메뉴 건너뛰기




Volumn 37, Issue 7, 2012, Pages 654-660

Ganciclovir ophthalmic gel 0.15%: Safety and efficacy of a new treatment for herpes simplex keratitis

Author keywords

Acyclovir; Adenoviral keratoconjunctivitis; Ganciclovir ophthalmic gel 0.15 ; Herpes simplex keratitis; Trifluridine

Indexed keywords

ACICLOVIR; GANCICLOVIR; TRIFLURIDINE;

EID: 84862160795     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.3109/02713683.2012.692846     Document Type: Article
Times cited : (37)

References (47)
  • 2
    • 3242663234 scopus 로고    scopus 로고
    • Clinical manifestations and treatment modalities in herpes simplex virus of the ocular anterior segment
    • DOI 10.1097/00004397-200404430-00012
    • Khan BF, Pavan-Langston D. Clinical manifestations and treatment modalities in herpes simplex virus of the ocular anterior segment. Int Ophthalmol Clin 2004;44:103-133. (Pubitemid 38955665)
    • (2004) International Ophthalmology Clinics , vol.44 , Issue.3 , pp. 103-133
    • Khan, B.F.1    Pavan-Langston, D.2
  • 4
    • 0035171263 scopus 로고    scopus 로고
    • Herpes simplex virus epidemiology and ocular importance
    • DOI 10.1097/00003226-200101000-00001
    • Liesegang TJ. Herpes simplex virus epidemiology and ocular importance. Cornea 2001;20:1-13. (Pubitemid 32038147)
    • (2001) Cornea , vol.20 , Issue.1 , pp. 1-13
    • Liesegang, T.J.1
  • 5
    • 0024319427 scopus 로고
    • Epidemiology of ocular herpes simplex: Incidence in Rochester, Minn, 1950 through 1982
    • Liesegang TJ, Melton LJ 3rd, Daly PJ, Ilstrup DM. Epidemiology of ocular herpes simplex. Incidence in Rochester, Minn, 1950 through 1982. Arch Ophthalmol 1989;107:1155-1159. (Pubitemid 19195642)
    • (1989) Archives of Ophthalmology , vol.107 , Issue.8 , pp. 1155-1159
    • Liesegang, T.J.1    Melton III, L.J.2    Daly, P.J.3    Ilstrup, D.M.4
  • 6
    • 70049098923 scopus 로고    scopus 로고
    • Ganciclovir: A promising topical antiviral gel for herpetic keratitis
    • Kaufman HE. Ganciclovir: a promising topical antiviral gel for herpetic keratitis. Expert Rev Ophthalmol 2009;4:367-375.
    • (2009) Expert Rev Ophthalmol , vol.4 , pp. 367-375
    • Kaufman, H.E.1
  • 7
    • 0004956927 scopus 로고
    • Comparison of specific antiviral agents in herpes simplex keratitis
    • Kaufman HE, Maloney ED, Nesburn AB. Comparison of specific antiviral agents in herpes simplex keratitis. Invest Ophthalmol 1962;1:686-692.
    • (1962) Invest Ophthalmol , vol.1 , pp. 686-692
    • Kaufman, H.E.1    Maloney, E.D.2    Nesburn, A.B.3
  • 8
    • 0000398183 scopus 로고
    • Use of 5-iodo-2′-deoxy-uridine (IDU) in treatment of herpes simplex keratitis
    • Kaufman H, Martola EL, Dohlman C. Use of 5-iodo-2′-deoxy-uridine (IDU) in treatment of herpes simplex keratitis. Arch Ophthalmol 1962;68:235-239.
    • (1962) Arch Ophthalmol , vol.68 , pp. 235-239
    • Kaufman, H.1    Martola, E.L.2    Dohlman, C.3
  • 10
    • 34247882776 scopus 로고    scopus 로고
    • Therapeutic interventions for herpes simplex virus epithelial keratitis
    • CD002898
    • Wilhelmus KR. Therapeutic interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev 2007;1:CD002898.
    • (2007) Cochrane Database Syst Rev , vol.1
    • Wilhelmus, K.R.1
  • 11
    • 38449106082 scopus 로고    scopus 로고
    • Evidence-based treatment of herpes simplex virus keratitis: A systematic review
