Viral nervous necrosis virus persistently replicates in the central nervous system of asymptomatic gilthead seabream and promotes a transient inflammatory response followed by the infiltration of IgM+ B lymphocytes

Developmental and Comparative Immunology

Volumn 37, Issue 3-4, 2012, Pages 429-437

  López Muñoz, Azucena ^a,b   Sepulcre, María P ^a,b   García Moreno, Diana ^a,b   Fuentes, Inmaculada ^a,b   Béjar, Julia ^c   Manchado, Manuel ^d   Álvarez, M Carmen ^c   Meseguer, José ^a,b   Mulero, Victoriano ^a,b  

^a UNIVERSITY OF MURCIA   (Spain)

^b Instituto Murciano de Investigacion Biosanitaria IMIB   (Spain)

^c UNIVERSITY OF MÁLAGA   (Spain)

^d IFAPA CENTRO EL TORUÑO   (Spain)

Author keywords

Blood brain barrier; Fish; Viral infection; VNNV

Indexed keywords

CD4 ANTIGEN; CD8ALPHA ANTIGEN; COAT PROTEIN; COLONY STIMULATING FACTOR RECEPTOR; CYTOKINE; IMMUNOGLOBULIN M; INTERFERON; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; T LYMPHOCYTE RECEPTOR BETA CHAIN; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 9; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASYMPTOMATIC INFECTION; B LYMPHOCYTE; BRAIN TISSUE; CC CHEMOKINE LIGAND 4 GENE; CD4 GENE; CD8ALPHA GENE; CENTRAL NERVOUS SYSTEM INFECTION; COAT PROTEIN GENE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE INDUCTION; HEAD KIDNEY; IMMUNE RESPONSE GENE; INNATE IMMUNITY; INTERLEUKIN 1BETA GENE; INTERLEUKIN 8 GENE; LYMPHOCYTIC INFILTRATION; MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR GENE; NONHUMAN; PRIORITY JOURNAL; PTGS2 GENE; SEA BREAM; SPARUS AURATA; T CELL RECEPTOR BETA CHAIN GENE; TOLL LIKE RECEPTOR 22 GENE; TOLL LIKE RECEPTOR 5 GENE; TOLL LIKE RECEPTOR 9 GENE; TRANSFORMING GROWTH FACTOR BETA1 GENE; TUMOR NECROSIS FACTOR ALPHA GENE; TYPE I INTERFERON GENE; VIRAL NERVOUS NECROSIS VIRUS; VIRUS; VIRUS GENE; VIRUS LOAD; VIRUS REPLICATION; VIRUS VIRULENCE;

SPARUS AURATA; STRIPED JACK NERVOUS NECROSIS VIRUS;

EID: 84862132167     PISSN: 0145305X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dci.2012.02.007     Document Type: Article

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