T2-weighted and diffusion-weighted MRI for discriminating benign from malignant focal liver lesions: Diagnostic abilities of single versus combined interpretations

Journal of Magnetic Resonance Imaging

Volumn 35, Issue 6, 2012, Pages 1388-1396

  Haradome, Hiroki ^a,b   Grazioli, Luigi ^a   Morone, Mario ^a   Gambarini, Sebastiana ^a   Kwee, Thomas C ^c   Takahara, Taro ^c   Colagrande, Stefano ^d  

^a UNIVERSITY OF BRESCIA   (Italy)

^b KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d CAREGGI UNIVERSITY HOSPITAL   (Italy)

Author keywords

diffusion weighted imaging; focal liver lesions; T2 weighted imaging

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; BILE DUCT CARCINOMA; CHILD; DIAGNOSTIC ACCURACY; DIFFUSION WEIGHTED IMAGING; FEMALE; FOCAL LIVER LESION; FOLLOW UP; HEPATITIS; HEPATITIS B; HEPATITIS C; HUMAN; IMAGE ANALYSIS; LIVER ABSCESS; LIVER CIRRHOSIS; LIVER METASTASIS; LIVER TUMOR; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RADIODIAGNOSIS; RETROSPECTIVE STUDY; SCHOOL CHILD; T2 WEIGHTED IMAGING; VIRUS HEPATITIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; DIAGNOSIS, DIFFERENTIAL; DIFFUSION MAGNETIC RESONANCE IMAGING; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; OBSERVER VARIATION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 84862095803     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.23573     Document Type: Article

References (36)