    • Guess S, Stone DU, Chodosh J. Evidence-based treatment of herpes simplex virus keratitis: a systematic review. Ocul Surf 2007;5:240-250. (Pubitemid 351902645)
    • (2007) Ocular Surface , vol.5 , Issue.3 , pp. 240-250
    • Guess, S.1    Stone, D.U.2    Chodosh, J.3
  • 14
    • 0022425792 scopus 로고
    • Trifluridine-associated conjunctival cicatrization
    • Udell IJ. Trifluridine-associated conjunctival cicatrization. Am J Ophthalmol 1985;99:363-364.
    • (1985) Am J Ophthalmol , vol.99 , pp. 363-364
    • Udell, I.J.1
  • 15
    • 1342302556 scopus 로고    scopus 로고
    • Adenovirus infection in hematopoietic stem cell transplantation: Effect of ganciclovir and impact on survival
    • DOI 10.1016/S1083-8791(03)00102-2, PII S1083879103001022
    • Bruno B, Gooley T, Hackman RC, Davis C, Corey L, Boeckh M. Adenovirus infection in hematopoietic stem cell transplantation: effect of ganciclovir and impact on survival. Biol Blood Marrow Transplant 2003;9:341-352. (Pubitemid 38351819)
    • (2003) Biology of Blood and Marrow Transplantation , vol.9 , Issue.5 , pp. 341-352
    • Bruno, B.1    Gooley, T.2    Hackman, R.C.3    Davis, C.4    Corey, L.5    Boeckh, M.6
  • 16
    • 0024343146 scopus 로고
    • Inhibition of HBV DNA replication by ganciclovir in patients AIDS
    • Locarnini S, Guo K, Lucas R, Gust I. Inhibition of HBV DNA replication by ganciclovir in patients with AIDS. Lancet 1989;2:1225-1226. (Pubitemid 19275485)
    • (1989) Lancet , vol.2 , Issue.8673 , pp. 1225-1226
    • Locarnini, S.1    Guo, K.2    Lucas, R.3    Gust, I.4
  • 17
    • 0023870953 scopus 로고
    • The susceptibility of adenovirus infection to the anti-cytomegalovirus drug, ganciclovir (DHPG)
    • DOI 10.1016/0378-1097(88)90320-5
    • Taylor DL, Jeffries DJ, Taylor-Robinson D, Parkin JM, Tyms AS. The susceptibility of adenovirus infection to the anticytomegalovirus drug, ganciclovir (DHPG). FEMS Microbiol Lett 1988;49: 337-341. (Pubitemid 18077621)
    • (1988) FEMS Microbiology Letters , vol.49 , Issue.3 , pp. 337-341
    • Taylor, D.L.1    Jeffries, D.J.2    Taylor-Robinson, D.3    Parkin, J.M.4    Tyms, A.S.5
  • 19
    • 70049107449 scopus 로고    scopus 로고
    • Ganciclovir ophthalmic gel, 0.15%: A valuable tool for treating ocular herpes
    • Colin J. Ganciclovir ophthalmic gel, 0.15%: a valuable tool for treating ocular herpes. Clin Ophthalmol 2007;1:441-453.
    • (2007) Clin Ophthalmol , vol.1 , pp. 441-453
    • Colin, J.1
  • 20
    • 84862226306 scopus 로고    scopus 로고
    • package insert Rochester, NY: Bausch & Lomb, Inc
    • Zirgan [package insert]. Rochester, NY: Bausch & Lomb, Inc; 2009.
    • (2009) Zirgan
  • 24
    • 0021161929 scopus 로고
    • Efficacy of BW759 (9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine) against herpes simplex virus type 1 keratitis in rabbits
    • Trousdale MD, Nesburn AB, Willey DE, Taaid H. Efficacy of BW759 (9-[[2-hydroxy-1(hydroxymethyl)ethoxy]methyl]guanine) against herpes simplex virus type 1 keratitis in rabbits. Curr Eye Res 1984;3:1007-1015. (Pubitemid 14030475)
    • (1984) Current Eye Research , vol.3 , Issue.8 , pp. 1007-1015
    • Trousdale, M.D.1    Nesburn, A.B.2    Willey, D.E.3    Taaid, H.4
  • 25
    • 0023143451 scopus 로고
    • Anti-herpes simplex virus (HSV) effect of 9-(1,3-dihydroxy-2- propoxymethyl)guanine (DHPG) in rabbit cornea
