Xenotransplanted embryonic kidney provides a niche for endogenous mesenchymal stem cell differentiation into erythropoietin-producing tissue

Stem Cells

Volumn 30, Issue 6, 2012, Pages 1228-1235

  Matsumoto, Kei ^a   Yokoo, Takashi ^a,b   Matsunari, Hitomi ^b   Iwai, Satomi ^b,c   Yokote, Shinya ^a   Teratani, Takumi ^d   Gheisari, Yousof ^a   Tsuji, Osahiko ^e   Okano, Hideyuki ^e   Utsunomiya, Yasunori ^a   Hosoya, Tatsuo ^a   Okano, Hirotaka James ^a,e   Nagashima, Hiroshi ^b   Kobayashi, Eiji ^b,d  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b MEIJI UNIVERSITY   (Japan)

^c KITASATO UNIVERSITY   (Japan)

^d JICHI MEDICAL UNIVERSITY   (Japan)

^e KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Anemia; Embryonic programming; Erythropoietin; Mesenchymal stem cells; Transplantation

Indexed keywords

ANGIOPOIETIN RECEPTOR; ENHANCED GREEN FLUORESCENT PROTEIN; ERYTHROPOIETIN; VASCULAR ENDOTHELIAL CADHERIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CAT; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYONAL TISSUE; ENDOTHELIAL PROGENITOR CELL; HUMAN; HUMAN CELL; KIDNEY CELL; MESENCHYMAL STEM CELL; MOUSE; NEPHRON; NONHUMAN; OMENTUM; PROTEIN EXPRESSION; RAT; STEM CELL NICHE; SWINE; TRANSGENIC MOUSE; XENOTRANSPLANTATION;

ANIMALS; CATS; CELL DIFFERENTIATION; CHIMERISM; ERYTHROPOIETIN; HUMANS; KIDNEY; KIDNEY TRANSPLANTATION; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED NOD; MICE, SCID; MICE, TRANSGENIC; RATS; SWINE; TRANSPLANTATION, HETEROLOGOUS;

MUS; MUS MUSCULUS; RATTUS; SUIDAE;

EID: 84861908585     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1101     Document Type: Article

References (32)

