Clinical profile and complications of childhood- and adolescent-onset type 2 diabetes seen at a diabetes center in south India

Diabetes Technology and Therapeutics

Volumn 14, Issue 6, 2012, Pages 497-504

  Amutha, Anandakumar ^a   Datta, Manjula ^a   Unnikrishnan, Ranjit ^a   Anjana, Ranjit Mohan ^a   Mohan, Viswanathan ^a  

^a MADRAS DIABETES RESEARCH FOUNDATION   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; C PEPTIDE; CHOLESTEROL; CREATININE; GLUCOSE; GLUTAMATE DECARBOXYLASE ANTIBODY; GLYCOSYLATED HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AGE; ARTICLE; BIOTHESIOMETRY; BODY HEIGHT; BODY MASS; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CLINICAL ASSESSMENT; CLINICAL FEATURE; CREATININE URINE LEVEL; DIABETIC MICROANGIOPATHY; DIABETIC NEPHROPATHY; DIABETIC NEUROPATHY; DIABETIC RETINOPATHY; DIASTOLIC BLOOD PRESSURE; DISEASE DURATION; EYE PHOTOGRAPHY; FAMILY HISTORY; FEMALE; GLUCOSE BLOOD LEVEL; HEALTH CENTER; HUMAN; IMMUNOASSAY; INDIA; JUVENILE DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; ONSET AGE; PERCEPTIVE THRESHOLD; PREVALENCE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; URBAN AREA; URINARY EXCRETION; VIBRATION SENSE; WAIST CIRCUMFERENCE;

ADOLESCENT; AGE DISTRIBUTION; AGE OF ONSET; ALBUMINURIA; ANALYSIS OF VARIANCE; BLOOD PRESSURE; BODY MASS INDEX; C-PEPTIDE; CHILD; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; DIABETIC NEUROPATHIES; DIABETIC RETINOPATHY; FEMALE; HUMANS; INDIA; MALE; PREVALENCE; RISK ASSESSMENT; RISK FACTORS; SEX DISTRIBUTION; YOUNG ADULT;

EID: 84861975870     PISSN: 15209156     EISSN: 15578593     Source Type: Journal    
DOI: 10.1089/dia.2011.0283     Document Type: Article

References (43)

