Hypoxia-specific GM-CSF-overexpressing neural stem cells improve graft survival and functional recovery in spinal cord injury

Gene Therapy

Volumn 19, Issue 5, 2012, Pages 513-521

  Kim, H J ^a   Oh, J S ^a   An, S S ^a   Pennant, W A ^a   Gwak, S J ^a   Kim, A N ^b   Han, P K ^c   Yoon, D H ^a   Kim, K N ^a   Ha, Y ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Jeju National University School of Medicine   (South Korea)

^c YALE UNIVERSITY   (United States)

Author keywords

GM CSF; neural stem cells; spinal cord injury

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYDROGEN PEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; GENE EXPRESSION; GENE OVEREXPRESSION; GRAFT SURVIVAL; HYPOXIA; IN VITRO STUDY; LOCOMOTION; MALE; MOUSE; NEURAL STEM CELL; NEURAL STEM CELL TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY;

ANIMALS; CELL HYPOXIA; ENHANCER ELEMENTS, GENETIC; ERYTHROPOIETIN; GENE TRANSFER TECHNIQUES; GRAFT SURVIVAL; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; MALE; NEURAL STEM CELLS; PLASMIDS; PROMOTER REGIONS, GENETIC; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SIMIAN VIRUS 40; SPINAL CORD INJURIES;

RATTUS;

EID: 84862141213     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2011.137     Document Type: Article

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