Bovine AAV transcytosis inhibition by tannic acid results in functional expression of CFTR in vitro and altered biodistribution in vivo

Gene Therapy

Volumn 19, Issue 5, 2012, Pages 576-581

  Di Pasquale, G ^a   Ostedgaard, L ^b   Vermeer, D ^b   Swaim, W D ^a   Karp, P ^c   Chiorini, J A ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

BAAV; bovine adeno associated virus; CFTR; tannic acid; transcytosis

Indexed keywords

PARVOVIRUS VECTOR; TANNIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; HEART; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER; LUNG; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; STERNUM; STOMACH; TRANSCYTOSIS; VIRAL GENE THERAPY;

ANIMALS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DEPENDOVIRUS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; MICE; RESPIRATORY MUCOSA; TANNINS; TISSUE DISTRIBUTION; TRANSCYTOSIS;

BOVINAE; BOVINE ADENO-ASSOCIATED VIRUS;

EID: 84862135306     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2011.138     Document Type: Article

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