1. Shaw J: Epidemiology of childhood type 2 diabetes and obesity. Pediatr Diabetes 2007;8(Suppl 9):7-15.
2. American Diabetes Association: Type 2 diabetes in children and adolescents. Diabetes Care 2000;23:381-389.
3. Liu LL, Yi JP, Beyer J, Mayer-Davis EJ, Dolan LM, Dabelea DM, Lawrence JM, Rodriguez BL, Marcovina SM, Waitzfelder BE, Fujimoto WY; SEARCH for Diabetes in Youth Study Group: Type 1 and type 2 diabetes in Asian and Pacific Islander U.S. youth: the SEARCH for Diabetes in Youth Study. Diabetes Care 2009;32(Suppl 2):S133-S140.
4. Scott CR, Smith JM, CradockMM, Pihoker C:Characteristics of youth onset non insulin dependent diabetes mellitus and insulin dependent diabetes mellitus. Pediatrics 1997;100:84-91.
5. Hotu S, Carter B, Watson PD, Cutfield WS, Cundy T: Increasing prevalence of type 2 diabetes in adolescents. J Paediatr Child Health 2004;40:201-204. (Pubitemid 38570272)
6. Ramachandran A, Snehalatha C, Satyavani K, Sivasankari S, Vijay V: Type 2 diabetes in Asian-Indian urban children. Diabetes Care 2003;26:1022-1025. (Pubitemid 36929242)
7. World Health Organization: Physical Status: The Use and Interpretation of Anthropometry: A Report of a WHO Expert Committee. Geneva: World Health Organization, 1995.
8. Snehalatha C, Ramachandran A, Mohan V, Viswanathan M: Pancreatic beta cell response in insulin treated NIDDM patients limitations of a random C-peptide measurement. Diabete Metab 1987;13:27-30. (Pubitemid 17043980)
9. Ramachandran A, Mohan V, Snehalatha C, Bharani G, Chinnikrishnudu M, Mohan R, Viswanathan M: Clinical features of diabetes in the young as seen at a diabetes centre in south India. Diabetes Res Clin Pract 1988;4:117-125. (Pubitemid 18025804)
10. Amutha A, Datta M, Unnikrishnan IR, Anjana RM, Rema M, Venkat Narayan KM, Mohan V: Clinical profile of diabetes in the young seen between 1992 and 2009 at a specialist diabetes centre in south India. Prim Care Diabetes 2011;5:223-229.
11. Alberti KG, Zimmet P: Definition diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus, provisional report of a WHO Consultation. Diabet Med 1998;15:539-553. (Pubitemid 28319935)
12. Fida S, Myers M, Mackay IR, Zimmet PZ, Mohan V, Deepa R, Rowley MJ: Antibodies to diabetes-associated autoantigens in Indian patients with Type 1 diabetes: prevalence of anti-ICA512/IA2 and anti-SOX13. Diabetes Res Clin Pract 2001;52:205-211. (Pubitemid 32385333)
13. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus: Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 1997;20:1183-1197.
14. Mohan V, Nagalotimath SJ, Yajnik CS, Tripathy BB: Fibrocalculous pancreatic diabetes. Diabetes Metab Rev 1998;14:153-170. (Pubitemid 28346262)
15. de Onis M, Onyango AW, Borghi E, Siyam A, Nishida C, Siekmann J: Development of a WHO growth reference for school-aged children and adolescents. Bull World Health Organ 2007;85:660-667. (Pubitemid 47416716)
16. Zimmet P, Alberti KG, Kaufman F, Tajima N, Silink M, Arslanian S, Wong G, Bennett P, Shaw J, Caprio S; IDF Consensus Group: The metabolic syndrome in children and adolescents: an IDF consensus report. Pediatr Diabetes 2007;8:299-306. (Pubitemid 47422902)
17. Early Treatment of Diabetic Retinopathy Study Research Group: Grading diabetic retinopathy from stereoscopic colour fundus photographs: an extension of the modified Airlie House classification: ETDRS report number 10. Ophthalmology 1991;98:786-806.
18. Pradeepa R, Anjana RM, Unnikrishnan R, Ganesan A, Mohan V, Rema M: Risk factors for microvascular complications of diabetes among South Indian subjects with type 2 diabetes - the Chennai Urban Rural Epidemiology Study (CURES) Eye Study-5. Diabetes Technol Ther 2010;12:755-761.
19. Pradeepa R, Rema M, Vignesh JP, Deepa M, Deepa R, Mohan V: Prevalence and risk factors for diabetic neuropathy in an urban South Indian population: the Chennai Urban Rural Epidemiology Study (CURES-55). Diabet Med 2008;25:407-412. (Pubitemid 351490116)
20. McMahon SK, Haynes A, Ratnam N, Grant MT, Carne CL, Jones TW, Davis EA: Increase in type 2 diabetes in children and adolescents in Western Australia. Med J Aust 2004;180:459-461. (Pubitemid 38628444)
21. Likitmaskul S, Kiattisathavee P, Chaichanwatanakul K, Punnakanta L, Angsusingha K, Tuchinda C: Increasing prevalence of type 2 diabetes mellitus in Thai children and adolescents associated with increasing prevalence of obesity. J Pediatr Endocrinol Metab 2003;16:71-77. (Pubitemid 37259095)
22. Anjana RM, Pradeepa R, Deepa M, Datta M, Sudha V, Unnikrishnan R, Bhansali A, Joshi SR, Joshi PP, Yajnik CS, Dhandhania VK, Nath LM, Das AK, Rao PV, Madhu SV, Shukla DK, Kaur T, Priya M, Nirmal E, Parvathi SJ, Subhashini S, Subashini R, Ali MK, Mohan V; ICMR-INDIAB Collaborative Study Group: Prevalence of diabetes and prediabetes (impaired fasting glucose and/or impaired glucose intolerance) in urban and rural India: Phase I results of the Indian Council of Medical Research-INdia DIABetes (ICMR-INDAB) study. Diabetologia 2011;54:3022-3027.