1. Kelly C, Flatt CC, McClenaghan NH. Stem-cell based approaches for the treatment of diabetes. Stem Cells Int 2011;2011:424986.
2. Dambrot C, Passier R, Atsma D et al. Cardiomyocyte differentiation of pluripotent stem cells and their use as cardiac disease models. Biochem J 2011;434:25-35.
3. Masuda S, Yokoo T, Sugimito N et al. A simplified in vitro teratoma assay for pluripotent stem cells injected into rodent fetal organ. Cell Med (in press).
4. Naito M. Macrophage heterogeneity in development and differentiation. Arch Histol Cytol 1993;56:331-351. (Pubitemid 24014160)
5. Dekel B, Burakova T, Ben-Hur H et al. Engraftment of human kidney tissue in rat radiation chimera: II Human fetal kidneys display reduced immunogenicity to adoptively transferred human peripheral blood mononuclear cells and exhibit rapid growth and development. Transplantation 1997;64:1550-1558. (Pubitemid 28047382)
6. Dekel B, Marcus H, Herzel BH et al. In vivo modulation of the allogeneic immune response by human fetal kidneys: The role of cytokines, chemokines, and cytolytic effector molecules. Transplantation 2000;69:1470-1478. (Pubitemid 30238743)
7. Dekel B, Burakova F, Arditti D et al. Human and porcine early kidney precursors as a new source for transplantation. Nat Med 2003;9:53-60. (Pubitemid 36098260)
8. Cascalho M, Platte JL. Xenotransplantation and other means of organ replacement. Nat Rev Immunol 2001;1:154-160. (Pubitemid 33741969)
9. Rossert J, Fouqueray B, Boffa JJ. Anemia management and the delay of chronic renal failure progression. J Am Soc Nephrol 2003;14:S173-S177. (Pubitemid 36750514)
10. Erslev AJ, Besarab A. Erythropoietin in the pathogenesis and treatment of the anemia of chronic renal failure. Kidney Int 1997;51:622-630. (Pubitemid 27157944)
11. Akizawa T, Pisone RL, Akiba T et al. Japanese haemodialysis anaemia management practices and outcomes (1999-2006): Results from the DOPPS. Nephrol Dial Transplant 2008;23:3643-3653.
12. Churchill DN, Macarios D, Attard C et al. Costs associated with erythropoiesis-stimulating agent administration to hemodialysis patients. Nephron Clin Pract 2007;106:c193-c198. (Pubitemid 47172280)
13. Horie M, Sekiya I, Muneta T et al. Intra-articular injected synovial stem cells differentiate into meniscal cells directly and promote meniscal regeneration without mobilization to distant organs in rat massive meniscal defect. Stem Cells 2009;27:878-887.
14. Yokoo T, Fukui A, Matsumoto K et al. Generation of transplantable erythropoietin-producer derived from human mesenchymal stem cells. Transplantation 2008;85:1654-1658.
15. Inoue H, Ohsawa I, Murakami T et al. Development of new inbred transgenic strain of rats with LacZ or GFP. Biochem Biophys Res Commun 2005;329:288-295. (Pubitemid 40255452)
16. Hakamata Y, Murakami T, Kobayashi E. "Firefly rats" as an organ/cellular source for long-term in vivo bioluminescent imaging. Transplantation 2006;81:1179-1184.
17. Kanazawa H, Fujimoto Y, Teratani T et al. Bone marrow-derived mesenchymal stem cells ameliorate hepatic ischemia reperfusion injury in a rat model. PLoS One 2011;6:e19195.
18. Tepper OM, Capla JM, Galiano RD et al. Adult vasculogenesis occurs through in situ recruitment, proliferation, and tubulization of circulating bone marrow-derived cells. Blood 2005;105:1068-1077. (Pubitemid 40170877)
19. Ghisari Y, Yokoo T, Matsumoto K et al. A thermoreversible polymer mediates controlled release of glial cell line-derived neurotrophic factor to enhance kidney regeneration. Artif Organs 2010;34:642-647.
20. Yokoo T, Ohashi T, Utsunomiya Y et al. Genetically modified bone marrow continuously supplies anti-inflammatory cells and suppresses renal injury in mouse Goodpasture syndrome. Blood 2001;98:57-64.
21. Yokoo T, Fukui A, Ohashi T et al. Xenobiotic kidney organogenesis from human mesenchymal stem cells using a growing rodent embryo. J Am Soc Nephrol 2006;17:1026-1034.
22. Yokoo T, Ohashi T, Shen JS et al. Human mesenchymal stem cells in rodent whole embryo culture are reprogrammed to contribute to kidney tissues. Proc Natl Acad Sci USA 2005;102:3296-3300. (Pubitemid 40328039)
23. Matsunari H, Onodera M, Tada N et al. Transgenic-cloned pigs systemically expressing red fluorescent protein, Kusabira-Orange. Cloning Stem Cells 2008;10:313-323.
24. Banas A, Teratani T, Yamamoto Y et al. Adipose tissue-derived mesenchymal stem cells as a source of human hepatocytes. Hepatology 2007;46:219-228. (Pubitemid 47171939)
25. Kagawa N, Silber S, Kuwayama M. Successful vitrification of bovine and human ovarian tissue. Reprod Biomed Online 2009;18:568-577.
26. Ott HC, Mattheisen S, Goh S-K et al. Perfusion-decellularized matrix: Using nature's platform to engineer a bioartificial heart. Nat Med 2008;14:213-221. (Pubitemid 351214548)
27. Uygun BE, Soto-Gutierrez A, Yagi H et al. Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix. Nat Med 2010;16:814-820.
28. Ott HC, Clippinger B, Conrad C et al. Regeneration and orthotopic transplantation of a bioartificial lung. Nat Med 2010;16:927-933.
29. Ross EA, Williams MJ, Hamazaki T et al. Embryonic stem cells proliferate when seeded into kidney scaffolds. J Am Soc Nephrol 2009; 11:2338-2347.
30. Nagashima H, Hiruma K, Saito H et al. Production of live piglets following cryopreservation of embryos derived from in vitro-matured oocytes. Biol Reprod 2007;76:900-905. (Pubitemid 46651231)
31. Elliot J, Rawlings JM, Markwell PJ et al. Survival of cats with naturally occurring chronic renal failure: Effect of dietary management. J Small Anim Pract 2000;41:235-242.
32. Randolph JE, Scarlett JE, Stokol T et al. Expression, bioactivity, and clinical assessment of recombinant feline erythropoietin. Am J Vet Res 2004;65:1355-1366. (Pubitemid 39369277)