An LC-MS/MS method for determination of jujuboside A in rat plasma and its application to pharmacokinetic studies

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 899, Issue , 2012, Pages 21-26

  Liu, Changhui ^a   Li, Yingyi ^a   Zhong, Yanhua ^a   Huang, Xiaotao ^a   Zheng, Xia ^a   Li, Neng ^a   He, Shaoling ^a   Mi, Suiqing ^a   Wang, Ningsheng ^a  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Jujuboside A; LC MS MS; Pharmacokinetics; Rat plasma

Indexed keywords

ANALYTES; AUTOSAMPLERS; CORRELATION COEFFICIENT; FREEZE-THAW; ION ELECTROSPRAY IONIZATION; JUJUBOSIDE A; LC-MS/MS; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY COUPLED TO TANDEM MASS SPECTROMETRY; LOWER LIMIT OF QUANTIFICATIONS; MATRIX EFFECTS; MULTIPLE-REACTION MONITORING MODES; PHARMACOKINETIC STUDIES; RAT PLASMA; ROOM TEMPERATURE; SENSITIVE METHOD; SOLID-PHASE EXTRACTION;

ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS;

BODY FLUIDS;

JUJUBOSIDE A; TRITERPENOID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DRUG DETERMINATION; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; FREEZE THAWING; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; ROOM TEMPERATURE; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; FEMALE; HUMANS; MALE; RATS; RATS, SPRAGUE-DAWLEY; SAPONINS; TANDEM MASS SPECTROMETRY; ZIZIPHUS;

RATTUS;

EID: 84862133731     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.04.029     Document Type: Article

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