Emerging point of care tests for influenza: Innovation or status quo

Influenza and other Respiratory Viruses

Volumn 6, Issue 4, 2012, Pages 291-298

  Tayo, Adeoluwa ^a   Ellis, Joanna ^b   Linden Phillips, Luan ^a   Simpson, Sue ^a   Ward, Derek J ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

Diagnosis; Emerging health technology; Influenza; Innovation; Point of care testing

Indexed keywords

ARTICLE; BIOTECHNOLOGICAL PRODUCTION; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; DISEASE CLASSIFICATION; INFLUENZA; NOSE SMEAR; ONLINE SYSTEM; POINT OF CARE TESTING; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK BENEFIT ANALYSIS; SAMPLING; SENSITIVITY AND SPECIFICITY; UNITED KINGDOM;

BIOMEDICAL RESEARCH; CLINICAL LABORATORY TECHNIQUES; GREAT BRITAIN; HUMANS; INFLUENZA, HUMAN; ORTHOMYXOVIRIDAE; POINT-OF-CARE SYSTEMS; SENSITIVITY AND SPECIFICITY; TIME FACTORS; VIROLOGY;

EID: 84862000703     PISSN: 17502640     EISSN: 17502659     Source Type: Journal    
DOI: 10.1111/j.1750-2659.2011.00306.x     Document Type: Article

References (27)

1. National Institute for Health and Clinical Excellence. Amantadine, Oseltamivir and Zanamivir for the Treatment of Influenza. Technology appraisal TA 168. London: NICE, 2009.
2. Zambon M, Hays J, Webster A et al. Diagnosis of influenza in the community, relationship of clinical diagnosis to confirmed virological, serologic or molecular detection of influenza. Arch Intern Med 2001; 161:2116-2122.
3. Centers for Disease Control and Prevention. Influenza symptoms and laboratory diagnostic procedures. Available at (Accessed 11 July 2011).
4. World Health Organisation. Recommended laboratory tests to identify avian influenza A virus in specimens from humans. Revised March 2007. Available at (Accessed 11 July 2011).
5. Centers for Disease Control and Prevention. Guidelines for clinicians on the use of rapid influenza diagnostic tests for the 2010-2011 influenza season. Available at (Accessed 11 July 2011).
6. The Royal College of Pathologists. Guidelines on Point-Of-Care Testing 2004. London: The Royal College of Pathologists, 2004.
7. Price CP. Point of care testing. BMJ 2001; 322:1285-1288.
8. Medical Devices Agency. Management and Use of IVD Point of Care Test Devices. Device Bulletin DB(NI)2002/03. Belfast: Department of Health, Social Services and Public Safety, 2002.
9. World Health Organisation (WHO). Sexually transmitted disease diagnostics initiative. Available at (Accessed 10 June 2010).
10. Ward P. Near-patient testing will improve the control of sexually transmitted infections, the arguments in favour. Sex Transm Infect 2006; 82:506-508.
11. Harnden A, Brueggemann A, Shepperd S et al. Near patient testing in children in primary care: comparison with laboratory test. BMJ 2003; 326:480.
12. Hobbs FDR, Delaney BC, Fitzmaurice DA et al. A review of near patient testing in primary care. Health Technol Assess 1997; 1:15-25.
13. Cazacu AC, Greer J, Taherivand M et al. Comparison of lateral-flow immunoassay and enzyme immunoassay with viral culture for rapid detection of influenza virus in nasal wash specimens from children. J Clin Microbiol 2003; 41:2132-2134.
14. Ruest A, Michaud S, Deslandes S et al. Comparison of the Directigen Flu A+B test, the QuickVue Influenza test, and clinical case definition to viral culture and reverse transcription-PCR for rapid diagnosis of influenza virus infection. J Clin Microbiol 2003; 41:3487-3493.
15. Mehta T, McGrath E, Bheemreddy S et al. Detection of oseltamivir resistance during treatment of 2009 H1N1 influenza virus infection in immunocompromised patients: utility of cycle threshold values of qualitative real-time reverse transcriptase PCR. J Clin Microbiol 2010; 48:4326-4328.
16. Uyeki TM, Prasad R, Vukotich C et al. Low sensitivity of rapid diagnostic test for influenza. Clin Infect Dis 2009; 48:e89-e92.
17. Vasoo S, Stevens J, Singh K. Rapid antigen tests for diagnosis of pandemic (swine) influenza A/H1N1. Clin Infect Dis 2009; 49:1090-1093.
18. Agoritsas K, Mack K, Bonsu BK et al. Evaluation of the Quidel QuickVue test for detection of influenza A and B viruses in the pediatric emergency medicine setting by use of three specimen collection methods. J Clin Microbiol 2006; 44:2638-2641.
19. Foo H, Dwyer DE. Rapid tests for the diagnosis of influenza. Australian Prescriber 2009; 32:65-67.
20. Seventh Framework Programme (FP7). Portable automated test for fast detection and surveillance of influenza (PORTFASTFLU). Available at (Accessed 11 July 2011).
21. Seventh Framework Programme (FP7). Development and validation of a microarray based automated diagnostic system for the detection of influenza types and subtypes at point-of-care (FLUARRAY). Available at (Accessed 11 July 2011).
22. World Health Organisation. Pandemic (H1N1) 2009: priority areas for research. Available at (Accessed 11 July 2011).
23. ClinicalTrials.gov. Clinical validation of the point of care MSD influenza test. Available at (Accessed 11 July 2011).
24. Jenny SL, Hu Y, Overduin P et al. Evaluation of the Xpert Flu A Panel nucleic acid amplification-based-point of care test for influenza A virus detection and pandemic H1 subtyping. J Clin Virol 2010; 49:85-89.
25. Yoshimi T, Yoshihiro S, Saori S et al. Development of an immunochromatographic kit for the rapid diagnosis of H5 avian influenza virus infection. Microbiol Immunol 2007; 51:903-907.
26. Fitzmaurice D. Near-patient testing in primary care. Br J Gen Pract 2004; 54:650-651.
27. Smith J, Cook A, Packer C. Point of care tests in sexually transmitted infections- a novel identification method: vertical scanning review; in: Health Technology Assessment International 7th Annual Meeting. Dublin: HTAi, 2010: M4-03.