More chemicals show epigenetic effects across generations

Environmental Health Perspectives

Volumn 120, Issue 6, 2012, Pages

  Weinhold, Bob ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

2, 3, 7, 8 TETRACHLORODIBENZO PARA DIOXIN; FUEL; PESTICIDE; PLASTIC; UNCLASSIFIED DRUG;

DNA METHYLATION; DNA SEQUENCE; ENVIRONMENTAL EXPOSURE; EPIGENETICS; GENETIC SUSCEPTIBILITY; HUMAN; INFERTILITY; INHERITANCE; NONHUMAN; NOTE; OVARY FOLLICLE; PRIORITY JOURNAL; PUBERTY; SPERM; TESTOSTERONE BLOOD LEVEL;

ANIMALS; ENDPOINT DETERMINATION; EPIGENESIS, GENETIC; FEMALE; HYDROCARBONS; INFERTILITY; MATERNAL EXPOSURE; PESTICIDES; PLASTICS; RATS; TETRACHLORODIBENZODIOXIN;

EID: 84862025678     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.120-a228     Document Type: Note

References (5)

1. Manikkam M, et al. Transgenerational actions of environmenta compounds on reproductive disease and identification of epigenetic biomarkers of ancestral exposures. PLoS ONE 7(2):e31901 (2012); httpg/journal.pone.0031901
2. Focusing on third-generation impacts ensures that any observed effects aren't caused by toxic e the first successive generation or its own next-generation germline
3. Ho DH, Burggren WW. Epigenetics and transgenerational transfer: a physiological perspective. J Exp Biol 213(1):3-16 (2010); http://dx.doiorg/10.1242/jeb.019752.
4. The mixture of pesticides includes permethrin, a pesticide used on humans and in agriculture, and W,W-diethyl-meta-toluamide (DEET), an insect repellent. The mixture of plastics includes bisphenol A and two phthalates, bis(2-ethylhexyl)phthalate and dibutyl phthalate TCDD is formed during numerous incomplete combustion processes JP-8 is used by a number of military services around the globe for many purposes, including powering aircraft and ground vehicles and for dust control on road surfaces.
5. Anogenital distance is the length from the anus to the base of either the penis or vagina. The index is a standardized way of measuring this distance, accounting for variables such as age, weight, and sex