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Volumn 24, Issue 4, 2012, Pages 414-418

Adjuvant therapy of gastrointestinal stromal tumors

Author keywords

adjuvant; dose; gastrointestinal stromal tumors; imatinib

Indexed keywords

IMATINIB; MASITINIB; NILOTINIB; PLACEBO; SORAFENIB; SUNITINIB; VATALANIB;

EID: 84862147870     PISSN: 10408746     EISSN: 1531703X     Source Type: Journal    
DOI: 10.1097/CCO.0b013e328353d774     Document Type: Review
Times cited : (10)

References (38)
  • 1
    • 33749459756 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors
    • Miettinen M, Lasota J. Gastrointestinal stromal tumors. Arch Pathol Lab Med 2006; 130:1466-1478.
    • (2006) Arch Pathol Lab Med , vol.130 , pp. 1466-1478
    • Miettinen, M.1    Lasota, J.2
  • 2
    • 77957144342 scopus 로고    scopus 로고
    • Survival of patients with multiple primary malignancies: A study of 783 patients with gastrointestinal stromal tumor
    • Pandurengan RK, Dumon AG, Araujo DM, et al. Survival of patients with multiple primary malignancies: a study of 783 patients with gastrointestinal stromal tumor. Ann Oncol 2010; 21:2107-2111.
    • (2010) Ann Oncol , vol.21 , pp. 2107-2111
    • Pandurengan, R.K.1    Dumon, A.G.2    Araujo, D.M.3
  • 5
    • 78049483265 scopus 로고    scopus 로고
    • Pattern of recurrence in patients with ruptured primary gastrointestinal stromal tumour
    • Hohenberger P, Ronellenfitsch U, Oladeji O, et al. Pattern of recurrence in patients with ruptured primary gastrointestinal stromal tumour. Br J Surg 2010; 97:1854-1859.
    • (2010) Br J Surg , vol.97 , pp. 1854-1859
    • Hohenberger, P.1    Ronellenfitsch, U.2    Oladeji, O.3
  • 6
    • 80052963619 scopus 로고    scopus 로고
    • Validation of the Joensuu risk criteria for primary resectable gastrointestinal stromal tumour - The impact of tumour rupture on patient outcomes
    • Rutkowski P, Bylina E, Wozniak A, et al. Validation of the Joensuu risk criteria for primary resectable gastrointestinal stromal tumour-the impact of tumour rupture on patient outcomes. Eur J Surg Oncol 2011; 37:890-896.
    • (2011) Eur J Surg Oncol , vol.37 , pp. 890-896
    • Rutkowski, P.1    Bylina, E.2    Wozniak, A.3
  • 7
    • 78649673624 scopus 로고    scopus 로고
    • Relation of tumor pathologic and molecular features to outcome after surgical resection of localized primary gastrointestinal stromal tumor (GIST): Results of the intergroup phase III trial ACOSOG Z9001
    • abstr.10006
    • Corless CL, Ballman KV, Antonescu C, et al. Relation of tumor pathologic and molecular features to outcome after surgical resection of localized primary gastrointestinal stromal tumor (GIST): results of the intergroup phase III trial ACOSOG Z9001. J Clin Oncol 2010; 28 (15 Suppl.):abstr.10006.
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL.
    • Corless, C.L.1    Ballman, K.V.2    Antonescu, C.3
  • 8
    • 78650972191 scopus 로고    scopus 로고
    • Integrative genomic characterization and a genomic staging system for gastrointestinal stromal tumors
    • Ylipaa A, Hunt KK, Yang J, et al. Integrative genomic characterization and a genomic staging system for gastrointestinal stromal tumors. Cancer 2011; 117:380-389.
    • (2011) Cancer , vol.117 , pp. 380-389
    • Ylipaa, A.1    Hunt, K.K.2    Yang, J.3
  • 9
    • 84856513068 scopus 로고    scopus 로고
    • Mitotic checkpoints and chromosome instability are strong predictors of clinical outcome in gastrointestinal stromal tumors
    • Lagarde P, Perot G, Kauffmann A, et al. Mitotic checkpoints and chromosome instability are strong predictors of clinical outcome in gastrointestinal stromal tumors. Clin Cancer Res 2012; 18:826-838.
