Venous thromboembolism after major orthopaedic surgery: A population-based cohort study

Internal and Emergency Medicine

Volumn 7, Issue 3, 2012, Pages 243-249

  Imberti, Davide ^a   Bianchi, Cosetta ^b   Zambon, Antonella ^c   Parodi, Andrea ^c   Merlino, Luca ^d   Gallerani, Massimo ^a   Corrao, Giovanni ^c  

^a UNIVERSITY HOSPITAL OF FERRARA   (Italy)

^b Pricing and HEOR Bayer Schering Pharma   (Italy)

^c UNIVERSITY OF MILANO BICOCCA   (Italy)

^d Operative Unit of Territorial Health Services   (Italy)

Author keywords

Orthopedic surgery; Risk factors; Venous thromboembolism

Indexed keywords

FIBRINOLYTIC AGENT;

AGED; ARTICLE; COHORT ANALYSIS; CONFIDENCE INTERVAL; FACTUAL DATABASE; FEMALE; HUMAN; INCIDENCE; ITALY; MALE; MULTIVARIATE ANALYSIS; ORTHOPEDIC SURGERY; RETROSPECTIVE STUDY; RISK; RISK FACTOR; STATISTICAL MODEL; VENOUS THROMBOEMBOLISM;

AGED; COHORT STUDIES; CONFIDENCE INTERVALS; DATABASES, FACTUAL; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; INCIDENCE; ITALY; LOGISTIC MODELS; MALE; MULTIVARIATE ANALYSIS; ODDS RATIO; ORTHOPEDIC PROCEDURES; RETROSPECTIVE STUDIES; RISK FACTORS; VENOUS THROMBOEMBOLISM;

EID: 84862156588     PISSN: 18280447     EISSN: 19709366     Source Type: Journal    
DOI: 10.1007/s11739-011-0567-x     Document Type: Article

References (35)

