Monoclonal gammopathy of undetermined significance and risk of infections: A population-based study

Haematologica

Volumn 97, Issue 6, 2012, Pages 854-858

  Kristinsson, Sigurdur Y ^a   Tang, Min ^b   Pfeiffer, Ruth M ^c   Björkholm, Magnus ^a   Goldin, Lynn R ^c   Blimark, Cecilie ^d   Mellqvist, Ulf Henrik ^d   Wahlin, Anders ^e   Turesson, Ingemar ^f   Landgren, Ola ^a,c  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^e UMEÅ UNIVERSITY   (Sweden)

^f LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Bacteria; Infections; Monoclonal gammopathy of undetermined significance; Multiple myeloma; Virus

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; M PROTEIN;

ADULT; AGED; ARTICLE; CELLULITIS; CONTROLLED STUDY; ENDOCARDITIS; FEMALE; FOLLOW UP; HERPES ZOSTER; HUMAN; INFECTION RISK; INFLUENZA; MAJOR CLINICAL STUDY; MALE; MENINGITIS; MONOCLONAL IMMUNOGLOBULINEMIA; MULTIPLE MYELOMA; OSTEOMYELITIS; PNEUMONIA; POPULATION BASED CASE CONTROL STUDY; PYELONEPHRITIS; SEPTICEMIA; WALDENSTROEM MACROGLOBULINEMIA;

ADULT; AGED; AGED, 80 AND OVER; BACTERIAL INFECTIONS; CASE-CONTROL STUDIES; FEMALE; HUMANS; IMMUNOGLOBULINS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE; RISK; SWEDEN; VIRUS DISEASES;

EID: 84862146052     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2011.054015     Document Type: Article

References (24)