23. Unwin N, Whiting D, Guariguata L, Ghyoot G, Gan D: IDF Diabetes Atlas, 5th ed. Brussels: International Diabetes Federation, 2011.
24. Marwaha RK, Tandon N, Singh Y, Aggarwal R, Grewal K, Mani K: A study of growth parameters and prevalence of overweight and obesity in school children from Delhi. Indian Pediatr 2006;43:943-952. (Pubitemid 46405656)
25. Ramachandran A, Snehalatha C, Vinitha R, Thayyil M, Kumar CK, Sheeba L, Joseph S, Vijay V: Prevalence of overweight in urban Indian adolescent school children. Diabetes Res Clin Pract 2002;57:185-190. (Pubitemid 34765735)
26. Chhatwal J, Verma M, Riar SK: Obesity among pre-adolescent and adolescents of a developing country (India). Asia Pac J Clin Nutr 2004;13:231-235. (Pubitemid 39329877)
27. Shanthi Rani CS, Rema M, Deepa R, Premalatha G, Ravikumar R, Mohan A, Sastry NG, Ramu M, Saroja R, Kayalvizhi G, Mohan V: The Chennai Urban Population Study (CUPS) - methodological details - (CUPS PAPER NO. 1). Int J Diabetes Dev Countries 1999;19:149-155.
28. Deepa M, Pradeepa R, Rema M, Anjana RM, Deepa R, Shanthirani S, Mohan V: The Chennai Urban Rural Epidemiology Study (CURES) - study design and methodology (urban component) (CURES-I). J Assoc Physicians India 2003;51:863-870. (Pubitemid 41279865)
29. Anjana RM, Pradeepa R, Deepa M, Datta M, Sudha V, Unnikrishnan R, Nath LM, Das AK, Madhu SV, Rao PV, Shukla DK, Kaur T, Ali MK, Mohan V: The Indian Council of Medical Research-India Diabetes (ICMR-INDIAB) Study: methodological details. J Diabetes Sci Technol 2011;5:906-914.
30. Unnikrishnan AG, Bhatia E, Bhatia V, Bhadada SK, Sahay RK, Kannan A, Kumaravel V, Sarma D, Ganapathy B, Thomas N, John M, Jayakumar RV, Kumar H, Nair V, Sanjeevi CB: Type 1 diabetes versus type 2 diabetes with onset in persons younger than 20 years of age. Ann NY Acad Sci 2008;1150:239-244.
31. Ehtisham S, Hattersley AT, Dunger DB, Barrett TG: First UK survey of paediatric type 2 diabetes and MODY. Arch Dis Child 2004;89:526-529.
32. Kaufman FR: Insulin resistance syndrome: a pediatric perspective. Endocr Pract 2003;9(Suppl 2):78-80.
33. Deepa M, Farooq S, Deepa R, Manjula D, Mohan V: Prevalence and significance of generalized and central body obesity in an urban Asian Indian population in Chennai, India (CURES: 47). Eur J Clin Nutr 2009;63:259-267.
34. Misra A: We need ethnic-specific criteria for classification of BMI. In: Medeiros-Neto G, Halpern A, Bouchard C, eds. Progress in Obesity Research, Vol. 9. London: John Libbey Eurotext Ltd., 2003:547-553.
35. Das S, Samal KC, Baliarsinha AK, Tripathy BB: Lean (underweight) NIDDM - peculiarities and differences in metabolic and hormonal status - a pilot study. J Assoc Physicians India 1995;43:339-342.
36. Vikram NK, Tandon N,Misra A, SrivastavaMC, Pandey RM, Mithal A, Sharma S, Ajmani A, Madhu SV, Batra CM, Gupta N: Correlates of Type 2 diabetes mellitus in children, adolescents and young adults in north India: a multisite collaborative case-control study. Diabet Med 2006;23:293-298.
37. Ludvigsson J, Carlsson A, Forsander G, Ivarsson S, Kockum I, Lernmark A, Lindblad B, Marcus C, Samuelsson U: C-peptide in the classification of diabetes in children and adolescents. Pediatr Diabetes 2012;13:45-50.
38. Tuomilehto J, Zimmet P, Mackay IR, Koskela P, Vidgren G, Toivanen L, Tuomilehto-Wolf E, Kohtamäki K, Stengård J, Rowley MJ: Antibodies to glutamic acid decarboxylase as predictors of insulin-dependent diabetes mellitus before clinical onset of disease. Lancet 1994;343:1383-1385. (Pubitemid 24167509)
39. Klingensmith GJ, Pyle L, Arslanian S, Copeland KC, Cuttler L, Kaufman F, Laffel L, Marcovina S, Tollefsen SE, Weinstock RS, Linder B; TODAY Study Group: The presence of GAD and IA-2 antibodies in youth with a type 2 diabetes phenotype: results from the TODAY Study. Diabetes Care 2010;33:1970-1975.
40. Reinehr T, Schober E, Wiegand S, Thon A, Holl R; DPV-Wiss Study Group: Beta-cell autoantibodies in children with type 2 diabetes mellitus: subgroup or misclassification? Arch Dis Child 2006;91:473-477. (Pubitemid 43836095)
41. Bonney M, Hing SJ, Fung AT, Stephens MM, Fairchild JM, Donaghue KC, Howard NJ, Silink M: Development and progression of diabetic retinopathy: adolescents at risk. Diabet Med 1995;12:967-973.
42. Yokoyama H, Okudaira M, Otani T, Sato A, Miura J, Takaike H, Yamada H, Muto K, Uchigata Y, Ohashi Y, Iwamoto Y Higher incidence of diabetic nephropathy in type 2 than in type 1 diabetes in early-onset diabetes in Japan. Kidney Int 2005;58:302-311.
43. Eppens MC, Craig ME, Cusumano J, Hing S, Chan AK, Howard NJ, Silink M, Donaghue KC: Prevalence of diabetes complications in adolescents with type 2 compared with type 1 diabetes. Diabetes Care 2006,29:1300-1306. (Pubitemid 44125926)