    • Shiota H, Naito T, Mimura Y. Anti-herpes simplex virus (HSV) effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG) in rabbit cornea. Curr Eye Res 1987;6:241-245. (Pubitemid 17007680)
    • (1987) Current Eye Research , vol.6 , Issue.1 , pp. 241-245
    • Shiota, H.1    Naito, T.2    Mimura, Y.3
  • 27
    • 84862200193 scopus 로고
    • Ocular pharmacokinetics of topically-applied ganciclovir in rabbits with intact or removed epithelium
    • Chibrel H, Elena PP, Khosravi E. Ocular pharmacokinetics of topically-applied ganciclovir in rabbits with intact or removed epithelium. Invest Ophthalmol Vis Sci 1993;34:1712-1734.
    • (1993) Invest Ophthalmol Vis Sci , vol.34 , pp. 1712-1734
    • Chibrel, H.1    Elena, P.P.2    Khosravi, E.3
  • 29
    • 84862226307 scopus 로고    scopus 로고
    • Center for Drug Evaluation and Research Available at Accessed 3 June 2011
    • Food and Drug Administration. Center for Drug Evaluation and Research. Zirgan Clin Pharmacol Biopharm Rev Available at http://www.accessdata.fda.gov/ drugsatfda-docs/nda/2009/022211-zirgan-toc.cfm. Accessed 3 June 2011.
    • Zirgan Clin Pharmacol Biopharm Rev
  • 31
    • 0025732673 scopus 로고
    • Effects of 9-(1,3-dihydroxy-2-propoxymethyl) guanine (DHPG) eye drops and cyclosporine eye drops in the treatment of herpetic stromal keratitis in rabbits
    • Naito T, Nitta K, Kinouchi Y, Shiota H, Mimura Y. Effects of 9-(1,3-dihydroxy-2-propoxymethyl) guanine (DHPG) eye drops and cyclosporine eye drops in the treatment of herpetic stromal keratitis in rabbits. Curr Eye Res 1991;10 Suppl:201-203.
    • (1991) Curr Eye Res , vol.10 , Issue.SUPPL. , pp. 201-203
    • Naito, T.1    Nitta, K.2    Kinouchi, Y.3    Shiota, H.4    Mimura, Y.5
  • 32
    • 0023139847 scopus 로고
    • 2'-nor-cGMP, a new cyclic derivative of 2'NDG, inhibits HSV-1 replication in vitro and in the mouse keratitis model
    • Gordon YJ, Capone A, Sheppard J, Gordon A, Romanowski E, Araullo-Cruz T. 2′-nor-cGMP, a new cyclic derivative of 2′NDG, inhibits HSV-1 replication in vitro and in the mouse keratitis model. Curr Eye Res 1987;6:247-253. (Pubitemid 17007681)
    • (1987) Current Eye Research , vol.6 , Issue.1 , pp. 247-253
    • Gordon, Y.J.1    Capone, A.2    Sheppard, J.3
  • 34
    • 85041817711 scopus 로고    scopus 로고
    • Topical treatment for epithelial herpetic keratitis: Ganciclovir gel vs aciclovir ointment
    • E-abstract 3072
    • Ramirez JB, Baca O, Velasco R, Viggiano D, Erazo J. Topical treatment for epithelial herpetic keratitis: ganciclovir gel vs aciclovir ointment. Invest Ophthalmol Vis Sci 2002;43:E-abstract 3072.
    • (2002) Invest Ophthalmol Vis Sci , vol.43
    • Ramirez, J.B.1    Baca, O.2    Velasco, R.3    Viggiano, D.4    Erazo, J.5
  • 35
    • 79952200522 scopus 로고    scopus 로고
    • Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis
    • CD002898
    • Wilhelmus KR. Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev 2010;12:CD002898.
    • (2010) Cochrane Database Syst Rev , vol.12
    • Wilhelmus, K.R.1
  • 36
    • 70049109673 scopus 로고    scopus 로고
    • Ganciclovir gel - A new topical treatment for herpetic keratitis
    • Foster CS. Ganciclovir gel - a new topical treatment for herpetic keratitis. US Ophthamol Rev Touch Briefings 2008;3:52-56.