    • (2012) Clin Cancer Res , vol.18 , pp. 826-838
    • Lagarde, P.1    Perot, G.2    Kauffmann, A.3
  • 10
    • 62849096370 scopus 로고    scopus 로고
    • Adjuvant imatinib mesylate after resection of localized, primary gastrointestinal stromal tumour: A randomized, double-blind, placebo-controlled trial
    • DeMatteo RP, Ballman KV, Antonescu CR, et al. Adjuvant imatinib mesylate after resection of localized, primary gastrointestinal stromal tumour: a randomized, double-blind, placebo-controlled trial. Lancet 2009; 373:1097-1104.
    • (2009) Lancet , vol.373 , pp. 1097-1104
    • Dematteo, R.P.1    Ballman, K.V.2    Antonescu, C.R.3
  • 11
    • 77949898532 scopus 로고    scopus 로고
    • Comparison of two doses of imatinib for the treatment of unresectable or metastatic gastrointestinal stromal tumors: A meta-analysis of 1640 patients
    • Gastrointestinal Stromal Tumor Meta-Analysis Group
    • Gastrointestinal Stromal Tumor Meta-Analysis Group. Comparison of two doses of imatinib for the treatment of unresectable or metastatic gastrointestinal stromal tumors: a meta-analysis of 1640 patients. J Clin Oncol 2010; 28:1247-1253.
    • (2010) J Clin Oncol , vol.28 , pp. 1247-1253
  • 12
    • 67650306170 scopus 로고    scopus 로고
    • Imatinib plasma levels are correlated with clinical benefit in patients with unresectable/metastatic gastrointestinal stromal tumors
    • Demetri GD, Wang Y, Wehrle E, et al. Imatinib plasma levels are correlated with clinical benefit in patients with unresectable/metastatic gastrointestinal stromal tumors. J Clin Oncol 2009; 27:3141-3147.
    • (2009) J Clin Oncol , vol.27 , pp. 3141-3147
    • Demetri, G.D.1    Wang, Y.2    Wehrle, E.3
  • 13
    • 77951922479 scopus 로고    scopus 로고
    • Cross-sectional study of imatinib plasma trough levels in patients with advanced gastrointestinal stromal tumors: Impact of gastrointestinal resection on exposure to imatinib
    • Yoo C, Ryu M, Kang BW, et al. Cross-sectional study of imatinib plasma trough levels in patients with advanced gastrointestinal stromal tumors: impact of gastrointestinal resection on exposure to imatinib. J Clin Oncol 2010; 28:1554-1559.
    • (2010) J Clin Oncol , vol.28 , pp. 1554-1559
    • Yoo, C.1    Ryu, M.2    Kang, B.W.3
  • 14
    • 80053465153 scopus 로고    scopus 로고
    • Twelve versus 36 months of adjuvant imatinib (IM) as treatment of operable GIST with a high risk of recurrence: Final results of a randomized trial (SSGXVII/AIO)
    • abstr. LBA1
    • Joensuu H, Eriksson M, Hatrmann J, et al. Twelve versus 36 months of adjuvant imatinib (IM) as treatment of operable GIST with a high risk of recurrence: final results of a randomized trial (SSGXVII/AIO). J Clin Oncol 2011; 29(18 Suppl.):abstr. LBA1.
    • (2011) J Clin Oncol , vol.29 , Issue.18 SUPPL.
    • Joensuu, H.1    Eriksson, M.2    Hatrmann, J.3
  • 15
    • 79952451365 scopus 로고    scopus 로고
    • Postoperative imatinib in patients with intermediate or high risk gastrointestinal stromal tumor
    • Li J, Gong JF, Wu AW, Shen L. Postoperative imatinib in patients with intermediate or high risk gastrointestinal stromal tumor. Eur J Surg Oncol 2011; 37:319-324.
    • (2011) Eur J Surg Oncol , vol.37 , pp. 319-324
    • Li, J.1    Gong, J.F.2    Wu, A.W.3    Shen, L.4
  • 16
    • 80255138368 scopus 로고    scopus 로고
    • Adjuvant imatinib treatment after R0 resection for patients with high-risk gastrointestinal stromal tumors: A median follow-up of 44 months
    • Jiang WZ, Guan GX, Lu HS, et al. Adjuvant imatinib treatment after R0 resection for patients with high-risk gastrointestinal stromal tumors: a median follow-up of 44 months. J Surg Oncol 2011; 104:760-764.
