Improving gene-editing nucleases

Nature Methods

Volumn 9, Issue 6, 2012, Pages 536-

  De Souza, Natalie ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; NUCLEASE; TRANSCRIPTION ACTVATOR LIKE EFFECTOR NUCLEASE; UNCLASSIFIED DRUG; ZINC FINGER NUCLEASE;

DNA END JOINING REPAIR; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME ACTIVITY; GENE MUTATION; GENETIC ENGINEERING; GENOME; METHODOLOGY; PRIORITY JOURNAL; SHORT SURVEY;

EID: 84861994928     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.2060     Document Type: Short Survey

References (4)

1. Ramirez, C.L. et al. Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects. Nucleic Acids Res. published online 28 February 2012.
2. Kim, E. et al. Precision genome engineering with programmable DNA-nicking enzymes. Genome Res. published online 20 April 2012.
3. Wang, J. et al. Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme. Genome Res. published online 10 April 2012.
4. Reyon, D. et al. FLASH assembly of TALENs for high-throughput genome editing. Nat. Biotechnol. 30, 460-465 (2012).