1. Shorr AF, Kwong LM, Sarnes M, Happe L, Farrelly E, Mody-Patel N (2007) Venous thromboembolism after orthopedic surgery: implications of the choice for prophylaxis. Thromb Res 121: 17-24.
2. Bergqvist D, Benoni G, Bjorgell O, Fredin H, Hedlundh U, Nicolas S, Nilsson P, Nylander G (1996) Low-molecular-weight heparin (enoxaparin) as prophylaxis against venous thromboembolism after total hip replacement. N Engl J Med 335: 696-700.
3. Comp PC, Spiro TE, Friedman RJ, Whitsett TL, Johnson GJ, Gardiner GA, Gardiner GA Jr, Landon GC, Jove M (2001) Prolonged enoxaparin therapy to prevent venous thromboembolism after primary hip or knee replacement. Enoxaparin Clinical Trial Group. J Bone Joint Surg Am 83-A: 336-345.
4. Nakase J, Toribatake Y, Mouri Y, Seki H, Kitaoka K, Tomita K (2009) Heparin versus danaproid for prevention of venous thromboembolism after hip surgery. J Orthop Surg (Hong Kong) 17: 6-9.
5. Geerts WH, Bergqvist D, Pineo GF, Heit JA, Samama CM, Lassen MR, Colwell CW (2008) Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 133: 381S-453S.
6. Alikhan R, Peters F, Wilmott R, Cohen AT (2004) Fatal pulmonary embolism in hospitalised patients: a necropsy review. J Clin Pathol 57: 1254-1257.
7. Eikelboom JW, Quinlan DJ, Douketis JD (2001) Extended-duration prophylaxis against venous thromboembolism after total hip or knee replacement: a meta-analysis of the randomised trials. Lancet 358: 9-15.
8. Ganz DA, Glynn RJ, Mogun H, Knight EL, Bohn RL, Avorn J (2000) Adherence to guidelines for oral anticoagulation after venous thrombosis and pulmonary embolism. J Gen Intern Med 15: 776-781.
9. Geerts W (2009) Prevention of venous thromboembolism: a key patient safety priority. J Thromb Haemost 7(Suppl 1): 1-8.
10. Hull RD, Pineo GF, Stein PD, Mah AF, MacIsaac SM, Dahl OE, Butcher M, Brant RF, Ghali WA, Bergqvist D, Raskob GE (2001) Extended out-of-hospital low-molecular-weight heparin prophylaxis against deep venous thrombosis in patients after elective hip arthroplasty: a systematic review. Ann Intern Med 135: 858-869.
11. Imberti D, Prisco D (2005) Venous thromboembolism prophylaxis in medical patients: future perspectives. Thromb Res 116: 365-375.
12. Mantilla CB, Horlocker TT, Schroeder DR, Berry DJ, Brown DL (2002) Frequency of myocardial infarction, pulmonary embolism, deep venous thrombosis, and death following primary hip or knee arthroplasty. Anesthesiology 96: 1140-1146.
13. Leclerc JR, Gent M, Hirsh J, Geerts WH, Ginsberg JS (1998) The incidence of symptomatic venous thromboembolism after enoxaparin prophylaxis in lower extremity arthroplasty: a cohort study of 1, 984 patients. Canadian Collaborative Group. Chest 114: 115S-118S.
14. Verhaeghe R (2005) Extended prophylaxis of venous thromboembolism in major orthopaedic surgery. Acta Orthop Belg 71: 255-259.
15. Corrao G, Cesana G, Merlino L (2008) Pharmacoepidemiological research and linking of electronic databases available in the Italian region of Lombardy. Biomed Stat Clin Epidemiol 2: 117-125.
16. ISTAT: Censimento Generale della Popolazione e delle Abitazioni. Available at: http://www. dawinciistatit/MD.
17. Claes N, Buntinx F, Vijgen J, Arnout J, Vermylen J, Fieuws S, van LH (2005) The Belgian Improvement Study on Oral Anticoagulation Therapy: a randomized clinical trial. Eur Heart J 26: 2159-2165.
18. Edmonds MJ, Crichton TJ, Runciman WB, Pradhan M (2004) Evidence-based risk factors for postoperative deep vein thrombosis. ANZ J Surg 74: 1082-1097.
19. Gangireddy C, Rectenwald JR, Upchurch GR, Wakefield TW, Khuri S, Henderson WG, Henke PK (2007) Risk factors and clinical impact of postoperative symptomatic venous thromboembolism. J Vasc Surg 45: 335-341.
20. Glynn RJ, Danielson E, Fonseca FA, Genest J, Gotto AM Jr, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Ridker PM (2009) A randomized trial of rosuvastatin in the prevention of venous thromboembolism. N Engl J Med 360: 1851-1861.
21. Isma N, Svensson PJ, Gottsater A, Lindblad B (2009) Prospective analysis of risk factors and distribution of venous thromboembolism in the population-based Malmo Thrombophilia Study (MATS). Thromb Res 124: 663-666.
22. Lacut K, van der Maaten J, Le GG, Cornily G, Mottier D, Oger E (2008) Antiplatelet drugs and risk of venous thromboembolism: results from the EDITH case-control study. Haematologica 93: 1117-1118.
23. Jewell NP (2004) Statistics for epidemiology. Chapman and Hall, Boca Raton.
24. Schabenberger O (2008) Introducing the GLIMMIX procedure for generalized linear mixed models. SAS Institute Inc., Cary (2008).
25. Hanley JA, McNeil BJ (1982) The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 143: 29-36.
26. The Thrombosis Interest Group of Canada: Clinical Guide-The prevention of deep vein thrombosis in medical patients, 2008. Available at http://www. tigc. org/pdf/PrevDVTMedPat. pdf.
27. Ageno W, Squizzato A, Garcia D, Imberti D (2006) Epidemiology and risk factors of venous thromboembolism. Semin Thromb Hemost 32: 651-658.
28. Severinsen MT, Johnsen SP, Tjonneland A, Overvad K, Dethlefsen C, Kristensen SR (2010) Body height and sex-related differences in incidence of venous thromboembolism: a Danish follow-up study. Eur J Intern Med 21: 268-272.
29. Davidson HC, Mazzu D, Gage BF, Jeffrey RB (1996) Screening for deep venous thrombosis in asymptomatic postoperative orthopedic patients using color Doppler sonography: analysis of prevalence and risk factors. AJR Am J Roentgenol 166: 659-662.
30. Samama MM (2000) An epidemiologic study of risk factors for deep vein thrombosis in medical outpatients: the Sirius study. Arch Intern Med 160: 3415-3420.
31. Imberti D, Dallasta C (2008) Clinical benefits of rivaroxaban for thromboprophylaxis after major orthopaedic surgery. Adv Orthop 1: 8-16.
32. Blom JW, Doggen CJ, Osanto S, Rosendaal FR (2005) Malignancies, prothrombotic mutations, and the risk of venous thrombosis. JAMA 293: 715-722.
33. Corrao G, Zambon A, Conti V, Nicotra F, La VC, Fornari C, Cesana G, Contiero P, Tagliabue G, Nappi RE, Merlino L (2008) Menopause hormone replacement therapy and cancer risk: an Italian record linkage investigation. Ann Oncol 19: 150-155.
34. Randelli F, Biggi F, Della RG, Grossi P, Imberti D, Landolfi R, Palareti G, Prisco D. Italian intersociety consensus statement on antithrombotic prophylaxis in hip and knee replacement and in femoral neck fracture surgery. J Orthop Traumatol. doi: 10. 1007/s10195-010-0125-8.
35. Fattore G, Colangelo I, Martelli E, Cheli A, Del Sasso L (2004) Methods and costs of venous thromboembolism prophylaxis in orthopedic surgery in Italy. Pharmacoecon Italian Res Articles 6: 69-80.