    • (2011) J Surg Oncol , vol.104 , pp. 760-764
    • Jiang, W.Z.1    Guan, G.X.2    Lu, H.S.3
  • 17
    • 62149141753 scopus 로고    scopus 로고
    • A randomized, phase II study of preoperative plus postoperative imatinib in GIST: Evidence of rapid radiographic response and temporal induction of tumor cell apoptosis
    • McAuliffe JC, Hunt KK, Lazar AJ, et al. A randomized, phase II study of preoperative plus postoperative imatinib in GIST: evidence of rapid radiographic response and temporal induction of tumor cell apoptosis. Ann Surg Oncol 2009; 16:910-919.
    • (2009) Ann Surg Oncol , vol.16 , pp. 910-919
    • McAuliffe, J.C.1    Hunt, K.K.2    Lazar, A.J.3
  • 18
    • 58149399145 scopus 로고    scopus 로고
    • Phase II trial of neoadjuvant/adjuvant imatinib mesylate (IM) for advanced primary and metastatic/recurrent operable gastrointestinal stromal tumor (GIST): Early results of RTOG 0132/ACRIN 6665
    • Eisenberg BL, Harris J, Blanke CD, et al. Phase II trial of neoadjuvant/adjuvant imatinib mesylate (IM) for advanced primary and metastatic/recurrent operable gastrointestinal stromal tumor (GIST): early results of RTOG 0132/ACRIN 6665. J Surg Oncol 2009; 99:42-47.
    • (2009) J Surg Oncol , vol.99 , pp. 42-47
    • Eisenberg, B.L.1    Harris, J.2    Blanke, C.D.3
  • 19
    • 80355147509 scopus 로고    scopus 로고
    • Follow-up results after 9 years (yrs) of the ongoing, phase II B2222 trial of imatinib mesylate (IM) in patients (pts) with metastatic or unresectable KIT + gastrointestinal stromal tumors (GIST)
    • abstr 10016
    • Von Mehren M, Heinrich MC, Joensuu H, et al. Follow-up results after 9 years (yrs) of the ongoing, phase II B2222 trial of imatinib mesylate (IM) in patients (pts) with metastatic or unresectable KIT + gastrointestinal stromal tumors (GIST). in J Clin Oncol 2011; 29 (15 Suppl.):abstr. 10016.
    • (2011) Int. J Clin Oncol , vol.29 , Issue.15 SUPPL.
    • Von Mehren, M.1    Heinrich, M.C.2    Joensuu, H.3
  • 20
    • 84855330478 scopus 로고    scopus 로고
    • Who are the long responders to imatinib (IM) in patients with advanced GIST? Results of the BFR14 prospective French Sarcoma Group randomized phase III trial
    • abstr 10048
    • Blesius A, Cassier PA, Ray-Coquard IL, et al. Who are the long responders to imatinib (IM) in patients with advanced GIST? Results of the BFR14 prospective French Sarcoma Group randomized phase III trial. J Clin Oncol 2011; 29 (15 Suppl.):abstr. 10048.
    • (2011) J Clin Oncol , vol.29 , Issue.15 SUPPL.
    • Blesius, A.1    Cassier, P.A.2    Ray-Coquard, I.L.3
  • 21
    • 77957341199 scopus 로고    scopus 로고
    • Discontinuation of imatinib in patients with advanced gastrointestinal stromal tumours after 3 years of treatment: An open-label multicentre randomized phase 3 trial
    • Le Cesne A, Ray-Coquard I, Bui BN, et al. Discontinuation of imatinib in patients with advanced gastrointestinal stromal tumours after 3 years of treatment: an open-label multicentre randomized phase 3 trial. Lancet Oncol 2010; 11:942-949.
    • (2010) Lancet Oncol , vol.11 , pp. 942-949
    • Le Cesne, A.1    Ray-Coquard, I.2    Bui, B.N.3
  • 22
    • 79953074376 scopus 로고    scopus 로고
    • Risk of relapse with imatinib (IM) discontinuation at 5 years in advanced GIST patients: Results of the prospective BFR14 randomized phase III study comparing interruption versus continuation of im at 5 years of treatment: A French Sarcoma Group Study
    • abstr 10032
    • Ray-Coquard I, Bui BN, Adenis A, et al. Risk of relapse with imatinib (IM) discontinuation at 5 years in advanced GIST patients: results of the prospective BFR14 randomized phase III study comparing interruption versus continuation of IM at 5 years of treatment: a French Sarcoma Group Study. J Clin Oncol 2010; 28 (16 Suppl.):abstr. 10032.
    • (2010) J Clin Oncol , vol.28 , Issue.16 SUPPL.