1. Namimoto T, Yamashita Y, Sumi S, Tang Y, Takahashi M,. Focal liver masses: characterization with diffusion-weighted echo-planar MR imaging. Radiology 1997; 204: 739-744. (Pubitemid 27369034)
2. Ichikawa T, Haradome H, Hachiya J, Nitatori T, Araki T,. Diffusion weighted MR imaging with a single-shot echoplanar sequence: detection and characterization of focal hepatic lesions. Am J Roentgenol 1998; 170: 397-402. (Pubitemid 28083846)
3. Yamada I, Aung W, Himeno Y, Nakagawa T, Shibuya H,. Diffusion coefficients in abdominal organs and hepatic lesions: evaluation with intravoxel incoherent motion echo-planar MR imaging. Radiology 1999; 210: 617-623. (Pubitemid 29124018)
4. Kim T, Murakami T, Takahashi S, Hori M, Tsuda K, Nakamura H,. Diffusion-weighted single-shot echoplanar MR imaging for liver disease. Am J Roentgenol 1999; 173: 393-398. (Pubitemid 29347365)
5. Taouli B, Vilgrain V, Dumont E, Daire JL, Fan B, Menu Y,. Evaluation of liver diffusion isotropy and characterization of focal hepatic lesions with two single-shot echo-planar MR imaging sequences: prospective study in 66 patients. Radiology 2003; 226: 71-78. (Pubitemid 36163910)
6. Yoshikawa T, Kawamitsu H, Mitchell DG, et al. ADC measurement of abdominal organs and lesions using parallel imaging technique. Am J Roentgenol 2006; 187: 1521-1530. (Pubitemid 44788683)
7. Coenegrachts K, Delanote J, Ter Beek L, et al. Improved focal liver lesion detection: comparison of single-shot diffusion-weighted echoplanar and single-shot T2 weighted turbo spin echo techniques. Br J Radiol 2007; 80: 524-531. (Pubitemid 47343080)
8. Gourtsoyianni S, Papanikolaou N, Yarmenitis S, et al. Respiratory gated diffusion-weighted imaging of the liver: value of apparent diffusion coefficient measurements in the differentiation between most commonly encountered benign and malignant focal liver lesions. Eur Radiol 2008; 18: 486-492.
9. Bruegel M, Gaa J, Waldt S, et al. Diagnosis of hepatic metastasis: comparison of respiration-triggered diffusion-weighted echo-planar MRI and five T2-weighted turbo spin-echo sequences. Am J Roentgenol 2008; 191: 1421-1429.
10. Bruegel M, Holzapfel K, Gaa J, et al. Characterization of focal liver lesions by ADC measurements using a respiratory triggered diffusion diffusion-weighted single-shot echo-planar MR imaging technique. Eur Radiol 2008; 18: 477-485. (Pubitemid 351248179)
11. Parikh T, Drew SJ, Lee VS, et al. Focal liver lesion detection and characterization with diffusion-weighted MR imaging: comparison with standard breath-hold T2-weighted imaging. Radiology 2008; 246: 812-822.
12. Zech CJ, Herrmann KA, Dietrich O, Horger W, Reiser MF, Schoenberg SO,. Black-blood diffusion-weighted EPI acquisition of the liver with parallel imaging: comparison with a standard T2-weighted sequence for detection of focal liver lesions. Invest Radiol 2008; 43: 261-266. (Pubitemid 351416769)
13. Kamel IR, Bluemke DA, Ramsey D, et al. Role of diffusion-weighted imaging in estimating tumor necrosis after chemoembolization of hepatocellular carcinoma. AJR Am J Roentgenol 2003; 181: 708-710. (Pubitemid 37021839)
14. Kamel IR, Bluemke DA, Eng J, et al. The role of functional MR imaging in the assessment of tumor response after chemoembolization in patients with hepatocellular carcinoma. J Vasc Interv Radiol 2006; 17: 505-512. (Pubitemid 44318722)
15. Koh DM, Scurr E, Collins D, et al. Predicting response of colorectal hepatic metastasis: value of pretreatment apparent diffusion coefficients. AJR Am J Roentgenol 2007; 188: 1001-1008. (Pubitemid 46496932)
16. Cui Y, Zhang XP, Sun YS, Tang L, Shen L,. Apparent diffusion coefficient: potential imaging biomarker for prediction and early detection of response to chemotherapy in hepatic metastases. Radiology 2008; 248: 894-900.
17. Taouli B, Tolia AJ, Losada M, et al. Diffusion-weighted MRI for quantification of liver fibrosis: preliminary experience. Am J Roentgenol 2007; 189: 799-806. (Pubitemid 47479760)
18. Taouli B, Chouli M, Martin AJ, Qayyum A, Coakley FV, Vilgrain V,. Chronic hepatitis: role of diffusion-weighted imaging and diffusion tensor imaging for the diagnosis of liver fibrosis and inflammation. J Magn Reson Imaging 2008; 28: 89-95. (Pubitemid 351956470)
19. Yang DM, Jahng GH, Kim HC, et al. The detection and discrimination of malignant and benign focal hepatic lesions: T2 weighted vs. diffusion-weighted MRI. Br J Radiol 2011; 84: 319-326.
20. Bartolozzi C, Cioni D, Donati F, Lencioni R,. Focal liver lesions: MR imaging-pathologic correlation. Eur Radiol 2001; 11: 1374-1388. (Pubitemid 32755622)
21. Horton KM, Bluemke DA, Hruban RH, Soyer P, Fishman EK,. CT and MR imaging of benign hepatic and biliary tumors. Radiographics 1999; 19: 431-451.
22. Zech CJ, Grazioli L, Breuer J, Reiser MF, Schoenberg SO,. Diagnostic performance and description of morphological features of focal nodular hyperplasia in Gd-EOB-DTPA-enhanced liver magnetic resonance imaging: results of a multicenter trial. Invest Radiol 2008; 43: 504-511.
23. Grazioli L, Bondioni MP, Faccioli N, et al. Solid focal liver lesions: dynamic and late enhancement patterns with the dual phase contrast agent gadobenate dimeglumine. Gastrointest Cancer 2010; 41: 221-232.
24. Silva AC, Evans JM, McCullough AE, Jatoi MA, Vargas HE, Hara AK,. MR imaging of hypervascular liver masses: a review of current techniques. Radiographics 2009; 29: 385-402.
25. Rimola J, Forner A, Reig M, et al. Cholangiocarcinoma in cirrhosis: absence of contrast washout in delayed phases by magnetic resonance imaging avoids misdiagnosis of hepatocellular carcinoma. Hepatology 2009; 50: 791-798.
26. Soyer P, Bluemke DA, Reichle R, et al. Imaging of intrahepatic cholangiocarcinoma. 1. Peripheral cholangiocarcinoma. Am J Roentgenol 1995; 165: 1427-1431.
27. Danet IM, Semelka RC, Leonardou P, et al. Spectrum of MRI appearances of untreated metastases. Am J Roentgenol 2003; 181: 809-817. (Pubitemid 37021860)
28. Bruix J, Sherman M,. Practical Guidelines Committee, American Association for the Study of Liver Disease. Management of hepatocellular carcinoma. Hepatology 2005; 42: 1208-1236.
29. Lombardo DM, Baker ME, Spritzer CE, Blinder R, Meyers W, Herfkens RJ,. Hepatic hemangiomas vs metastases: MR differentiation at 1.5 T. AJR Am J Roentgenol 1990; 155: 55-59. (Pubitemid 20218674)
30. Shinmura R, Matsui O, Kobayashi S, et al. Cirrhotic nodules: association between MR imaging signal intensity and intranodular blood supply. Radiology 2005; 237: 512-519. (Pubitemid 41507888)
31. Farraher SW, Jara H, Chang KJ, Ozonoff A, Soto JA,. Differentiation of hepatocellular carcinoma and hepatic metastasis from cysts and hemangiomas with calculated T2 relaxation times and the T1/T2 relaxation times ratio. J Magn Reson Imaging 2006; 24: 1333-1341. (Pubitemid 44871879)
32. Cheng HC, Tsai SH, Chiang JH, Chang CY,. Hyalinized liver hemangioma mimicking malignant tumor at MR imaging (Letter). Am J Roentgenol 1995; 165: 1016-1017.
33. Xu H, Li X, Xie JX, et al. Diffusion-weighted magnetic resonance imaging of focal hepatic nodules in an experimental hepatocellular carcinoma rat model. Acad Radiol 2007; 14: 279-286. (Pubitemid 46329451)
34. Chan JH, Tsui EY, Luk SH,. Diffusion-weighted MR imaging of the liver: distinguishing hepatic abscess from cystic or necrotic tumor. Abdom Imaging 2001; 26: 161-165. (Pubitemid 32187120)
35. Nasu K, Kuroki Y, Tsukamoto T, et al. Diffusion-weighted imaging of surgically resected hepatocellular carcinoma: imaging characteristics and relationship among signal intensity, apparent diffusion coefficient, and histopathologic grade. Am J Roentgenol 2009; 193: 438-444.
36. Muhi A, Ichikawa T, Motosugi U, et al. High-b-value diffusion-weighted MR imaging of hepatocellular lesions: estimation of grade of malignancy of hepatocellular carcinoma. J Magn Reson Imaging 2009; 30: 1005-1011.