Identification of factors regulating Escherichia coli 2,3-butanediol production by continuous culture and metabolic flux analysis

Journal of Microbiology and Biotechnology

Volumn 22, Issue 5, 2012, Pages 659-667

  Lu, Mingshou ^a   Lee, Soojin ^a   Kim, Borim ^a   Park, Changhun ^a   Oh, Minkyu ^b   Park, Kyungmoon ^c   Lee, Sang Yup ^d   Lee, Jinwon ^a  

^a Sogang University   (South Korea)

^b Korea University   (South Korea)

^c Hong Ik University   (South Korea)

^d Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

2,3 butanediol fermentation; Continuous culture; Intracellular metabolic measurements; Metabolic flux analysis; pH influence

Indexed keywords

2,3 BUTANEDIOL; ACETIC ACID; FORMIC ACID; LACTIC ACID; SUCCINIC ACID;

ACIDITY; ANALYTIC METHOD; ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; BACTERIUM MUTANT; BIOMASS PRODUCTION; BIOSYNTHESIS; CELL GROWTH; CITRIC ACID CYCLE; CONTINUOUS CULTURE; CONTROLLED STUDY; CULTURE OPTIMIZATION; ESCHERICHIA COLI; EXTRACELLULAR METABOLITE CONCENTRATION; FERMENTATION; GLYCOLYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRACELLULAR METABOLITE CONCENTRATION; KLEBSIELLA PNEUMONIAE; MASS SPECTROMETRY; METABOLIC FLUX ANALYSIS; METABOLIC PARAMETERS; METABOLITE; NEUTRAL PH; NONHUMAN; PENTOSE PHOSPHATE CYCLE; PH; QUADRUPOLE TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; WILD TYPE;

BACTERIAL PROTEINS; BIOSYNTHETIC PATHWAYS; BUTYLENE GLYCOLS; CULTURE MEDIA; ESCHERICHIA COLI; FERMENTATION; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC ENGINEERING; KLEBSIELLA PNEUMONIAE;

ESCHERICHIA COLI;

EID: 84862096503     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.1112.12018     Document Type: Article

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