    • Ray-Coquard, I.1    Bui, B.N.2    Adenis, A.3
  • 23
    • 84857641974 scopus 로고    scopus 로고
    • Time to secondary resistance (TSR) after interruption of imatinib (IM) in advanced GIST: Updated results of the prospective French Sarcoma Group randomized phase III trial on longterm survival
    • abstr 10015
    • Le Cesne A, Ray-Coquard IL, Bui BN, et al. Time to secondary resistance (TSR) after interruption of imatinib (IM) in advanced GIST: updated results of the prospective French Sarcoma Group randomized phase III trial on longterm survival. J Clin Oncol 2011; 29 (15 Suppl.):abstr. 10015.
    • (2011) J Clin Oncol , vol.29 , Issue.15 SUPPL.
    • Le Cesne, A.1    Ray-Coquard, I.L.2    Bui, B.N.3
  • 24
    • 84862120918 scopus 로고    scopus 로고
    • Phase II trial of neoadjuvant/adjuvant imatinib mesylate (IM) for advanced primary and metastatic/recurrent operable gastrointestinal stromal tumor (GIST): Long-term follow-up results of RTOG 0132
    • abstr 10057
    • Wang D, Zhang Q, Blanke CD, et al. Phase II trial of neoadjuvant/adjuvant imatinib mesylate (IM) for advanced primary and metastatic/recurrent operable gastrointestinal stromal tumor (GIST): long-term follow-up results of RTOG 0132. J Clin Oncol 2011; 29 (15 Suppl.):abstr. 10057.
    • (2011) J Clin Oncol , vol.29 , Issue.15 SUPPL.
    • Wang, D.1    Zhang, Q.2    Blanke, C.D.3
  • 26
    • 77951878436 scopus 로고    scopus 로고
    • Phase II study of oral masitinib mesylate in imatinib-na?̈ve patients with locally advanced or metastatic gastro-intestinal stromal tumour (GIST)
    • Le Cesne A, Blay JY, Bui BN, et al. Phase II study of oral masitinib mesylate in imatinib-na?̈ve patients with locally advanced or metastatic gastro-intestinal stromal tumour (GIST). Eur J Cancer 2010; 46:1344-1351.
    • (2010) Eur J Cancer , vol.46 , pp. 1344-1351
    • Le Cesne, A.1    Blay, J.Y.2    Bui, B.N.3
  • 27
    • 84864409444 scopus 로고    scopus 로고
    • Overall survival benefit with masitinib mesylate in imatinib-na?̈ve, locally advanced, or metastatic gastrointestinal stromal tumor (GIST): 4-years follow-up of the French Sarcoma Group phase II trial
    • abstr 85
    • Blay J, Le Cesne A, Bui BN, et al. Overall survival benefit with masitinib mesylate in imatinib-na?̈ve, locally advanced, or metastatic gastrointestinal stromal tumor (GIST): 4-years follow-up of the French Sarcoma Group phase II trial. J Clin Oncol 2011; 29 (4 Suppl.):abstr. 85.
    • (2011) J Clin Oncol , vol.29 , Issue.4 SUPPL.
    • Blay, J.1    Le Cesne, A.2    Bui, B.N.3
  • 29
    • 79951529219 scopus 로고    scopus 로고
    • Phase II trial of nilotinib as third-line therapy for gastrointestinal stromal tumor (GIST) patients in Japan
    • abstr 10015
    • Nishida T, Sawaki A, Doi T, et al. Phase II trial of nilotinib as third-line therapy for gastrointestinal stromal tumor (GIST) patients in Japan. J ClinOncol 2010; 28 (15 Suppl.):abstr. 10015.
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL.
    • Nishida, T.1    Sawaki, A.2    Doi, T.3
  • 30
    • 79951523462 scopus 로고    scopus 로고
    • Phase III trial of nilotinib in patients with advanced gastrointestinal stromal tumor (GIST): First results from ENEST g3
    • abstr 10017
    • Reichardt P, Blay J, Gelderblom H, et al. Phase III trial of nilotinib in patients with advanced gastrointestinal stromal tumor (GIST): first results from ENEST g3. J Clin Oncol 2010; 28(15 Suppl.):abstr. 10017.
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL.
    • Reichardt, P.1    Blay, J.2    Gelderblom, H.3
  • 31
    • 79957615693 scopus 로고    scopus 로고
    • Vatalanib for metastatic gastrointestinal stromal tumour (GIST) resistant to imatinib: Final results of a phase II study
    • Joensuu H, De Braud F, Grignagni G, et al. Vatalanib for metastatic gastrointestinal stromal tumour (GIST) resistant to imatinib: final results of a phase II study. Br J Cancer 2011; 104:1686-1690.