    • (2008) US Ophthamol Rev Touch Briefings , vol.3 , pp. 52-56
    • Foster, C.S.1
  • 38
    • 84862184750 scopus 로고    scopus 로고
    • Laboratoires THEA. 63017 Clermont-Ferrand Cedex 2, France. February 8
    • Laboratoires THEA. Virgan 1.5 mg/g eye gel: pharmacovigilance data. 63017 Clermont-Ferrand Cedex 2, France. February 8, 2008.
    • (2008) Virgan 1.5 Mg/g Eye Gel: Pharmacovigilance Data
  • 39
    • 7444256060 scopus 로고    scopus 로고
    • Resistance of herpes simplex virus infections to nucleoside analogues in HIV-infected patients
    • DOI 10.1086/422364
    • Levin MJ, Bacon TH, Leary JJ. Resistance of herpes simplex virus infections to nucleoside analogues in HIV-infected patients. Clin Infect Dis 2004;39 Suppl 5:S248-S257. (Pubitemid 39447300)
    • (2004) Clinical Infectious Diseases , vol.39 , Issue.SUPPL. 5
    • Levin, M.J.1    Bacon, T.H.2    Leary, J.J.3
  • 40
    • 0037244124 scopus 로고    scopus 로고
    • Herpes simplex virus resistance to acyclovir and penciclovir after two decades of antiviral therapy
    • DOI 10.1128/CMR.16.1.114-128.2003
    • Bacon TH, Levin MJ, Leary JJ, Sarisky RT, Sutton D. Herpes simplex virus resistance to acyclovir and penciclovir after two decades of antiviral therapy. Clin Microbiol Rev 2003;16:114-128. (Pubitemid 36114710)
    • (2003) Clinical Microbiology Reviews , vol.16 , Issue.1 , pp. 114-128
    • Bacon, T.H.1    Levin, M.J.2    Leary, J.J.3    Sarisky, R.T.4    Sutton, D.5
  • 41
    • 50949091696 scopus 로고    scopus 로고
    • Acyclovir-resistant corneal HSV-1 isolates from patients with herpetic keratitis
    • Duan R, de Vries RD, Osterhaus AD, Remeijer L, Verjans GM. Acyclovir-resistant corneal HSV-1 isolates from patients with herpetic keratitis. J Infect Dis 2008;198:659-663.
    • (2008) J Infect Dis , vol.198 , pp. 659-663
    • Duan, R.1    De Vries, R.D.2    Osterhaus, A.D.3    Remeijer, L.4    Verjans, G.M.5
  • 42
    • 24944434690 scopus 로고    scopus 로고
    • Treatment of herpetic keratitis
    • Tabbara KF. Treatment of herpetic keratitis. Ophthalmology 2005;112:1640.
    • (2005) Ophthalmology , vol.112 , pp. 1640
    • Tabbara, K.F.1
  • 43
    • 70049102631 scopus 로고    scopus 로고
    • Ganciclovir effects in adenoviral keratoconjunctivitis
    • Abstract 3111-B253
    • Tabbara KF, Jarade EF. Ganciclovir effects in adenoviral keratoconjunctivitis. Invest Ophthalmol Vis Sci 2001;42:S579. Abstract 3111-B253.
    • (2001) Invest Ophthalmol Vis Sci , vol.42
    • Tabbara, K.F.1    Jarade, E.F.2
  • 44
    • 84862236659 scopus 로고    scopus 로고
    • Ganciclovir 0.15% gel, a new treatment in epidemic keratoconjunctivitis (EKC)
    • Vérin PH, Mortemousque B, Barach D. Ganciclovir 0.15% gel, a new treatment in epidemic keratoconjunctivitis (EKC). Ophthalmic Res 1997;29(suppl 1):12-27.
    • (1997) Ophthalmic Res , vol.29 , Issue.SUPPL. 1 , pp. 12-27
    • Vérin, P.H.1    Mortemousque, B.2    Barach, D.3
  • 47
    • 77952346397 scopus 로고    scopus 로고
    • US Department of Health and Human Services Application Number 22-211. Silver Spring, MD: Center for Drug Evaluation and Research
    • US Department of Health and Human Services. NDA Approval Letter, Application Number 22-211. Silver Spring, MD: Center for Drug Evaluation and Research. 2009.
    • (2009) NDA Approval Letter


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.