1. Kyle RA, Rajkumar SV. Multiple myeloma. N Engl J Med. 2004;351(18):1860-73.
2. Snowden JA, Ahmedzai SH, Ashcroft J, D'Sa S, Littlewood T, Low E, et al. Guidelines for supportive care in multiple myeloma 2011. Br J Haematol. 2011;154 (1):76-103.
3. Offidani M, Corvatta L, Polloni C, Gentili S, Brioni A, Visani G, et al. Infectious complications in patients with multiple myeloma treated with new drug combinations containing thalidomide. Leuk Lymphoma. 2011;52(5):776-85.
4. Nucci M, Anaissie E. Infections in patients with multiple myeloma in the era of highdose therapy and novel agents. Clin Infect Dis. 2009;49(8):1211-25.
5. Landgren O, Kyle RA, Pfeiffer RM, Katzmann JA, Caporaso NE, Hayes RB, et al. Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study. Blood. 2009;113(22):5412-7.
6. Kristinsson SY, Bjorkholm M, Andersson TM, Eloranta S, Dickman PW, Goldin LR, et al. Patterns of survival and causes of death following a diagnosis of monoclonal gammopathy of undetermined significance: a population-based study. Haematologica. 2009;94(12):1714-20.
7. Kristinsson SY, Fears TR, Gridley G, Turesson I, Mellqvist UH, Bjorkholm M, et al. Deep vein thrombosis after monoclonal gammopathy of undetermined significance and multiple myeloma. Blood. 2008;112 (9):3582-6.
8. Bida JP, Kyle RA, Therneau TM, Melton LJ 3rd, Plevak MF, Larson DR, et al. Disease associations with monoclonal gammopa-thy of undetermined significance: a population-based study of 17,398 patients. Mayo Clin Proc. 2009;84(8):685-93.
9. Gregersen H, Madsen KM, Sorensen HT, Schonheyder HC, Ibsen JS, Dahlerup JF. The risk of bacteremia in patients with monoclonal gammopathy of undetermined significance. Eur J Haematol. 1998;61(2): 140-4.
10. Mitrevski M, Granata M, Sedati P, Rota F, De Santis A, Remotti D, et al. Sterile abscesses complicating monoclonal gammopathy of undetermined significance. Eur J Haematol. 2008;81(3):246.
11. Fournie P, Malecaze F, Coullet J, Arne JL. Pyoderma gangrenosum with necrotizing sclerokeratitis after cataract surgery. J Cataract Refract Surg. 2007;33(11):1987-90.
12. Amara S, Dezube BJ, Cooley TP, Pantanowitz L, Aboulafia DM. HIV-associated monoclonal gammopathy: a retrospective analysis of 25 patients. Clin Infect Dis. 2006;43(9):1198-205.
13. Kristinsson SY, Pfeiffer RM, Bjorkholm M, Goldin LR, Schulman S, Blimark C, et al. Arterial and venous thrombosis in monoclonal gammopathy of undetermined significance and multiple myeloma: a populationbased study. Blood. 2010;115(24):4991-8.
14. Broder S, Humphrey R, Durm M, Blackman M, Meade B, Goldman C, et al. Impaired synthesis of polyclonal (non-paraprotein) immunoglobulins by circulating lymphocytes from patients with multiple myeloma Role of suppressor cells. N Engl J Med. 1975;293(18):887-92.
15. Hunter ZR, Manning RJ, Hanzis C, Ciccarelli BT, Ioakimidis L, Patterson CJ, et al. IgA and IgG hypogammaglobulinemia in Waldenstrom's macroglobulinemia. Haematologica. 2010;95(3):470-5.
16. Kyle RA, Therneau TM, Rajkumar SV, Larson DR, Plevak MF, Offord JR, et al. Prevalence of monoclonal gammopathy of undetermined significance. N Engl J Med. 2006;354(13):1362-9.
17. Chanan-Khan A, Sonneveld P, Schuster MW, Stadtmauer EA, Facon T, Harousseau JL, et al. Analysis of herpes zoster events among bortezomib-treated patients in the phase III APEX study. J Clin Oncol. 2008; 26(29):4784-90.
18. Babel N, Schwarzmann F, Pruss A, Volk HD, Reinke P. Monoclonal gammopathy of undetermined significance (MGUS) is associated with an increased frequency of Epstein-Barr Virus (EBV) latently infected B lymphocytes in long-term renal transplant patients. Transplant Proc. 2004;36(9):2679-82.
19. Brown LM, Gridley G, Check D, Landgren O. Risk of multiple myeloma and monoclonal gammopathy of undetermined significance among white and black male United States veterans with prior autoimmune, infectious, inflammatory, and allergic disorders. Blood. 2008;111(7):3388-94.
20. Landgren O, Rapkin JS, Mellemkjaer L, Gridley G, Goldin LR, Engels EA. Respiratory tract infections in the pathway to multiple myeloma: a population-based study in Scandinavia. Haematologica. 2006;91(12):1697-700.
21. Baldini L, Guffanti A, Cesana BM, Colombi M, Chiorboli O, Damilano I, et al. Role of different hematologic variables in defining the risk of malignant transformation in monoclonal gammopathy. Blood. 1996;87 (3):912-8.
22. Landgren O, Kristinsson SY, Goldin LR, Caporaso NE, Blimark C, Mellqvist UH, et al. Risk of plasma cell and lymphoproliferative disorders among 14621 first-degree relatives of 4458 patients with monoclonal gammopathy of undetermined significance in Sweden. Blood. 2009;114(4):791-5.
23. Turesson I, Linet MS, Bjorkholm M, Kristinsson SY, Goldin LR, Caporaso NE, et al. Ascertainment and diagnostic accuracy for hematopoietic lymphoproliferative malignancies in Sweden 1964-2003. Int J Cancer. 2007;121(10):2260-6.
24. Torner A, Dickman P, Duberg AS, Kristinsson S, Landgren O, Bjorkholm M, et al. A method to visualize and adjust for selection bias in prevalent cohort studies. Am J Epidemiol. 2011;174(8):969-76.