    • (2011) Br J Cancer , vol.104 , pp. 1686-1690
    • Joensuu, H.1    De Braud, F.2    Grignagni, G.3
  • 32
    • 84857519572 scopus 로고    scopus 로고
    • Sorafenib (SOR) in patients (pts) with imatinib (IM) and sunitinib (SU)-resistant (RES) gastrointestinal stromal tumors (GIST): Final results of a University of Chicago phase II consortium trial
    • abstr 10009
    • Kindler HL, Campbell NP, Wroblewski K, et al. Sorafenib (SOR) in patients (pts) with imatinib (IM) and sunitinib (SU)-resistant (RES) gastrointestinal stromal tumors (GIST): final results of a University of Chicago phase II consortium trial. J Clin Oncol 2011; 29 (15 Suppl.):abstr. 10009.
    • (2011) J Clin Oncol , vol.29 , Issue.15 SUPPL.
    • Kindler, H.L.1    Campbell, N.P.2    Wroblewski, K.3
  • 33
    • 79851508006 scopus 로고    scopus 로고
    • Neoadjuvant imatinib in patients with locally advanced non metastatic GIST in the prospective BFR14 trial
    • Blesius A, Cassier PA, Bertucci F, et al. Neoadjuvant imatinib in patients with locally advanced non metastatic GIST in the prospective BFR14 trial. BMC Cancer 2011; 11:72-78.
    • (2011) BMC Cancer , vol.11 , pp. 72-78
    • Blesius, A.1    Cassier, P.A.2    Bertucci, F.3
  • 34
    • 84862150024 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumor (GIST) of the rectum and pararectal space: A French Sarcoma Group (FSG) retrospective review
    • abstr 10055
    • Duffaud F, Cassier PA, Adenis A, et al. Gastrointestinal stromal tumor (GIST) of the rectum and pararectal space: a French Sarcoma Group (FSG) retrospective review. J Clin Oncol 2010; 28 (15 Suppl.):abstr. 10055.
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL.
    • Duffaud, F.1    Cassier, P.A.2    Adenis, A.3
  • 35
    • 79952109599 scopus 로고    scopus 로고
    • Downsizing treatment with tyrosine kinase inhibitors in patients with advanced gastrointestinal stromal tumors improved respectability
    • Sjolund K, Andersson A, Nilsson E, et al. Downsizing treatment with tyrosine kinase inhibitors in patients with advanced gastrointestinal stromal tumors improved respectability. World J Surg 2010; 34:2090-2097.
    • (2010) World J Surg , vol.34 , pp. 2090-2097
    • Sjolund, K.1    Andersson, A.2    Nilsson, E.3
  • 36
    • 77951814300 scopus 로고    scopus 로고
    • Postimatinib surgery in advanced/metastaticGIST: Is it worthwhile in all patients?
    • Mussi C, Ronellenfitsch U, Jakob J, et al. Postimatinib surgery in advanced/metastaticGIST: is it worthwhile in all patients? AnnOncol2010; 21:403-408.
    • (2010) AnnOncol , vol.21 , pp. 403-408
    • Mussi, C.1    Ronellenfitsch, U.2    Jakob, J.3
  • 37
    • 78349295591 scopus 로고    scopus 로고
    • Surgical management in metastatic gastrointestinal stromal tumor (GIST) patients after imatinib mesylate treatment
    • Yeh CN, Chen TW, Tseng JH, et al. Surgical management in metastatic gastrointestinal stromal tumor (GIST) patients after imatinib mesylate treatment. J Surg Oncol 2010; 102:599-603.
    • (2010) J Surg Oncol , vol.102 , pp. 599-603
    • Yeh, C.N.1    Chen, T.W.2    Tseng, J.H.3
  • 38
    • 77149155973 scopus 로고    scopus 로고
    • Cytoreductive surgery in patients with metastatic gastrointestinal stromal tumor treated with sunitinib malate
    • Raut CP, Wang Q, Manola J, et al. Cytoreductive surgery in patients with metastatic gastrointestinal stromal tumor treated with sunitinib malate. Ann Surg Oncol 2010; 17:407-415.
    • (2010) Ann Surg Oncol , vol.17 , pp. 407-415
    • Raut, C.P.1    Wang, Q.2    Manola, J.3


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