G. M., Kim, G. J., Virgilio, C., Granger, A., Zhou, D., Long, S. H., Schiffman, A. B., and Kushner, J. A. (2010). Immunofluorescent detec-tion of two thymidine analogueues (CldU and IdU) in primary tissue. J. Vis. Exp. 46, 2166.
32. Vega, C. J., and Peterson, D. A. (2005). Stem cell proliferative history in tis-sue revealed by temporal halogenated thymidine analogue discrimination. Nat. Methods 2, 167-169.
33. Wojtowicz, J. M., and Kee, N. (2006). BrdU assay for neurogenesis in rodents. Nat. Protoc. 1, 1399-1405.
34. Yokochi, T., and Gilbert, D. M. (2007). Replication labeling with halogenated thymidine analogues. Curr. Protoc. Cell Biol. Chapter 22, Unit 22 10, PMID 18228503.